Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Gary J. Gorbsky"'
Autor:
Gary J. Gorbsky, John R. Daum, Hem Sapkota, Katja Summala, Hitoshi Yoshida, Constantin Georgescu, Jonathan D. Wren, Leonid Peshkin, Marko E. Horb
Publikováno v:
Open Biology, Vol 12, Iss 7 (2022)
The diploid anuran Xenopus tropicalis has emerged as a key research model in cell and developmental biology. To enhance the usefulness of this species, we developed methods for generating immortal cell lines from Nigerian strain (NXR_1018, RRID:SCR_0
Externí odkaz:
https://doaj.org/article/031989c2976844f2b89e26e5884e8494
Publikováno v:
Stem Cell Research, Vol 26, Iss , Pp 1-7 (2018)
The cancer stem cell model postulates that tumors are hierarchically organized with a minor population, the cancer stem cells, exhibiting unlimited proliferative potential. These cells give rise to the bulk of tumor cells, which retain a limited abil
Externí odkaz:
https://doaj.org/article/3fc826f0843d4f089a1be0a11ae39995
Autor:
Sushama Sivakumar, Gary J. Gorbsky
Publikováno v:
Biology Open, Vol 6, Iss 11, Pp 1672-1679 (2017)
Kinetochores move chromosomes on dynamic spindle microtubules and regulate signaling of the spindle checkpoint. The spindle- and kinetochore-associated (Ska) complex, a hexamer composed of two copies of Ska1, Ska2 and Ska3, has been implicated in bot
Externí odkaz:
https://doaj.org/article/9cd790ac385b40469d3c7885c50f558e
Autor:
Tamara Potapova, Gary J. Gorbsky
Publikováno v:
Biology, Vol 6, Iss 1, p 12 (2017)
Mistakes during cell division frequently generate changes in chromosome content, producing aneuploid or polyploid progeny cells. Polyploid cells may then undergo abnormal division to generate aneuploid cells. Chromosome segregation errors may also in
Externí odkaz:
https://doaj.org/article/2aa6d4740ed24f4c8239c1e407c3ad36
Supplementary Legends 1-4 from A High Throughput, Whole Cell Screen for Small Molecule Inhibitors of the Mitotic Spindle Checkpoint Identifies OM137, a Novel Aurora Kinase Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1e83a5389f1ecb666dbb84d5845cce
https://doi.org/10.1158/0008-5472.22381103
https://doi.org/10.1158/0008-5472.22381103
Supplementary Video 1 from A High Throughput, Whole Cell Screen for Small Molecule Inhibitors of the Mitotic Spindle Checkpoint Identifies OM137, a Novel Aurora Kinase Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c11953734648e0955c6aed4d8314d3
https://doi.org/10.1158/0008-5472.22381100.v1
https://doi.org/10.1158/0008-5472.22381100.v1
In mitosis, the kinetochores of chromosomes that lack full microtubule attachments and/or mechanical tension activate a signaling pathway called the mitotic spindle checkpoint that blocks progression into anaphase and prevents premature segregation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4195440a654767bed5b5579bde17ee
https://doi.org/10.1158/0008-5472.c.6499757.v1
https://doi.org/10.1158/0008-5472.c.6499757.v1
Supplementary Video 4 from A High Throughput, Whole Cell Screen for Small Molecule Inhibitors of the Mitotic Spindle Checkpoint Identifies OM137, a Novel Aurora Kinase Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b90cebc0b3eb8a606feb9d3e94a8c93
https://doi.org/10.1158/0008-5472.22381091.v1
https://doi.org/10.1158/0008-5472.22381091.v1
Supplementary Video 3 from A High Throughput, Whole Cell Screen for Small Molecule Inhibitors of the Mitotic Spindle Checkpoint Identifies OM137, a Novel Aurora Kinase Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1357d7dacad1d12de80c0284ce5a93ba
https://doi.org/10.1158/0008-5472.22381094.v1
https://doi.org/10.1158/0008-5472.22381094.v1
Supplementary Video 2 from A High Throughput, Whole Cell Screen for Small Molecule Inhibitors of the Mitotic Spindle Checkpoint Identifies OM137, a Novel Aurora Kinase Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3dfcf4f6d021430516fe0a3b5ce4cb
https://doi.org/10.1158/0008-5472.22381097
https://doi.org/10.1158/0008-5472.22381097