Zobrazeno 1 - 10
of 67 837
pro vyhledávání: '"Gary J"'
Publikováno v:
Addiction Science & Clinical Practice, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background Opioid use disorder (OUD) remains a significant public health issue as the number of opioid-related overdose deaths continues to reach new highs each year. Buprenorphine/Naloxone is a medication that has been shown to be highly ef
Externí odkaz:
https://doaj.org/article/1a051045605d484ca24cdb394aae20e6
Publikováno v:
Bone & Joint Open, Vol 5, Iss 10, Pp 937-943 (2024)
Aims: The aim of this study was to determine whether obesity had a detrimental effect on the long-term performance and survival of medial unicompartmental knee arthroplasties (UKAs). Methods: This study reviewed prospectively collected functional out
Externí odkaz:
https://doaj.org/article/eb2d078558da4075a76612acc6fb97b7
Autor:
Sabha Asghar, Gary J. Litherland, John J. Cole, Iain B. McInnes, R. M. D. Meek, John C. Lockhart, Carl S. Goodyear, Anne Crilly
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Small extracellular vesicles (sEV) derived from synovial fibroblasts (SF) represent a novel molecular mechanism regulating cartilage erosion in osteoarthritis (OA). However, a comprehensive evaluation using disease relevant cells
Externí odkaz:
https://doaj.org/article/3b5cf59e34534e7c8772f11be34ab22f
Publikováno v:
npj Quantum Information, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract One of the fundamental tasks in quantum information theory is quantum data compression, which can be realized via quantum autoencoders that first compress quantum states to low-dimensional ones and then recover to the original ones with a re
Externí odkaz:
https://doaj.org/article/feff405012bd4836949d71e0ebccc690
Autor:
Abhinav Thakral, John JW. Lee, Tianzhichao Hou, Katrina Hueniken, Tom Dudding, Mark Gormley, Shama Virani, Andrew Olshan, Brenda Diergaarde, Andrew R. Ness, Tim Waterboer, Karl Smith-Byrne, Paul Brennan, D. Neil Hayes, Eleanor Sanderson, M. Catherine Brown, Sophie Huang, Scott V. Bratman, Anna Spreafico, John De Almeida, Joel C. Davies, Laura Bierut, Gary J. Macfarlane, Pagona Lagiou, Areti Lagiou, Jerry Polesel, Antonio Agudo, Laia Alemany, Wolfgang Ahrens, Claire M. Healy, David I. Conway, Mari Nygard, Cristina Canova, Ivana Holcatova, Lorenzo Richiardi, Ariana Znaor, David P. Goldstein, Rayjean J. Hung, Wei Xu, Geoffrey Liu, Osvaldo Espin-Garcia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are recognized as distinct entities. There remains uncertainty surrounding the causal effects of smoking and alcohol on the development of these two cancer types. He
Externí odkaz:
https://doaj.org/article/d3d477a5f0674925ba9467f628ee8ad5
Autor:
Jinzhou Peng, Dengfeng Li, Simon W. Poulton, Gary J. O’Sullivan, David Chew, Yu Fu, Xiaoming Sun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Marine phosphatization events cause episodic carbonate fluorapatite (CFA) precipitation on seamounts, and are commonly linked to growth hiatuses in ferromanganese (Fe-Mn) crusts. However, the complete record of these events and their paleoen
Externí odkaz:
https://doaj.org/article/b15852028e964503a6eeb2e94e5a15c0
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 80, Iss 8, Pp 863-866 (2024)
The aryl diester compound, 2-methyl-1,4-phenylene bis(3,5-dibromobenzoate), C21H12Br4O4, was synthesized by esterification of methyl hydroquinone with 3,5-dibromobenzoic acid. A crystalline sample was obtained by cooling a sample of the melt (m.p. =
Externí odkaz:
https://doaj.org/article/98ab9cb383c64135abb7285dc15d3e7f
Autor:
Rania M. Mohamed, Bikash Panthi, Beatriz E. Adrada, Medine Boge, Rosalind P. Candelaria, Huiqin Chen, Mary S. Guirguis, Kelly K. Hunt, Lei Huo, Ken-Pin Hwang, Anil Korkut, Jennifer K. Litton, Tanya W. Moseley, Sanaz Pashapoor, Miral M. Patel, Brandy Reed, Marion E. Scoggins, Jong Bum Son, Alastair Thompson, Debu Tripathy, Vicente Valero, Peng Wei, Jason White, Gary J. Whitman, Zhan Xu, Wei Yang, Clinton Yam, Jingfei Ma, Gaiane M. Rauch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Triple-negative breast cancer (TNBC) is often treated with neoadjuvant systemic therapy (NAST). We investigated if radiomic models based on multiparametric Magnetic Resonance Imaging (MRI) obtained early during NAST predict pathologic comple
Externí odkaz:
https://doaj.org/article/6a9d5085faa94e07a2d7d1b1c2688f40
Autor:
Paola Sebastiani, Stefano Monti, Michael S. Lustgarten, Zeyuan Song, Dylan Ellis, Qu Tian, Michaela Schwaiger-Haber, Ethan Stancliffe, Anastasia Leshchyk, Meghan I. Short, Andres V. Ardisson Korat, Anastasia Gurinovich, Tanya Karagiannis, Mengze Li, Hannah J. Lords, Qingyan Xiang, Megan M. Marron, Harold Bae, Mary F. Feitosa, Mary K. Wojczynski, Jeffrey R. O’Connell, May E. Montasser, Nicole Schupf, Konstantin Arbeev, Anatoliy Yashin, Nicholas Schork, Kaare Christensen, Stacy L. Andersen, Luigi Ferrucci, Noa Rappaport, Thomas T. Perls, Gary J. Patti
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114913- (2024)
Summary: Metabolites that mark aging are not fully known. We analyze 408 plasma metabolites in Long Life Family Study participants to characterize markers of age, aging, extreme longevity, and mortality. We identify 308 metabolites associated with ag
Externí odkaz:
https://doaj.org/article/c744c40c4a184bd995de8390a0fca998
Autor:
Jiameng Sun, Yiming Zhang, Joshua A. Adams, Cassandra B. Higgins, Shannon C. Kelly, Hao Zhang, Kevin Y. Cho, Ulysses G. Johnson, Benjamin M. Swarts, Shun-Ichi Wada, Gary J. Patti, Leah P. Shriver, Brian N. Finck, Erik D. Herzog, Brian J. DeBosch
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114865- (2024)
Summary: Organisms integrate circadian and metabolic signals to optimize substrate selection to survive starvation, yet precisely how this occurs is unclear. Here, we show that hepatocyte Period 1 (Per1) is selectively induced during fasting, and mic
Externí odkaz:
https://doaj.org/article/f3f84b6930c6468d8267aafa1547506a