Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Gary Fiskum"'
Publikováno v:
Journal of Central Nervous System Disease, Vol 15 (2023)
Background Mild traumatic brain injury (mTBI) generally resolves within weeks. However, 15-30% of patients present persistent pathological and neurobehavioral sequelae that negatively affect their quality of life. Hyperhomocysteinemia (HHCY) is a neu
Externí odkaz:
https://doaj.org/article/6fe81b7ac0584fb7b34e591e36afe50d
Publikováno v:
Metabolites, Vol 12, Iss 8, p 710 (2022)
Traumatic brain injury (TBI) is leading cause of morbidity in young children. Acute dysregulation of oxidative glucose metabolism within the first hours after injury is a hallmark of TBI. The developing brain relies on ketones as well as glucose for
Externí odkaz:
https://doaj.org/article/1525dc65d6794952b70ee3c29c978a35
Publikováno v:
Journal of Central Nervous System Disease, Vol 13 (2021)
Background: United States service members injured in combat theatre are often aeromedically evacuated within a few days to regional military hospitals. Animal and epidemiological research indicates that early exposure to flight hypobaria may worsen b
Externí odkaz:
https://doaj.org/article/0346ff5182de4ac7a88824084119f494
Autor:
Stephen J. DeVience, Xin Lu, Julie L. Proctor, Parisa Rangghran, Juliana A. Medina, Elias R. Melhem, Rao P. Gullapalli, Gary Fiskum, Dirk Mayer
Publikováno v:
Metabolites, Vol 11, Iss 6, p 335 (2021)
Hyperpolarized magnetic resonance spectroscopic imaging (MRSI) of [1-13C]pyruvate metabolism has previously been used to assess the effects of traumatic brain injury (TBI) in rats. Here, we show that MRSI can be used in conjunction with dichloroaceta
Externí odkaz:
https://doaj.org/article/6146bbe07f984682bc09ca9590685fc9
Autor:
Pascaline Clerc, Christina A Young, Evan A Bordt, Alina M Grigore, Gary Fiskum, Brian M Polster
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79982 (2013)
Extracellular glutamate is elevated following brain ischemia or trauma and contributes to neuronal injury. We tested the hypothesis that magnesium sulfate (MgSO4, 3 mM) protects against metabolic failure caused by excitotoxic glutamate exposure. Rat
Externí odkaz:
https://doaj.org/article/942bf401d18342409a0a74771661ef05
Publikováno v:
Mediators of Inflammation, Vol 2, Iss 7, Pp S51-S56 (1993)
The purpose of this study was to determine if free or esterified carnitine could alter fatty acid metabolism and ameliorate sepsis in lipopolysaccharide (LPS)-treated rats. Throughout a 96 h observation post-LPS, i.p. administration of both markedly
Externí odkaz:
https://doaj.org/article/ec5c086c1d01484a933ddb585765efd5
Autor:
Andrew O. Suen, Fengqian Chen, Sheng Wang, Ziyi Li, Jing Zhu, Yang Yang, Olivia Conn, Kerri Lopez, Ping Cui, Laurence Wechsler, Alan Cross, Gary Fiskum, Rosemary Kozar, Peter Hu, Catriona Miller, Lin Zou, Brittney Williams, Wei Chao
Publikováno v:
J Immunol
Severe traumatic injury leads to marked systemic inflammation and multiorgan injury. Endogenous drivers such as extracellular nucleic acid may play a role in mediating innate immune response and the downstream pathogenesis. Here, we explored the role
Autor:
Alan S. Cross, Adrienne R Kambouris, Kerri Lopez, Jessica C Allen, Gideon Wolf, Scott M Baliban, Jerod Brammer, Raphael Simon, Myeongjin Choi, Gary Fiskum, Wei Chao, Nevil J. Singh, Catriona Miller
Publikováno v:
Journal of Burn Care & Research. 43:792-801
The World Health Organization estimates ~180,000 deaths occur annually from burn-related injuries. Many victims who survive the initial burn trauma succumb to bacterial infections that lead to sepsis during treatment. Although advancements in burn ca
Autor:
Christine R. Hoch, N. Jennifer Klinedinst, Karen Larimer, Cynthia Renn, Gary Fiskum, Stephen S. Gottlieb
Publikováno v:
Journal of Cardiovascular Nursing.
Autor:
Yunbo Ke, Julie Proctor, Chenou Zhang, Juliana Medina, Catriona Miller, Kim Junhyun, Thomas Grisom, Anna Birukova, Gary Fiskum, Konstantin Birukov
Publikováno v:
The FASEB Journal. 36