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The CSF-1 receptor is a protein-tyrosine kinase that has been shown to undergo regulated intramembrane proteolysis, or RIPping. Here, we have compared receptor downregulation and RIPping in response to CSF-1 and TPA. Our studies show that CSF-1 is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4356a15ea7f2f53e6ac5d072fe9d35
https://doi.org/10.1016/j.febslet.2007.10.031

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Purification and Identification of Protein-Tyrosine Kinase-binding Proteins Using Synthetic Phosphopeptides as Affinity Reagents

Autor: Jeremy Copp, Peter van der Geer, Kevin Wilhelmsen, Ross C. Hoffman, Gary Glenn, Philip W. Tucker

Publikováno v: Molecular & Cellular Proteomics. 3:887-895

Protein-tyrosine kinases are known regulators of cell division that have been implicated in the onset of a variety of malignancies. They act through cellular signaling proteins that bind to specific autophosphorylation sites. To find out whether thes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19adb5214346518a26f08973a64ed3c
https://doi.org/10.1074/mcp.m400062-mcp200

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Preparation of Protein Samples for Mass Spectrometry and N-Terminal Sequencing

Autor: Gary Glenn

The preparation of protein samples for mass spectrometry and N-terminal sequencing is a key step in successfully identifying proteins. Mass spectrometry is a very sensitive technique, and as such, samples must be prepared carefully since they can be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56db02c4f681343d2b5e918acc8fb311
https://doi.org/10.1016/b978-0-12-420070-8.00003-9

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