Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Gary J Weil"'
Autor:
Catherine M Bjerum, Benjamin G Koudou, Allassane F Ouattara, Daphne Lew, Charles W Goss, Pascal T Gabo, Christopher L King, Peter U Fischer, Gary J Weil, Philip J Budge
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011633 (2023)
BackgroundMoxidectin is a macrocyclic lactone registered for the treatment of human onchocerciasis. The drug has a good safety profile, large volume of distribution and a long elimination half-life. This paper reports tolerability data from the first
Externí odkaz:
https://doaj.org/article/700673892a3b44b5a4de81b30bb18bb0
Autor:
Yashpal S Chhonker, Catherine Bjerum, Veenu Bala, Allassane F Ouattara, Benjamin G Koudou, Toki P Gabo, Abdullah Alshehri, Abdoulaye Meïté, Peter U Fischer, Gary J Weil, Christopher L King, Philip J Budge, Daryl J Murry
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 8, p e0011567 (2023)
Moxidectin (MOX) is a milbemycin endectocide recently approved by the U.S. FDA for the treatment of onchocerciasis in persons at least 12 years of age. MOX has been shown to have a good safety profile in recent clinical trials. The efficacy of MOX fo
Externí odkaz:
https://doaj.org/article/45c8d8f3e90f418f857ef227ccaa3519
Autor:
Sarah E Greene, Yuefang Huang, Kurt C Curtis, Christopher L King, Peter U Fischer, Gary J Weil
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 6, p e0011364 (2023)
BackgroundLymphatic filariasis (LF) is a neglected tropical disease and a major cause of chronic disability. Improved diagnostic tests are needed because of long-term persistence of anti-filarial antibodies or circulating filarial antigenemia after t
Externí odkaz:
https://doaj.org/article/5a8904fecc4a40a9b3dcdc204ed3de95
Autor:
Nicholas O Opoku, Felix Doe, Bettina Dubben, Nicole Fetcho, Kerstin Fischer, Peter U Fischer, Shelter Gordor, Charles W Goss, Michael E Gyasi, Achim Hoerauf, Augustine R Hong, Eric Kanza, Christopher L King, Ruth Laryea, Daphne Lew, Mahmood A Seidu, Gary J Weil
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 5, p e0011365 (2023)
BackgroundOnchocerciasis ("river blindness") has been targeted for elimination. New treatments that kill or permanently sterilize female worms could accelerate this process. Prior studies have shown that triple drug treatment with ivermectin plus die
Externí odkaz:
https://doaj.org/article/d213324823ef4203adc4c4da7521d999
Autor:
Lucia S Di Maggio, Kurt C Curtis, Petra Erdmann-Gilmore, Robert S W Sprung, R Reid Townsend, Gary J Weil, Peter U Fischer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 8, p e0010679 (2022)
Paragonimus kellicotti is a zoonotic lung fluke infection, the agent of North American paragonimiasis, and an excellent model for other Paragonimus infections. The excretory/secretory proteins (ESP) released by parasites and presented at the parasite
Externí odkaz:
https://doaj.org/article/461c3f8cf07042459b6ad539f46a7b37
Autor:
Sarah E Greene, Kerstin Fischer, Young-Jun Choi, Kurt C Curtis, Philip J Budge, Makedonka Mitreva, Christopher L King, Peter U Fischer, Gary J Weil
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 5, p e0010407 (2022)
BackgroundLymphatic filariasis (LF) is a neglected tropical disease caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. The Global Program to Eliminate LF uses mass drug administration (MDA) of anti-filarial drugs
Externí odkaz:
https://doaj.org/article/037ce7b364d84a7baf714c88d408a2f6
Autor:
Livingstone Tavul, Moses Laman, Cade Howard, Bethuel Kotty, Anna Samuel, Catherine Bjerum, Kobie O'Brian, Steven Kumai, Matthew Amuga, Lina Lorry, Zebedee Kerry, Melvin Kualawi, Stephan Karl, Leo Makita, Lucy N John, Sibauk Bieb, James Wangi, Gary J Weil, Charles W Goss, Daniel J Tisch, William Pomat, Christopher L King, Leanne J Robinson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 2, p e0010096 (2022)
BackgroundPapua New Guinea (PNG) has a high burden of lymphatic filariasis (LF) caused by Wuchereria bancrofti, with an estimated 4.2 million people at risk of infection. A single co-administered dose of ivermectin, diethylcarbamazine and albendazole
Externí odkaz:
https://doaj.org/article/2592e7c1c8944b3585c9e863872b3d71
Autor:
Myra Hardy, Josaia Samuela, Mike Kama, Meciusela Tuicakau, Lucia Romani, Margot J Whitfeld, Christopher L King, Gary J Weil, Tibor Schuster, Anneke C Grobler, Daniel Engelman, Leanne J Robinson, John M Kaldor, Andrew C Steer
Publikováno v:
PLoS Medicine, Vol 18, Iss 11, p e1003849 (2021)
BackgroundScabies is a neglected tropical disease hyperendemic to many low- and middle-income countries. Scabies can be successfully controlled using mass drug administration (MDA) using 2 doses of ivermectin-based treatment. If effective, a strategy
Externí odkaz:
https://doaj.org/article/b24fed87401446ae87901a9b844bf36f
Autor:
Kimberly Y Won, Katherine Gass, Marco Biamonte, Daniel Argaw Dagne, Camilla Ducker, Christopher Hanna, Achim Hoerauf, Patrick J Lammie, Sammy M Njenga, Rahmah Noordin, Kapa D Ramaiah, Reda Ramzy, Ronaldo G Carvalho Scholte, Anthony W Solomon, Ashley A Souza, Jordan Tappero, Emily Toubali, Gary J Weil, Steven A Williams, Jonathan D King
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009968 (2021)
As lymphatic filariasis (LF) programs move closer to established targets for validation elimination of LF as a public health problem, diagnostic tools capable of supporting the needs of the programs are critical for success. Known limitations of exis
Externí odkaz:
https://doaj.org/article/f0fc50c7f89d4704aea713148b1f923d
Autor:
Alison Krentel, Nandha Basker, Madsen Beau de Rochars, Joshua Bogus, Daniel Dilliott, Abdel N Direny, Christine Dubray, Peter U Fischer, Adriani Lomi Ga, Charles W Goss, Myra Hardy, Cade Howard, Purushothaman Jambulingam, Christopher L King, Moses Laman, Jean Frantz Lemoine, Shruti Mallya, Leanne J Robinson, Josaia Samuela, Ken B Schechtman, Andrew C Steer, Taniawati Supali, Livingstone Tavul, Gary J Weil
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009002 (2021)
BackgroundMany countries will not reach elimination targets for lymphatic filariasis in 2020 using the two-drug treatment regimen (diethylcarbamazine citrate [DEC] and albendazole [DA]). A cluster-randomized, community-based safety study performed in
Externí odkaz:
https://doaj.org/article/055dce1f8bd048568f5560c3d9f70170