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pro vyhledávání: '"Gary F. Cooper"'
ChemInform Abstract: Synthesis of Substituted 1,3-Propanesultams from N-Substituted 2-Amino Alcohols
Autor:
Gary F. Cooper
Publikováno v:
ChemInform. 23
Substituted 1,3-propanesultams (isothiazolidine 1,1-dioxides) 3a-c have been prepared via butyllithium-mediated cyclization of the N,O-dimesylates 2a-c of N-substituted 2-amino alcohols 1 a-c
Autor:
Gabriel Garay, A.Peter Roszkowski, Angel Guzman, Humberto Carpio, J.A. Mendez, Joseph M. Muchowski, Wren Douglas L, John H Fried, Horn Albert R Van, John A Edwards, Gary F. Cooper
Publikováno v:
Prostaglandins. 33:169-180
In order to improve the modest oral activity of PGE 2 as an inhibitor of gastric acid secretion, analogs were prepared and tested orally in histamine-challenged rats. Insertion of a double bond at C-4, resulting in the 4,5-allene analog of PGE 1 , ga
Autor:
Gary F. Cooper
Publikováno v:
Steroids. 51:459-464
A convenient synthesis of 5,17-dihydroxy-5α,17α-19-norpregn-20-yn-3-one in multigram quantities from norethindrone is reported. Confirmation of the structural assignment of this major photodegradation product of norethindrone is thus made.
Publikováno v:
The Journal of Organic Chemistry. 37:1947-1950
Autor:
Gary F. Cooper, Josef Fried
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 70(5)
High-resolution pulsed Fourier-transform nuclear magnetic resonance spectroscopy at 22.63 MHz was used to observe the proton-decoupled natural-abundance 13 C nuclear magnetic resonance spectra of CDCl 3 solutions of the methyl esters of prostaglandin