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pro vyhledávání: '"Gary Grumbling"'
Autor:
Victor B. Strelets, Gary Grumbling
Publikováno v:
Nucleic Acids Research
FlyBase (http://flybase.org/) is a database of genetic and genomic data on the model organism Drosophila melanogaster and the entire insect family Drosophilidae. The FlyBase Consortium curates, annotates, integrates and maintains a wide variety of da
Autor:
Gary Grumbling, Allen Shearn, Cynthia Bennington-Mathias, Bruce C. Schnepp, Amanda Simcox, Evelyn Hersperger
Publikováno v:
Developmental Biology. 177(2):475-489
vein 1 ( vn 1 ) mutants lack portions of longitudinal wing vein 4 and the anterior crossvein. Stronger alleles, originally called defective dorsal discs, show vn is also required for the growth of the wing and haltere discs, as mutants for these alle
Autor:
Amanda Simcox, Timothy Donaldson, Ben-Zion Shilo, Ronen Schweitzer, Bruce C. Schnepp, Gary Grumbling, Stephen Ostrowski
Publikováno v:
Genesdevelopment. 12(7)
In Drosophila the function of the epidermal growth factor (EGF) receptor is modulated zygotically by three EGF-like proteins: Spitz (Spi), which is a potent activator; Vein (Vn), which is a moderate activator; and Argos (Aos), which is an inhibitor.
Publikováno v:
Genesdevelopment. 10(18)
The activation signal from tyrosine kinase receptors, such as the epidermal growth factor receptor (EGFR), is relayed via a highly conserved intracellular pathway involving Ras, Raf, and MAPK. In Drosophila, the EGFR and components of the intracellul
Publikováno v:
Developmental Biology. (1):243-259
Signaling by the Drosophila EGF receptor (DER) is modulated by four known EGF-like proteins: the agonists Vein (Vn), Spitz (Spi), and Gurken (Grk) and the antagonist Argos (Aos). DER is broadly expressed and thus tissue-specific regulation of ligand
Publikováno v:
Journal of Biomedical Semantics
Background Anatomy ontologies are query-able classifications of anatomical structures. They provide a widely-used means for standardising the annotation of phenotypes and expression in both human-readable and programmatically accessible forms. They a