Výsledky vyhledávání - "Gary Bradshaw"

HUWE1 Amplifies Ubiquitin Modifications to Broadly Stimulate Clearance of Proteins and Aggregates

Autor: Mengying Zhou, Rui Fang, Louis Colson, Katherine Donovan, Moritz Hunkeler, Siyi Chen, Yuyu Song, Can Zhang, Dong-hoon Lee, Gary Bradshaw, Robyn Eisert, Yihong Ye, Marian Kalocsay, Alfred Goldberg, Eric S Fischer, Ying Lu

Publikováno v: bioRxiv

Selective breakdown of proteins and aggregates is crucial for maintaining normal cellular activities and is involved in the pathogenesis of diverse diseases. How the cell recognizes and tags these targets in different structural states for degradatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1dba68e169e00542e70ec131c16553
https://europepmc.org/articles/PMC10312588/

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Atheroprotective Potential of Macrophage-Derived Phospholipid Transfer Protein in Low-Density Lipoprotein Receptor-Deficient Mice Is Overcome by Apolipoprotein AI Overexpression

Autor: David T. Valenta, Linda K. Curtiss, David J. Bonnet, Audrey S. Black, Catherine Desrumaux, Nicolas Ogier, Gary Bradshaw, Laurent Lagrost

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 26:1572-1578

Objective— Using bone marrow transplantation, we assessed the impact of macrophage-derived phospholipid transfer protein (PLTP) on lesion development in hypercholesterolemic mice that expressed either normal levels of mouse apolipoprotein AI (apoAI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c596892044e3ca3f62c855417fb7740
https://doi.org/10.1161/01.atv.0000225700.43836.ae

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Participation of macrophages in atherosclerotic lesion morphology in LDLr−/− mice

Autor: Natalie K. Schiller, Audrey S. Black, Gary Bradshaw, Linda K. Curtiss, David J. Bonnet

Publikováno v: Journal of Lipid Research, Vol 45, Iss 8, Pp 1398-1409 (2004)

Lystbeige (beige) mice crossed with LDL receptor-deficient (LDLr-/-) mice had a distinct atherosclerotic lesion morphology that was not observed in LDLr-/- mice. This morphology is often associated with a stable plaque phenotype. We hypothesized that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33eebfd5d531a4e1d68405c790e5dca
http://www.sciencedirect.com/science/article/pii/S0022227520313018

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Facilitated replacement of Kupffer cells expressing a paraoxonase-1 transgene is essential for ameliorating atherosclerosis in mice

Autor: Christopher K. Glass, Gary Bradshaw, Linda K. Curtiss, Kimberly R. Davis, Andrew C. Li, Roger A. Davis, Jon H. Miyake, Alejandra Gutierrez

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 102(31)

Resident macrophages (i.e., Kupffer cells) are derived from hematopoietic stem cells (HSCs) and are primarily responsible for the removal from plasma of oxidized forms of low-density lipoprotein (LDL). The therapeutic potential of Kupffer cell expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621d2a367195ac1e73cea8f9c725f00e
https://pubmed.ncbi.nlm.nih.gov/16043712

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Dynamic Measures of Spatial Ability, Executive Function, and Social Intelligence

Autor: J. M. Giesen, Gary Bradshaw

By improving selection and classification of incoming military personnel, the Navy has an opportunity to recruit and retain talented sailors, thereby increasing readiness and reducing personnel costs. Here we introduce six new measures that are usefu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::369260068c14418bac5e8f47dd313ad3
https://doi.org/10.21236/ada414704

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