Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gary C. Port"'
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT SpxA is a unique transcriptional regulator highly conserved among members of the phylum Firmicutes that binds RNA polymerase and can act as an antiactivator. Why some Firmicutes members have two highly similar SpxA paralogs is not understood
Externí odkaz:
https://doaj.org/article/7d9324830c88471984a4b367b730af2a
Publikováno v:
mBio, Vol 4, Iss 5 (2013)
ABSTRACT The ExPortal of Streptococcus pyogenes is a focal microdomain of the cytoplasmic membrane that clusters the translocons of the general secretory pathway with accessory factors to facilitate the maturation of secreted polypeptides. While it i
Externí odkaz:
https://doaj.org/article/cd66a7f053464023bb474c0c740cef21
Autor:
Hailyn V. Nielsen, Pascale S. Guiton, Kimberly A. Kline, Gary C. Port, Jerome S. Pinkner, Fabrice Neiers, Staffan Normark, Birgitta Henriques-Normark, Michael G. Caparon, Scott J. Hultgren
Publikováno v:
mBio, Vol 3, Iss 4 (2012)
ABSTRACT Though the bacterial opportunist Enterococcus faecalis causes a myriad of hospital-acquired infections (HAIs), including catheter-associated urinary tract infections (CAUTIs), little is known about the virulence mechanisms that it employs. H
Externí odkaz:
https://doaj.org/article/1dd6e6ab18ed4031aab6ae0a3e40e812
Publikováno v:
Infect Immun
The second messenger cyclic di-AMP (c-di-AMP) controls biofilm formation, stress response, and virulence in Streptococcus pyogenes. The deletion of the c-di-AMP synthase gene, dacA, results in pleiotropic effects including reduced expression of the s
Publikováno v:
Journal of Bacteriology. 201
Streptococcus agalactiae, a leading cause of sepsis and meningitis in neonates, utilizes multiple virulence factors to survive and thrive within the human host during an infection. Unique among the pathogenic streptococci, S. agalactiae uses a bifunc
Publikováno v:
Genes
Genes, Vol 8, Iss 8, p 197 (2017)
Genes, Vol 8, Iss 8, p 197 (2017)
Signal transduction pathways enable organisms to monitor their external environment and adjust gene regulation to appropriately modify their cellular processes. Second messenger nucleotides including cyclic adenosine monophosphate (c-AMP), cyclic gua
Publikováno v:
Molecular Microbiology. 74:956-973
The bacterial pathogen Listeria monocytogenes survives under a myriad of conditions in the outside environment and within the human host where infections can result in severe disease. Bacterial life within the host requires the expression of genes wi
Autor:
Gary C. Port, Nancy E. Freitag
Publikováno v:
Infection and Immunity. 75:5886-5897
Upon bacterial entry into the cytosol of infected mammalian host cells, the central virulence regulator PrfA ofListeria monocytogenesbecomes activated and induces the expression of numerous factors which contribute to bacterial pathogenesis. The mech
Publikováno v:
Genome Announcements
We report the complete genome assemblies of the group A Streptococcus pyogenes serotype emm 6 strain D471 and its streptomycin-resistant derivative JRS4. Both of these well-studied laboratory strains have been extensively characterized over the past