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pro vyhledávání: '"Gary Fred Musso"'
Publikováno v:
Bioconjugate Chemistry. 3:88-90
Synthetic approaches for obtaining biotinyl aldehydes are described. While such aldehydes have limited shelflife, the acetal derivative, N-[6-(ethylenedioxy)hexyl]biotinamide, IX, was found to be indefinitely stable upon storage at -20 degrees C. Mil
Design, Synthesis, and Analysis of Secondary Structure Based Vasoactive Intestinal Peptide Analogues
Publikováno v:
Annals of the New York Academy of Sciences. 527:660-662
Autor:
Gary Fred Musso, Soumitra S. Ghosh
Publikováno v:
Nucleic acids research. 15(13)
Coupling efficiencies for the covalent attachment of oligonucleotides (17-29 bases in length) to solid supports derivatized with alkyl-amino and -carboxylic functionalities have been determined. Attachment efficiencies of 60-80% were obtained for coa
Autor:
Gary Fred Musso, Emil Thomas Kaiser, Sally Provow, Thomas C. Ryskamp, Saraswathi Patthi, Gonul Velicelebi
Publikováno v:
Biochemistry. 27(21)
Several VIP analogues have been designed on the basis of the hypothesis that the region from residue 6 to residue 28 forms a pi-helical structure when bound to membrane receptors. An empirical approach for the design and construction of analogues bas