Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gary J. Brouhard"'
Autor:
Gary J. Brouhard, Scott Forth, Tatyana Bodrug, Larisa Gheber, Jawdat Al-Bassam, Jennifer Major, Steven S. Rosenfeld, Malina K. Iwanski, Himanshu Pandey, Adam G. Hendricks, Stanley Nithiananatham, Ignas Gaska, Sayaka Inagaki
The conserved kinesin-5 bipolar tetrameric motors slide apart microtubules during mitotic spindle assembly and elongation. Kinesin-5 bipolar organization originates from its conserved tetrameric helical minifilament, which position the C-terminal tai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c244382329a52af5e364281a56394d
https://doi.org/10.1101/2021.10.12.463902
https://doi.org/10.1101/2021.10.12.463902
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86786 (2014)
Aurora-B is the kinase subunit of the Chromosome Passenger Complex (CPC), a key regulator of mitotic progression that corrects improper kinetochore attachments and establishes the spindle midzone. Recent work has demonstrated that the CPC is a microt
Externí odkaz:
https://doaj.org/article/747602403a8c4c81a86a27dd0e2625b7
Autor:
Arthur T. Molines, Joël Lemière, Morgan Gazzola, Ida Emilie Steinmark, Claire H. Edrington, Chieh-Ting Hsu, Paula Real-Calderon, Klaus Suhling, Gohta Goshima, Liam J. Holt, Manuel Thery, Gary J. Brouhard, Fred Chang
Publikováno v:
Developmental Cell
Developmental Cell, 2022, 57 (4), pp.466-479.e6. ⟨10.1016/j.devcel.2022.02.001⟩
Dev Cell
Molines, A T, Lemière, J, Gazzola, M, Steinmark, I E, Edrington, C H, Hsu, C T, Real-Calderon, P, Suhling, K, Goshima, G, Holt, L J, Thery, M, Brouhard, G J & Chang, F 2022, ' Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization ', Developmental Cell, vol. 57, no. 4, pp. 466-479.e6 . https://doi.org/10.1016/j.devcel.2022.02.001
Developmental Cell, 2022, 57 (4), pp.466-479.e6. ⟨10.1016/j.devcel.2022.02.001⟩
Dev Cell
Molines, A T, Lemière, J, Gazzola, M, Steinmark, I E, Edrington, C H, Hsu, C T, Real-Calderon, P, Suhling, K, Goshima, G, Holt, L J, Thery, M, Brouhard, G J & Chang, F 2022, ' Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization ', Developmental Cell, vol. 57, no. 4, pp. 466-479.e6 . https://doi.org/10.1016/j.devcel.2022.02.001
International audience; The cytoplasm is a crowded, visco-elastic environment whose physical properties change according to physiological or developmental states. How the physical properties of the cytoplasm impact cellular functions in vivo remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da6feb7240a994a01061e2d98ab8fa2
https://pubmed.ncbi.nlm.nih.gov/35231424
https://pubmed.ncbi.nlm.nih.gov/35231424
Autor:
Linda Lee, D. Alex Crowder, Andrej Sali, Daniel J. Saltzberg, Atefeh Rafiei, Gary J. Brouhard, David C. Schriemer
Doublecortin (DCX) is a microtubule (MT) associated protein that regulates MT structure and function during neuronal development and mutations in DCX lead to a spectrum of neurological disorders. The structural properties of MT-bound DCX remain poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d933529675ddf82c93d28bb21a6cc664
https://doi.org/10.1101/2021.02.17.431714
https://doi.org/10.1101/2021.02.17.431714
Autor:
Arthur T. Molines, Klaus Suhling, Gohta Goshima, Chieh-Ting Hsu, Manuel Théry, Liam J. Holt, Emilie I. Steinmark, Gary J. Brouhard, Joël Lemière, Morgan Gazzola, Claire H. Edrington, Fred Chang
The cytoplasm is a crowded, visco-elastic environment whose physical properties change according to physiological or developmental states. How the physical properties of the cytoplasm impact cellular functionsin vivoremain poorly understood. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d7506108a57cdd8a8c6b16885a74d28
https://doi.org/10.1101/2020.10.27.352716
https://doi.org/10.1101/2020.10.27.352716
Autor:
Dylan Pelletier, Khanh Huy Bui, Corbin Black, Andrew N. Bayne, Muneyoshi Ichikawa, Nimra Khan, Simon Veyron, Ahmad Abdelzaher Zaki Khalifa, Igor Kurinov, Susanne Bechstedt, Thomas S. McAlear, Jean-François Trempe, Sami Chaaban, Gary J. Brouhard, Nathalie Croteau
Publikováno v:
Structure
The Parkin co-regulated gene protein (PACRG) binds at the inner junction between doublet microtubules of the axoneme, a structure found in flagella and cilia. PACRG binds to the adaptor protein meiosis expressed gene 1 (MEIG1), but how they bind to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debe9c0408b27d3d4459e692128399f0
https://doi.org/10.1016/j.str.2021.01.001
https://doi.org/10.1016/j.str.2021.01.001
Autor:
Nimra Khan, Jean-François Trempe, Dylan Pelletier, Corbin Black, Gary J. Brouhard, Igor Kurinov, Simon Veyron, Muneyoshi Ichikawa, Nathalie Croteau, Sami Chaaban, Ahmad Abdelzaher Zaki Khalifa, Khanh Huy Bui
In human, the Parkin Co-Regulated Gene (PACRG) shares a bidirectional promoter with Parkin, a gene involved in Parkinson’s disease, mitochondrial quality control and inflammation. The PACRG protein is essential to the formation of the inner junctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad40a44e8028318d0a94b584ad16423
Autor:
Klaus Suhling, Chieh-Ting Hsu, I. E. Steinmark, Liam J. Holt, Fred Chang, Gary J. Brouhard, Joël Lemière, Arthur T. Molines, Gohta Goshima, Claire H. Edrington
Publikováno v:
Biophysical Journal. 120:347a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28e31970967a027566f8af04d3593e83
https://doi.org/10.1016/j.bpj.2020.11.2159
https://doi.org/10.1016/j.bpj.2020.11.2159
Publikováno v:
Biophysical Journal. 120:258a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c127b7c3bd00daff2161d04c4e0900
https://doi.org/10.1016/j.bpj.2020.11.1664
https://doi.org/10.1016/j.bpj.2020.11.1664
Autor:
Gary J. Brouhard, Shweta Bendre, Alexander W. Bird, Conrad Hall, Arnaud Rondelet, Nadine Schmidt, Yu-Chih Lin
Publikováno v:
The Journal of Cell Biology
The microtubule depolymerase MCAK influences chromosomal instability (CIN), but what controls its activity remains unclear. Bendre et al. show that GTSE1, a protein found overexpressed in tumors, regulates microtubule stability and chromosome alignme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65451d00bde4774175718e853ffcf03
https://doi.org/10.1083/jcb.201606081
https://doi.org/10.1083/jcb.201606081