Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gary K. Iwamoto"'
Publikováno v:
Health Informatics Journal. 24:394-409
Chronic obstructive pulmonary disease is a heterogeneous disease. In this retrospective study, we hypothesize that it is possible to identify clinically relevant phenotypes by applying clustering methods to electronic medical records. We included all
Publikováno v:
Journal of Investigative Medicine. 54:484-489
Background Nitric oxide (NO) is present in the gas phase of the normal human stomach at a high concentration (1-10 ppm). The majority of this NO is produced from the reduction of dietary nitrate to nitrite and finally NO. Generation of this nonenzyma
Publikováno v:
Journal of Asthma. 41:471-476
The fraction of exhaled nitric oxide (FeNO) is elevated in asthmatics compared to normal subjects. Many studies have demonstrated that FeNO correlates with other markers of airway inflammation. The purpose of this study was to assess the clinical uti
Publikováno v:
Annals of Allergy, Asthma & Immunology. 91:567-574
Monocytic cells and alveolar macrophages (AMs) are activated in patients with asthma, producing inflammatory cytokines. This occurs despite a TH2 environment that consists of the cytokines interleukin (IL) 4, IL-10, and IL-13. The mechanism by which
Autor:
Robert L. Williams, Alex H. Krist, Steven H. Woolf, Jon Deshazo, Rebecca S. Etz, Christine C. Nelson, Miria Kano, Crystal Romney, Daniel R. Longo, Paulette Lail Kashiri, Susan Wolver, Jennifer E. DeVoe, Karen L. Stein, Jill Arkind, Jon Puro, Gary K. Iwamoto, Rebecca A. Aycock, Roy T. Sabo
Publikováno v:
Implementation Science : IS
Background Evidence-based preventive services for early detection of cancer and other health conditions offer profound health benefits, yet Americans receive only half of indicated services. Policy initiatives promote the adoption of information tech
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 277:L1051-L1056
The immediate-early (IE) genes of human cytomegalovirus (CMV) can be expressed in monocytic cells and are known to regulate viral and cellular genes. Reactivation of human immunodeficiency virus (HIV-1) may be stimulated by a variety of factors inclu
Autor:
Gary K. Iwamoto, Viswanathan Natarajan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1213:14-20
Lipopolysaccharide (LPS)-induced phospholipase D (PLD) activation was investigated in undifferentiated monocytic leukemic cell lines THP-1 and U-937. Treatment of THP-1 or U-937 cells labelled with [32P]orthophosphate, [32P]acyl GPC or [3H]alkyl GPC
Publikováno v:
The Journal of asthma : official journal of the Association for the Care of Asthma. 42(8)
To assess whether bronchial wall thickening during asthma exacerbations is due to active inflammation in severe asthmatics, we measured bronchial wall thickness and exhaled nitric oxide (FeNO) following treatment. Nine asthmatics were compared with s
Autor:
Gary K. Iwamoto, Neil Hoa, Vimesh Akotia, Hamid M. Said, Ali Pedram, Thomas Y. Ma, Michel Boivin
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 286(3)
Crohn's disease (CD) patients have an abnormal increase in intestinal epithelial permeability. The defect in intestinal tight junction (TJ) barrier has been proposed as an important etiologic factor of CD. TNF-alpha increases intestinal TJ permeabili
Autor:
Richard A. Sidner, Carol T. Schnizlein-Bick, Blake A. Spain, Diaa M. Soliman, David S. Wilkes, Kenneth S. Knox, Gary K. Iwamoto, Homer L. Twigg
Publikováno v:
The American journal of physiology. 276(2)
A CD8+lymphocytic alveolitis occurs in up to 60% of asymptomatic human immunodeficiency virus (HIV)-infected individuals. Early in HIV infection, lymphocytes consist predominantly of cytotoxic T lymphocytes directed against HIV-infected targets. As H