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pro vyhledávání: '"Gary J Lehr"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 33:627-637
A gradient elution LC method was developed to separate methoxsalen from three of its known impurities: isopimpinellin, bergapten, and ammidin. The method employs a methanol–6%THF (aq) mobile phase, phenyl column, and detection at 254 nm. The gradie
Autor:
Gary J Lehr
Publikováno v:
Journal of AOAC INTERNATIONAL. 79:1288-1293
An isocratic, reversed-phase liquid chromatographic (LC) method was developed for simultaneous determination of diphenoxylate hydrochloride (I) and atropine sulfate (II) in pharmaceutical products. Analysis is conducted on a Spherisorb CN column (5
Publikováno v:
Journal of AOAC INTERNATIONAL. 78:339-342
A simple and specific liquid chromatographic method was developed for the determination of atropine in nerve gas antidotes and several other dosage forms. The method is also used simultaneously to quantitate phenol, an antimicrobial agent present in
Publikováno v:
Journal of AOAC INTERNATIONAL. 78:413-418
A purge-and-trap gas chromatographic-mass spectrometric procedure is presented for determination of trace levels of benzene in denture adhesives and their raw materials. The limit of quantitation is 10 ppb, reproducibility is ± 10%, and recoveries o
Autor:
Gary J Lehr, Stella M Yuen
Publikováno v:
Journal of AOAC INTERNATIONAL. 74:461-464
A specific liquid chromatographic method was developed for determination of clidinium bromide and clidinium bromidechlordiazepoxide hydrochloride combinations in capsules. The procedure uses a Partisil 10 ODS-3 column and a mobile phase consisting of
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 19(3-4)
Twenty-two lots of recently synthesized trimethoprim drug substance, from five different manufacturers, in three different countries of origin, China, Israel and the United States, were investigated for the presence of impurities. A liquid chromatogr