Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gary Gang Chen"'
Autor:
Glenda MacQueen, Benicio N. Frey, Daniel J. Müller, Roumen Milev, Claudio N. Soares, Faranak Farzan, Sidney H. Kennedy, Sagar V. Parikh, Francesco Leri, Laura M. Fiori, Jean-François Théroux, Peter Giacobbe, Gary Gang Chen, Pierre Blier, Zahia Aouabed, Qingqin Li, Susan Rotzinger, Jane A. Foster, Raoul Belzeaux, Rudolf Uher, Raymond W. Lam, Chelsey Ju, Gustavo Turecki
Publikováno v:
Translational Psychiatry, Vol 9, Iss 1, Pp 1-12 (2019)
Translational Psychiatry
Translational Psychiatry
Major depressive disorder (MDD) is primarily treated with antidepressants, yet many patients fail to respond adequately, and identifying antidepressant response biomarkers is thus of clinical significance. Some hypothesis-driven investigations of epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9306905dba14a885b7977d583ee0dd8c
https://doi.org/10.1038/s41398-019-0589-0
https://doi.org/10.1038/s41398-019-0589-0
Autor:
Claudio N. Soares, Roumen Milev, Faranak Farzan, Daniel J. Müller, Sidney H. Kennedy, Rudolf Uher, Jean-François Théroux, Francesco Leri, Laura M. Fiori, Raymond W. Lam, Qingqin Li, Chelsey Ju, Susan Rotzinger, Raoul Belzeaux, Sagar V. Parikh, Pierre Blier, Peter Giacobbe, Glenda MacQueen, Jane A. Foster, Gustavo Turecki, Benicio N. Frey, Zahia Aouabed, Gary Gang Chen
Publikováno v:
SSRN Electronic Journal.
Background: Major depressive disorder (MDD) is primarily treated with antidepressants, yet many patients fail to respond to adequate trials. Understanding who is likely to respond to antidepressant treatment and/or what mediates this response is of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645bfc23fd86b4d9df5bc764efa0d0fc
https://doi.org/10.2139/ssrn.3234907
https://doi.org/10.2139/ssrn.3234907
Autor:
Luis B. Barreiro, Jeffrey A. Gross, Gary Gang Chen, Alain Pacis, Drupals M, Pierre-Eric Lutz, Gustavo Turecki
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Nature Pub. Group, 2017, 7, pp.e1119. ⟨10.1038/tp.2017.93⟩
Translational Psychiatry, Nature Pub. Group, 2017, 7, pp.e1119. ⟨10.1038/tp.2017.93⟩
International audience; 5-Hydroxymethylcytosine (5hmC) is a recently characterized epigenetic mark that is particularly abundant in brain tissue and that regulates gene transcription. We have recently begun to understand the important role of 5hmC in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae6af1f3ab07468d98543e9bd1b562f
https://hal.archives-ouvertes.fr/hal-02437488/file/Gross_5hmC-MDD+suicide_Transl-Psych-2017.pdf
https://hal.archives-ouvertes.fr/hal-02437488/file/Gross_5hmC-MDD+suicide_Transl-Psych-2017.pdf
Publikováno v:
Journal of Mass Spectrometry. 45:560-565
The group of biologically important amines includes putrescine, spermidine and spermine, as well as agmatine, which is a guanidino-amine. There is considerable evidence supporting a role of these amines in the etiology and pathology of mental disorde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc0674a9c1db5697f3af7262866e583
https://doi.org/10.1002/jms.1742
https://doi.org/10.1002/jms.1742
Autor:
Alain Gratton, Laura M. Fiori, Orval A. Mamer, Naguib Mechawar, Gustavo Turecki, Gary Gang Chen, Luc Moquin
Publikováno v:
Neuropsychopharmacology. 35:1477-1484
Recent studies have implicated alterations in the expression of polyamine-related genes in the brains of suicide completers including widespread downregulation of spermidine/spermine N1-acetyltransferase, the key enzyme in polyamine catabolism, sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc93aa6f3a508efd56bcf27b7081263
https://doi.org/10.1038/npp.2010.17
https://doi.org/10.1038/npp.2010.17
Autor:
Gary Gang Chen, Gustavo Turecki, Cristiana Cruceanu, Naguib Mechawar, Susana G. Torres-Platas
Publikováno v:
Brain, behavior, and immunity. 42
Despite increasing evidence supporting the neuroinflammatory theory of depression, little is known about cerebral macrophages in individuals suffering from major depression. In the present study, we investigated the morphology and distribution of cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e09d2c64e4743d49317cacb8e8edf98
https://pubmed.ncbi.nlm.nih.gov/25128842
https://pubmed.ncbi.nlm.nih.gov/25128842
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 720
There is considerable evidence supporting a role of the polyamine system in the etiology and pathology of mental disorders. Changes in the expression and activity of polyamine anabolic/catabolic enzymes, as well as in the levels of individual polyami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92a94066efb32cd53a96ac69e31d8afb
https://pubmed.ncbi.nlm.nih.gov/21318890
https://pubmed.ncbi.nlm.nih.gov/21318890
Publikováno v:
Methods in Molecular Biology ISBN: 9781617790331
There is considerable evidence supporting a role of the polyamine system in the etiology and pathology of mental disorders. Changes in the expression and activity of polyamine anabolic/catabolic enzymes, as well as in the levels of individual polyami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3b02cca6a739abcd4e4f38f5a86a859
https://doi.org/10.1007/978-1-61779-034-8_27
https://doi.org/10.1007/978-1-61779-034-8_27
Autor:
Gary Gang Chen, Fiori, Laura M., Moquin, Luc, Gratton, Alain, Mamer, Orval, Mechawar, Naguib, Turecki, Gustavo
Publikováno v:
Neuropsychopharmacology; Jun2010, Vol. 35 Issue 7, p1477-1484, 8p, 1 Chart, 2 Graphs