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pro vyhledávání: '"Gary J Marks"'
Publikováno v:
Pharmaceutical Research. 11:283-287
The in vitro Ussing technique was employed to examine transport rates for acetaminophen and arginine across rabbit intestinal tissues. Mannitol and transepithelial conductance were used to monitor the integrity of rabbit intestinal tissues and the ba
Autor:
Jean-Paul Scalart, Philip L. Smith, Panayiotis P. Constantinides, Cindy M. Lancaster, Joseph Marcello, Gary J. Marks, Harma Ellens
Publikováno v:
Pharmaceutical Research. 11:1385-1390
We developed self-emulsifying water-in-oil (w/o) microemulsions incorporating medium-chain glycerides and measured their conductance, viscosity, refractive index and particle size. Formulation of Calcein (a water-soluble marker molecule, MW = 623), o
Publikováno v:
International Journal of Pharmaceutics. 98:83-92
Previous studies have demonstrated carrier-mediated cephalexin (CPX) transport in rat jejunum under basal conditions. The purpose of this study was to compare fluxes of cephalexin (CPX) and benzylpenicillin (BZP) across rabbit intestine to those repo
Autor:
Gary J Marks, Kei-Lai L Fong, Sylvia T. Hoffstein, Timothy K. Hart, Glenn F. Rush, Peter J. Bugelski
Publikováno v:
Thrombosis and Haemostasis. 63:251-258
SummaryThe uptake and internalization of tissue-type plasminogen activator (t-PA) by freshly isolated rat hepatocytes was investigated. Electron microscopic examination of the uptake of t-PA-colloidal gold conjugates (t-PA-gold) by isolated rat hepat
Autor:
Luciano Ramos, Peter J. Bugelski, Timothy K. Hart, Oka Melvin Susumu, Mitchell E. Reff, Gary J Marks, Doris Gennaro, Sylvia T. Hoffstein
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 198(1)
Tissue-type plasminogen activator (tPA) is a serine protease which cleaves plasminogen to its active form, plasmin. tPA plays a physiologic role in hemostasis, wound healing, and embryogenesis. Therapeutically, recombinant human tPA is used as a thro