Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gary K. Yiu"'
Publikováno v:
Biochemical Journal
Invasive migration of carcinoma cells is a prerequisite for the metastatic dissemination of solid tumours. Numerous mechanisms control the ability of cancer cells to acquire a motile and invasive phenotype, and subsequently degrade and invade the bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c569882af95bb8340ef15efb165d57ed
http://europepmc.org/articles/PMC3204871
http://europepmc.org/articles/PMC3204871
Autor:
Alex Toker, Gary K. Yiu
Publikováno v:
Journal of Biological Chemistry. 281:12210-12217
The NFAT (nuclear factor of activated T cells) family of transcription factors plays a fundamental role in the transcriptional regulation of the immune response. However, NFATs are ubiquitously expressed, and recent evidence points to their important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388c63d73b251ec9e9eb62bcf992b4fd
https://doi.org/10.1074/jbc.m600184200
https://doi.org/10.1074/jbc.m600184200
Autor:
Kuan-Chun Huang, Shu-Wing Ng, Gary K. Yiu, Alain G. Jacquemin-Sablon, Deepa Saxena, Roberto Mantovani, Xiaoyan Ni
Publikováno v:
Gene. 342:145-155
Reduced expression of topoisomerase II is one of the mechanisms observed in cell lines and clinical samples that are resistant to topoisomerase II-targeting agents. The Chinese hamster lung cell line DC-3F/9-OH-E made resistant to 9-OH ellipticine an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d3f864255eb54972b1ce96096ff2f9
https://doi.org/10.1016/j.gene.2004.07.033
https://doi.org/10.1016/j.gene.2004.07.033
Prostasin, a Potential Serum Marker for Ovarian Cancer: Identification Through Microarray Technology
Autor:
Steven J. Skates, Gary K. Yiu, Ross S. Berkowitz, Julie Chao, Samuel C. Mok, Michael G. Muto, Kwong Kwok Wong, Daniel W. Cramer
Publikováno v:
JNCI Journal of the National Cancer Institute. 93:1458-1464
BACKGROUND Screening biomarkers for ovarian cancer are needed because of its late stage at diagnosis and poor survival. We used microarray technology to identify overexpressed genes for secretory proteins as potential serum biomarkers and selected pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a3e4c43089568d5f3f9c311099a4f3
https://doi.org/10.1093/jnci/93.19.1458
https://doi.org/10.1093/jnci/93.19.1458
Autor:
Norman B. Hecht, Gary K. Yiu
Publikováno v:
Journal of Biological Chemistry. 272:26926-26933
The mouse protamines are expressed exclusively in postmeiotic male germ cells and are crucial for the compaction of chromatin during the late stages of spermatogenesis. The temporal expression of the two mouse protamines is transcriptionally regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74296346ce50f8db78ce582804fe7943
https://doi.org/10.1074/jbc.272.43.26926
https://doi.org/10.1074/jbc.272.43.26926
Publikováno v:
Biology of Reproduction. 56:1439-1449
Transcriptional regulation of the mouse testis-specific cytochrome c (cyt. C T ) gene was studied by examining DNA-protein interactions in its proximal promoter. Testicular and liver nuclear proteins bound to the cyt. c T gene at sites -105 to -81, +
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ace0e5523d30af955f9b3dd2a54abb
https://doi.org/10.1095/biolreprod56.6.1439
https://doi.org/10.1095/biolreprod56.6.1439
Autor:
Kwok Wai Lo, Shiu-Ying Tsao, Gary K. Yiu, Peter H.K. Choi, Dolly P. Huang, Angela Y.T. Ng, Joseph C.K. Lee
Publikováno v:
Cancer Genetics and Cytogenetics. 54:91-99
A consistent loss of constitutional heterozygosity within a specific chromosome locus in a tumor type is suggestive of a tumor suppressor gene important in the genesis of that tumor. We studied whether such genetic alterations are involved, in the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9a602acdf84ebd9b979e4609477bc7
https://doi.org/10.1016/0165-4608(91)90035-s
https://doi.org/10.1016/0165-4608(91)90035-s
Autor:
Alex Toker, Gary K. Yiu, Sébastien Jauliac, Isaac Rabinovitz, Merav Yoeli-Lerner, Peter Erhardt
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2005, 20, pp.539-50. ⟨10.1016/j.molcel.2005.10.033⟩
Molecular Cell, Cell Press, 2005, 20, pp.539-50. ⟨10.1016/j.molcel.2005.10.033⟩
Molecular Cell, Elsevier, 2005, 20, pp.539-50. ⟨10.1016/j.molcel.2005.10.033⟩
Molecular Cell, Cell Press, 2005, 20, pp.539-50. ⟨10.1016/j.molcel.2005.10.033⟩
International audience; The phosphoinositide 3-kinase (PI 3-K) signaling axis is intimately associated with deregulated cancer cell growth, primarily by promoting increased survival through Akt/PKB (protein kinase B). However, there is relatively lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4806523605423f7072ed1b89e0d1ed9f
https://www.hal.inserm.fr/inserm-00000020/file/article.pdf.pdf
https://www.hal.inserm.fr/inserm-00000020/file/article.pdf.pdf
Autor:
Kwok-Kuen Cheung, Samuel C. Mok, Wood Yee Chan, Gary K. Yiu, Shu Wing Ng, Ross S. Berkowitz, Pui Suen Chan
Secreted protein acidic and rich in cysteine (SPARC) is an extracellular Ca 2+ -binding matricellular glycoprotein that associates with cell populations undergoing migration, morphogenesis, and differentiation. Studies on endothelial cells have estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3904cd297ffbd0d38f1f971a0d578db
https://europepmc.org/articles/PMC1850537/
https://europepmc.org/articles/PMC1850537/
Autor:
Gary K. Yiu, Shu Wing Ng, Sunny H. Jun, Madhuri Palnati, Ross S. Berkowitz, Lee Wen Huang, Yan Liu, Samuel C. Mok
Publikováno v:
Oncogene. 19(15)
p73 is a novel gene that has high sequence homology and similar gene structure to the tumor suppressor gene p53. We analysed p73 in seven ovarian carcinoma cell lines and a total of 63 human borderline and invasive ovarian tumor samples. Loss of hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc15a421f74e6524a551b51f19b36b08
https://pubmed.ncbi.nlm.nih.gov/10773878
https://pubmed.ncbi.nlm.nih.gov/10773878