Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gary Latham"'
Autor:
Cody Edwards, Bradley Martin, Monica Roberts, Jon Kemppainen, Ryan Routsong, Bryan Killinger, Adrian Lara, Christopher Fraher, Gary Latham, Bradley Hall
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100502- (2023)
Externí odkaz:
https://doaj.org/article/f070d80821e24696848197dcf678c718
Autor:
Bradley Hall, Bryan Killinger, Christopher Fraher, Bradley Martin, Monica Roberts, Jonathan Turner, Pranesh Rao, Ryan Routsong, Gary Latham
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100524- (2023)
Externí odkaz:
https://doaj.org/article/445f1d772f554aa29aa9f672d64499e6
Autor:
Daria A Gaykalova, Elizabeth Mambo, Ashish Choudhary, Jeffery Houghton, Kalyan Buddavarapu, Tiffany Sanford, Will Darden, Alex Adai, Andrew Hadd, Gary Latham, Ludmila V Danilova, Justin Bishop, Ryan J Li, William H Westra, Patrick Hennessey, Wayne M Koch, Michael F Ochs, Joseph A Califano, Wenyue Sun
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233409 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0093102.].
Externí odkaz:
https://doaj.org/article/8c1619d622f047fbb4102119ccdb2917
Autor:
Daria A Gaykalova, Elizabeth Mambo, Ashish Choudhary, Jeffery Houghton, Kalyan Buddavarapu, Tiffany Sanford, Will Darden, Alex Adai, Andrew Hadd, Gary Latham, Ludmila V Danilova, Justin Bishop, Ryan J Li, William H Westra, Patrick Hennessey, Wayne M Koch, Michael F Ochs, Joseph A Califano, Wenyue Sun
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93102 (2014)
Development of head and neck squamous cell carcinoma (HNSCC) is characterized by accumulation of mutations in several oncogenes and tumor suppressor genes. We have formerly described the mutation pattern of HNSCC and described NOTCH signaling pathway
Externí odkaz:
https://doaj.org/article/cf3daae0fc2b4649896c9a86188a7384
Autor:
Joseph A. Califano, Christine H. Chung, Patrick Hennessey, William H. Westra, Rajni Sharma, Justin Bishop, Gary Latham, Alex Adai, Will Darden, Ashish Choudhary, Tiffany Sanford, Kalyan Buddavarapu, Jeffery Houghton, David Sidransky, Elana Fertig, Sun Ahn, Ryan Li, Jason Howard, Nishant Agrawal, Myriam Loyo, Yan Liu, Demetri Arnaoutakis, Elizabeth Mambo, Michael F. Ochs, Daria A. Gaykalova, Wenyue Sun
PDF file - 116K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5e941a7021c8af7371b59f6109de01
https://doi.org/10.1158/0008-5472.22401650.v1
https://doi.org/10.1158/0008-5472.22401650.v1
Autor:
Joseph A. Califano, Christine H. Chung, Patrick Hennessey, William H. Westra, Rajni Sharma, Justin Bishop, Gary Latham, Alex Adai, Will Darden, Ashish Choudhary, Tiffany Sanford, Kalyan Buddavarapu, Jeffery Houghton, David Sidransky, Elana Fertig, Sun Ahn, Ryan Li, Jason Howard, Nishant Agrawal, Myriam Loyo, Yan Liu, Demetri Arnaoutakis, Elizabeth Mambo, Michael F. Ochs, Daria A. Gaykalova, Wenyue Sun
NOTCH1 mutations have been reported to occur in 10% to 15% of head and neck squamous cell carcinomas (HNSCC). To determine the significance of these mutations, we embarked upon a comprehensive study of NOTCH signaling in a cohort of 44 HNSCC tumors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6d2f8c055d1267f1798b66f3e18ffe7
