Zobrazeno 1 - 10 of 58 pro vyhledávání: '"Gary G. Kay"'
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Elektronická kniha
Aeromedical Psychology
Autor: Carrie H. Kennedy, Gary G. Kay
Aeromedical psychology is that branch of psychology pertaining to the assessment, selection and evaluation of aviation personnel. This book, Aeromedical Psychology, is designed to provide the means for a variety of clinicians to carry out sound asses
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A randomized, multicenter trial assessing the effects of rapastinel compared to ketamine, alprazolam, and placebo on simulated driving performance
Autor: Thomas Hochadel, Antonia Periclou, J. Christopher Stein, Jonathan Rojo, Shengfang Su, Gary G. Kay, Ramesh Boinpally
Publikováno v: Clinical and Translational Science, Vol 15, Iss 1, Pp 255-266 (2022)
Clinical and Translational Science
N‐methyl‐D‐aspartate ionotropic glutamatergic receptor (NMDAR) modulators, including rapastinel and ketamine, elicit rapid and sustained antidepressant responses in patients with treatment‐resistant major depressive disorder. This phase I, ra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574d95f5c8dbc91edf4122d12234cc53
https://doi.org/10.1111/cts.13145
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3
Simulated driving performance in healthy adults after night-time administration of 20 mg tasimelteon
Autor: Gunther Birznieks, Rosarelis Torres, Changfu Xiao, Michaela Fisher, Mihael H. Polymeropoulos, Christos Polymeropoulos, Gary G Kay
Publikováno v: Journal of sleep research. 31(1)
An impairment in next day driving performance has been reported for almost every drug currently United States Food and Drug Administration (FDA) approved for improvement of sleep in chronic and transient insomnia. Tasimelteon, a melatonin receptor ag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9169f6dd6a113057cd301fe842e393
https://pubmed.ncbi.nlm.nih.gov/34152055
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4
Effects of lasmiditan on simulated driving performance: Results of two randomized, blinded, crossover studies with placebo and active controls
Autor: Erin G Doty, Darren Wilbraham, Gary G. Kay, Max Tsai, Eric M. Pearlman, Ellen B. Dennehy, Paul Berg
Publikováno v: Human Psychopharmacology
Objective To evaluate the impact of lasmiditan, an oral, centrally‐penetrant, selective serotonin 1F (5‐HT1F) receptor agonist developed for the acute treatment of migraine, on simulated driving. Methods Healthy adult volunteers enrolled in two r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694c13bb7c9a54d75d061e9f2b36bf01
https://doi.org/10.1002/hup.2732
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5
Next-day residual effects of gabapentin, diphenhydramine, and triazolam on simulated driving performance in healthy volunteers: a phase 3, randomized, double-blind, placebo-controlled, crossover trial
Autor: Russell Rosenberg, Gary G. Kay, Shyamalie Jayawardena, Mark A. Wingertzahn, Howard Schwartz
Publikováno v: Human Psychopharmacology: Clinical and Experimental. 31:217-226
Objective Next-day residual effects of a nighttime dose of gabapentin 250 mg were evaluated on simulated driving performance in healthy participants in a randomized, placebo-controlled, double-blind, multicenter, four-period crossover study that incl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06c2fed4c5b137ab9638e369932df25c
https://doi.org/10.1002/hup.2530
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6
A randomized, crossover, placebo-controlled clinical trial to assess the sensitivity of the CRCDS Mini-Sim to the next-day residual effects of zopiclone
Autor: Ingeborg Heirman, Arthur A. Simen, Kim Bleys, Jang-Ho Cha, Chan R. Beals, T Laethem, Cynthia Gargano, Arie Struyk, Aubrey Stoch, Melissa Drexel, Gary G. Kay, Thomas Hochadel, Lien Gheyle, An Bautmans
Publikováno v: Therapeutic Advances in Drug Safety. 6:86-97
Objectives: We sought to validate Cognitive Research Corporation’s Driving Simulator (CRCDS Mini-Sim) for studies of drug safety with respect to driving ability. Methods: A total of 30 healthy subjects were randomized to receive placebo or 7.5 mg z
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb029fcc6ff8cc14aae6ae2ded86a090
https://doi.org/10.1177/2042098615579314
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9
Early-stage comparative effectiveness: Randomized controlled trial with histamine inverse agonist MK-7288 in excessive daytime sleepiness patients
Autor: Christopher Lines, M. Gail Murphy, Chantal Mahon, John J. Renger, Hong Sun, John A. Wagner, Kate Mostoller, W. Joseph Herring, Catherine MacLeod, Gary G. Kay, Lingling Han, Valerie Schulz, Junshui Ma, Kevin R. Brown, Laura B. Rosen
Publikováno v: The Journal of Clinical Pharmacology. 53:1294-1302
Histaminergic neurons are regulators of the sleep-wake cycle. We evaluated the alerting effects of MK-7288 (10, 20 mg), a novel histamine-3 receptor inverse agonist (H3RIA), along with modafinil (200 mg), a standard treatment, in a randomized, double
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::691bde734118828ca575e167420b3290
https://doi.org/10.1002/jcph.182
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10
Effects of Armodafinil on Simulated Driving and Self-Report Measures in Obstructive Sleep Apnea Patients prior to Treatment with Continuous Positive Airway Pressure
Autor: Neil T. Feldman, Gary G Kay
Publikováno v: Journal of Clinical Sleep Medicine. :445-454
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) has been associated with an increased risk of motor vehicle crashes. This driving risk can be reduced (≥ 50%) by treatment with continuous positive airway pressure (CPAP). However residual excessive d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587b870e8173933f6337b5f799ecef46
https://doi.org/10.5664/jcsm.2662
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