Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gary J. Dozeman"'
Autor:
Margaret E. Kelly, Philip J. Fiore, Gary J. Dozeman, Randall L. De Jong, Ronald E. Seamans, Punam Giri, James G. Davidson, and Timothy P. Puls
Publikováno v:
Organic Process Research & Development. 5:216-225
Efficient, large-scale processes were developed for the preparation of the potent PNP inhibitors 2,6-diamino-3,5-dihydro-7-(3-thienylmethyl)-4H-pyrrolo[3,2-d]pyrimidin-4-one hydrochloride, monohydrate (1) and 2-amino-3,5-dihydro-7-(3-thienylmeth-yl)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5888302fd97ac7d5a4c3de5ca7ddf5c
https://doi.org/10.1021/op000298d
https://doi.org/10.1021/op000298d
Autor:
Edward Mark Davis, and Daniel T. Belmont, Edward A. Lenoir, Ellis James E, Phillip L. Brower, Gary J. Dozeman
Publikováno v:
Organic Process Research & Development. 5:226-233
The process development of a route for preparing CI-1020 on pilot-plant scale is described in 55% overall yield. Hydrocyanation conditions are described which use acetone cyanohydrin catalyzed by tetramethylammonium hydroxide and which provide the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77706849b3e46f018b47082e723885aa
https://doi.org/10.1021/op010200a
https://doi.org/10.1021/op010200a
Publikováno v:
Organic Process Research & Development. 1:137-148
A manufacturing process to prepare the ACAT inhibitor 2,6-diisopropylphenyl [(2,4,6-triisopropylphenyl)acetyl]sulfamate (1; CI-1011) has been developed and successfully demonstrated on a pilot scale. Commercially available 1,3,5-triisopropylbenzene (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1524bd5da404387d73a705fdcbe13ee1
https://doi.org/10.1021/op9600419
https://doi.org/10.1021/op9600419
Autor:
Philip J. Fiore, Timothy P. Puls, Ronald E. Seamans, Randall L. De Jong, Margaret E. Kelly, James G. Davidson, Punam Giri, Gary J. Dozeman
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b963162c868cf79220bbd4e67c69246
https://doi.org/10.1002/chin.200143171
https://doi.org/10.1002/chin.200143171
Autor:
Ellis James E, Edward A. Lenoir, Edward Mark Davis, Daniel Belmont, Gary J. Dozeman, Phillip L. Brower
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a192cd8b6c25ffa1cfdeee325d4e754
https://doi.org/10.1002/chin.200142147
https://doi.org/10.1002/chin.200142147