Efficacy and safety of aripiprazole vs. haloperidol for long-term maintenance treatment following acute relapse of schizophrenia

Autor: A. Saha, Teresa A. Pigott, William H. Carson, Gary G. Ingenito, Siegfried Kasper, Robert D. McQuade, Mirza Ali, Donald G. Archibald, Ronald N. Marcus, Mark N. Lerman

Publikováno v: The International Journal of Neuropsychopharmacology. 6:325-337

Aripiprazole is a novel atypical antipsychotic for the treatment of schizophrenia. It is a D2 receptor partial agonist with partial agonist activity at 5-HT1A receptors and antagonist activity at 5-HT2A receptors. The long-term efficacy and safety of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5620007a8907efa154c08776bea22b
https://doi.org/10.1017/s1461145703003651

Efficacy and Safety of Aripiprazole and Haloperidol Versus Placebo in Patients With Schizophrenia and Schizoaffective Disorder

Autor: Robert D. McQuade, Dan L. Zimbroff, William H. Carson, A. Saha, John M. Kane, Mirza Ali, Gary G. Ingenito

Publikováno v: The Journal of Clinical Psychiatry. 63:763-771

Background: Aripiprazole is an investigational agent for treating schizophrenia that has a novel pharmacologic profile. The present study investigated the efficacy, safety, and tolerability of aripiprazole and haloperidol compared with placebo. Metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3df6cec9381494fa21bd8001497184e
https://doi.org/10.4088/jcp.v63n0903

Switching patients to aripiprazole from other antipsychotic agents: a multicenter randomized study

Autor: Daniel E. Casey, William H. Carson, Amy Liebeskind, Mirza Ali, Gary G. Ingenito, A. Saha, Darlene Jody

Publikováno v: Psychopharmacology. 166(4)

Switching patients from one antipsychotic to another can lead to tolerability problems or transient symptom exacerbations. It is important to compare switching strategies to determine which methods produce the best possible patient outcomes. To inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63da5784262454767b3175651c495a7
https://pubmed.ncbi.nlm.nih.gov/12610718

Amifampridine safety and efficacy in spinal muscular atrophy ambulatory patients: a randomized, placebo-controlled, crossover phase 2 trial.

Autor: Bonanno S; Neuroimmunology and Neuromuscular Disease Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy., Giossi R; Neuroimmunology and Neuromuscular Disease Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.; Department of Oncology and Onco-Hematology, Postgraduate School of Clinical Pharmacology and Toxicology, University of Milan, Milan, Italy., Zanin R; Developmental Neurology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Porcelli V; Department of Clinical Research and Innovation, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Iannacone C; SPARC Consulting, Milan, Italy., Baranello G; Developmental Neurology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Developmental Neuroscience Research and Teaching Department, Faculty of Population Health Sciences, Dubowitz Neuromuscular Centre, UCL Great Ormond Street Institute of Child Health, London, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Ingenito G; Catalyst Pharmaceuticals, Inc., Coral Gables, USA., Iyadurai S; Catalyst Pharmaceuticals, Inc., Coral Gables, USA.; Johns Hopkins All Children's Hospital, St Petersburg, FL, 33701, USA., Stevic Z; Faculty of Medicine, Neurology Clinic, University Clinical Center of Serbia, University of Belgrade, Dr Subotica 6, 11000, Belgrade, Serbia., Peric S; Faculty of Medicine, Neurology Clinic, University Clinical Center of Serbia, University of Belgrade, Dr Subotica 6, 11000, Belgrade, Serbia., Maggi L; Neuroimmunology and Neuromuscular Disease Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy. lorenzo.maggi@istituto-besta.it.

Publikováno v: Journal of neurology [J Neurol] 2022 Nov; Vol. 269 (11), pp. 5858-5867. Date of Electronic Publication: 2022 Jun 28.

Two-Dimensional Proton Magnetic Resonance Spectroscopy versus J-Editing for GABA Quantification in Human Brain: Insights from a GABA-Aminotransferase Inhibitor Study.

Autor: Prescot AP; Department of Radiology and Imaging Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA. andrew.prescot@utah.edu., Prisciandaro JJ; Department of Psychiatry and Behavioral Sciences, Addiction Sciences Division, Medical University of South Carolina, Charleston, SC, USA., Miller SR; Catalyst Pharmaceuticals Inc, Coral Gables, FL, USA., Ingenito G; Catalyst Pharmaceuticals Inc, Coral Gables, FL, USA., Kondo DG; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA.; Rocky Mountain Mental Illness Research, Education, and Clinical Center (MIRECC), Department of Veterans Affairs Medical Center, Salt Lake City, UT, USA., Renshaw PF; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA.; Rocky Mountain Mental Illness Research, Education, and Clinical Center (MIRECC), Department of Veterans Affairs Medical Center, Salt Lake City, UT, USA.

Publikováno v: Scientific reports [Sci Rep] 2018 Sep 04; Vol. 8 (1), pp. 13200. Date of Electronic Publication: 2018 Sep 04.