Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Gary J. Quigley"'
Publikováno v:
Journal of Molecular Biology. 236:1154-1168
The water structure in three crystal forms of the left-handed Z-DNA hexamer [d(CGCGCG)]2 has been analyzed. Several common motifs have been found in the first hydration shells. On the convex surface, the major groove of the left-handed conformation,
Publikováno v:
ChemInform. 22
Vinylcyclohexenes substituted allylically on the cyclohexene ring were examined as substrates in the Diels-Alder cycloaddition. In the octalin cycloaddition products, the relative stereochemistry of the one angular hydrogen relative to that of the al
Autor:
Shun-Le Chen, Qi Gao, Dov Rabinovich, Gary J. Quigley, Loren Dean Williams, Martin Egli, Alexander Rich
Publikováno v:
Proceedings of the National Academy of Sciences. 88:2422-2426
Ditercalinium is a synthetic anticancer drug that binds to DNA by bis-intercalation and activates DNA repair processes. In prokaryotes, noncovalent DNA-ditercalinium complexes are incorrectly recognized by the uvrABC repair system as covalent lesions
Autor:
Gary J. Quigley
Publikováno v:
Journal of Crystal Growth. 110:131-136
Effect of allylic substituents on the face selectivity of Diels-Alder reactions of semicyclic dienes
Publikováno v:
Journal of the American Chemical Society. 112:8472-8478
Vinylcyclohexenes substituted allylically on the cyclohexene ring were examined as substrates in the Diels-Alder cycloaddition. In the octalin cycloaddition products, the relative stereochemistry of the one angular hydrogen relative to that of the al
Publikováno v:
Biochemistry. 31(29)
Receptor binding and biological activity properties of human interleukin-1 beta can be dissociated by mutating a single amino acid, arginine 127, to glycine (IL-1 beta R----G) [Gehrke et al. (1990) J. Biol. Chem. 265, 5922-5925]. The mechanism underl
Publikováno v:
Biochemistry. 30(21)
The boundary between two segments of Z-DNA that differ in the phase of their syn-anti alternation about the glycosidic bond is termed a Z-Z junction. Using chemical probes and two-dimensional gel electrophoresis, we examined a Z-Z junction consisting