https://doi.org/10.1158/0008-5472.c.6505904
https://doi.org/10.1158/0008-5472.c.6505904
Autor:
Joseph A. Califano, Christine H. Chung, Patrick Hennessey, William H. Westra, Rajni Sharma, Justin Bishop, Gary Latham, Alex Adai, Will Darden, Ashish Choudhary, Tiffany Sanford, Kalyan Buddavarapu, Jeffery Houghton, David Sidransky, Elana Fertig, Sun Ahn, Ryan Li, Jason Howard, Nishant Agrawal, Myriam Loyo, Yan Liu, Demetri Arnaoutakis, Elizabeth Mambo, Michael F. Ochs, Daria A. Gaykalova, Wenyue Sun
PDF file - 82K, Growth effects of NOTCH1 siRNA inhibition in HNSCC cells with wildtype NOTCH1 status. NOTCH1 was downregulated in UPCI-SCC090 (090, top, NOTCH1 wt) and SCC61 (bottom, NOTCH1 wt) by siRNA as described in methods. The effect of NOTCH1 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75d4ae589197fb53125f022a6ca4479
https://doi.org/10.1158/0008-5472.22401659
https://doi.org/10.1158/0008-5472.22401659
Autor:
Joseph A. Califano, Christine H. Chung, Patrick Hennessey, William H. Westra, Rajni Sharma, Justin Bishop, Gary Latham, Alex Adai, Will Darden, Ashish Choudhary, Tiffany Sanford, Kalyan Buddavarapu, Jeffery Houghton, David Sidransky, Elana Fertig, Sun Ahn, Ryan Li, Jason Howard, Nishant Agrawal, Myriam Loyo, Yan Liu, Demetri Arnaoutakis, Elizabeth Mambo, Michael F. Ochs, Daria A. Gaykalova, Wenyue Sun
PDF file - 73K, Significant overexpression of JAG1 (A) and PSEN1 (B) in the tumors with increased copy number gains in comparison to that in the normal tissues in the cohort of 44 HNSCC tumors and 25 normal mucosa. N, normal mucosa; T, HNSCC tumors;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08e115ff5e58882b5545c439747dfc6
https://doi.org/10.1158/0008-5472.22401671.v1
https://doi.org/10.1158/0008-5472.22401671.v1
Autor:
Joseph A. Califano, Christine H. Chung, Patrick Hennessey, William H. Westra, Rajni Sharma, Justin Bishop, Gary Latham, Alex Adai, Will Darden, Ashish Choudhary, Tiffany Sanford, Kalyan Buddavarapu, Jeffery Houghton, David Sidransky, Elana Fertig, Sun Ahn, Ryan Li, Jason Howard, Nishant Agrawal, Myriam Loyo, Yan Liu, Demetri Arnaoutakis, Elizabeth Mambo, Michael F. Ochs, Daria A. Gaykalova, Wenyue Sun
PDF file - 169K, NOTCH pathway activation in HNSCC. A, Immunohistochemical analysis of NOTCH1, HES1 and HEY1 protein expression in HNSCC. Tissue microarray arrays with quadruplicates of samples from each of 56 HNSCC tumor and 11 non-tumor patients we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cd3efd46979b062b1579c40dd36b6b
https://doi.org/10.1158/0008-5472.22401665.v1
https://doi.org/10.1158/0008-5472.22401665.v1
Autor:
Joseph A. Califano, Christine H. Chung, Patrick Hennessey, William H. Westra, Rajni Sharma, Justin Bishop, Gary Latham, Alex Adai, Will Darden, Ashish Choudhary, Tiffany Sanford, Kalyan Buddavarapu, Jeffery Houghton, David Sidransky, Elana Fertig, Sun Ahn, Ryan Li, Jason Howard, Nishant Agrawal, Myriam Loyo, Yan Liu, Demetri Arnaoutakis, Elizabeth Mambo, Michael F. Ochs, Daria A. Gaykalova, Wenyue Sun
PDF file - 111K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1396cb0f9882e511bd50bfe64c0e72c6
https://doi.org/10.1158/0008-5472.22401647.v1
https://doi.org/10.1158/0008-5472.22401647.v1