Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gary C. Visor"'
Autor:
Steven A. Austin, Gary C. Visor, William O. Nelson, Robert B. Killion, Andrei Blasko, Alana Leahy-Dios, Ian J. Massey
Publikováno v:
Monatshefte fuer Chemie/Chemical Monthly. 132:789-798
The kinetic and thermodynamic solubilities of Roche (Ro) pharmaceutical compounds were determined by HPLC, titrimetry, and UV/Vis spectroscopy in aqueous buffers and in non-buffered systems. For kinetic solubility, a turbidimetric method that allows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82585a2c804f9ae39b1398b9ccb13589
https://doi.org/10.1007/s007060170065
https://doi.org/10.1007/s007060170065
Autor:
I-Lan Sue, Gary C. Visor, Jane Marshburn, Kenneth C. Cundy, Carey Nakamura, Jeng-Pyng Shaw, William A. Lee
Publikováno v:
Journal of Pharmaceutical Sciences. 86:1334-1338
The effect of formulation on oral bioavailability of the antiviral nucleotide analogue adefovir from the prodrug adefovir dipivoxil was examined in beagle dogs. A suspension formulation of adefovir dipivoxil granules was administered to five fasted m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d089698898a63ef53a330ba08b50b3c
https://doi.org/10.1021/js970264s
https://doi.org/10.1021/js970264s
Autor:
Elena Aspe, William A. Lee, Richard H. Guy, Gary C. Visor, James A. Kennedy, Richard D. Ennis
Publikováno v:
Journal of Pharmaceutical Sciences. 84:750-754
The in vitro flux (4-8 h) of cidofovir (1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine) was measured across full-thickness hairless mouse skin to evaluate potential formulations for local treatment of herpes virus infections. The effects of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c1241935a89eca1e1ee46e0bf176e3
https://doi.org/10.1002/jps.2600840617
https://doi.org/10.1002/jps.2600840617
Autor:
Kenneth C. Cundy, William A. Lee, James A. Fishback, Jeng-Pyng Shaw, Min L. Lee, Kenneth F. Soike, Gary C. Visor
Publikováno v:
Pharmaceutical Research. 11:839-843
The bioavailability of PMEA from three oral formulations of the prodrug bis(POM)-PMEA has been evaluated in fasted male cynomolgus monkeys. The formulations examined included a hydroxy-propyl-β-cyclodextrin (HPBCD) complex, a PEG based cosolvent sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::584165048a669840bc27a696da6ae8bb
https://doi.org/10.1023/a:1018925723889
https://doi.org/10.1023/a:1018925723889
Autor:
Thomas Calderwood, Wen.-C. Hsu, Hi-Shi Chiang, Jane Duffy, Foster Linda Cheryl, Leo Gu, Gary C. Visor, Elizabeth A. Erdös, Kelly Peng Tsai
Publikováno v:
Pharmaceutical Research. :485-490
The thermal stability of IL-1 beta in aqueous solution as a function of temperature (5-60 degrees C), pH (2-9), buffer (acetate, citrate, tris, and phosphate), and cyroprotectants (sugars, HSA) was investigated in this study. The analytical methodolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f82085a9fa751d9872e1ed568f4bfff3
https://doi.org/10.1023/a:1015851228163
https://doi.org/10.1023/a:1015851228163
Autor:
Gary C. Visor, Richard D. Ennis, Taiyin Yang, William A. Lee, Michael Coulon, Carey Nakamura, Ray Pritchard
Publikováno v:
Pharmaceutical development and technology. 6(3)
Studies were initiated to examine the effect of formulation and process variables on the delamination process and also the influence of the glass manufacturing process, supplier, and glass surface treatment.Stress testing was performed by exposing fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d134b1eec48f68ba813702d6fa7feb
https://pubmed.ncbi.nlm.nih.gov/11485181
https://pubmed.ncbi.nlm.nih.gov/11485181
Publikováno v:
International journal of pharmaceutics. 179(2)
Degradation kinetics of cyclic HPMPC (cHPMPC), 1-[(( S )-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine, and its parent compound cidofovir (also known as HPMPC) were conducted in the pH range of 2–11 at 70°C. cHPMPC manifested greate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b05aff5e9250eb18e000f1da0fd70a8
https://pubmed.ncbi.nlm.nih.gov/10053218
https://pubmed.ncbi.nlm.nih.gov/10053218
Publikováno v:
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 53(16)
The stability of cidofovir in i.v. admixtures under refrigerator and room temperature conditions was studied. Admixtures of cidofovir 0.21 and 8.12 mg/mL in 0.9% sodium chloride injection or 5% dextrose injection and of 0.085 and 3.51 mg/mL in 5% dex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ddd83a7685eb78dd15155d9457c90e
https://pubmed.ncbi.nlm.nih.gov/8862207
https://pubmed.ncbi.nlm.nih.gov/8862207
Publikováno v:
ACS Symposium Series ISBN: 9780841226241
Polymeric Delivery Systems: Properties and Applications
Polymeric Delivery Systems: Properties and Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b4e645d247c93ac6afb8a4de13cd76
https://doi.org/10.1021/bk-1993-0520.ch010
https://doi.org/10.1021/bk-1993-0520.ch010
Publikováno v:
Journal of AOAC INTERNATIONAL. 69:20-24
A reverse phase liquid chromatographic (LC) procedure is described for quantitating oxfendazole (2-(methoxycarbonylamino)-5-phenyIsuIfinylbenzimidazole)) in swine premix. Sample preparation consists of extracting oxfendazole with an acetone-methanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f10fc4b66c84a77517af10167c9eca2
https://doi.org/10.1093/jaoac/69.1.20
https://doi.org/10.1093/jaoac/69.1.20