Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gary J. Bassill"'
Autor:
Jennifer L Steele, Richard C Stevens, Oscar A Cabrera, Gary J Bassill, Sabrina M Cramer, Felipe Guzman, Anthony P Shuber
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243781 (2020)
The programmable sequence specificity of CRISPR has found uses in gene editing and diagnostics. This manuscript describes an additional application of CRISPR through a family of novel DNA enrichment technologies. CAMP (CRISPR Associated Multiplexed P
Externí odkaz:
https://doaj.org/article/83436e1c01e94d0e8ae071a1f498b6cb
Autor:
Anthony P. Shuber, Gary J. Bassill, Oscar A. Cabrera, Jennifer L. Steele, Richard C. Stevens, Sabrina M. Cramer, Felipe Guzman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0243781 (2020)
PLoS ONE, Vol 15, Iss 12, p e0243781 (2020)
The programmable sequence specificity of CRISPR has found uses in gene editing and diagnostics. This manuscript describes an additional application of CRISPR through a family of novel DNA enrichment technologies. CAMP (CRISPR Associated Multiplexed P
Discovery and characterization of human antibody inhibitors of pregnancy-associated plasma protein-A
Autor:
Andrew E. Nixon, Diana Martik, Gary J. Bassill, Qi-Long Wu, Andrew N. Macintyre, Gary L. McNeil, Shannon Hogan, Daniel J. Sexton, Ting Chen, Csaba Pazmany, Greg Conley
Publikováno v:
bchm. 388:507-512
Pregnancy-associated plasma protein-A (PAPP-A) is a metalloprotease that cleaves insulin-like growth factor-binding proteins (IGFBPs) to release bioactive levels of free insulin-like growth factor. Specific and potent inhibitors of PAPP-A may further
Autor:
Olga V. Nemirovskiy, Marc D. Zack, Aida Abujoub, Malini Viswanathan, Anne-Marie Malfait, Joseph W. Leone, Min Liu, Richard Mazzarella, Robert L. Hills, Micky D. Tortorella, Gary J. Bassill, Arumugam Muruganandam, Elizabeth C. Arner, Kam Fok, Aaron K. Sato, Daniel J. Sexton
Publikováno v:
Journal of Biological Chemistry. 282:11101-11109
ADAMTS-4 and ADAMTS-5 are aggrecanases responsible for the breakdown of cartilage aggrecan in osteoarthritis. Multiple ADAMTS-4 cleavage sites have been described in several matrix proteins including aggrecan, versican, and brevican, but no concise p