Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Gary B. Huffnagle"'
Autor:
Llilian Arzola-Martínez, Keerthikka Ravi, Gary B. Huffnagle, Nicholas W. Lukacs, Wendy Fonseca
Publikováno v:
Frontiers in Microbiomes, Vol 2 (2024)
Lactobacillus johnsonii is a commensal bacterium that has been isolated from vaginal and gastrointestinal (GI) tracts of vertebrate hosts, including humans, rodents, swine, and poultry. Lactobacillus-based probiotic supplements are popular because of
Externí odkaz:
https://doaj.org/article/68d0988312b34c33ba103725bee7fade
Publikováno v:
Viruses, Vol 16, Iss 2, p 220 (2024)
Background: Respiratory syncytial virus (RSV) infection is a major cause of lower respiratory tract infection, especially in infants, and increases the risk of recurrent wheezing and asthma. Recently, researchers have proposed a possible association
Externí odkaz:
https://doaj.org/article/ff5354db5fbf4a85b012abf90fdb7dc7
Autor:
Nobuhiro Asai, Alexander D. Ethridge, Wendy Fonseca, Kazuma Yagi, Andrew J. Rasky, Susan B. Morris, Nicole R. Falkowski, Yvonne J. Huang, Gary B. Huffnagle, Nicholas W. Lukacs
Publikováno v:
Physiological Reports, Vol 11, Iss 13, Pp n/a-n/a (2023)
Abstract The pathogenesis of asthma has been partially linked to lung and gut microbiome. We utilized a steroid‐resistant chronic model of cockroach antigen‐induced (CRA) asthma with corticosteroid (fluticasone) treatment to examine lung and gut
Externí odkaz:
https://doaj.org/article/30e8a75ff6d64684a97b715c7d4cd382
Autor:
Jennifer M. Baker, Kevin J. Hinkle, Roderick A. McDonald, Christopher A. Brown, Nicole R. Falkowski, Gary B. Huffnagle, Robert P. Dickson
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Background Low-biomass microbiome studies (such as those of the lungs, placenta, and skin) are vulnerable to contamination and sequencing stochasticity, which obscure legitimate microbial signal. While human lung microbiome studies have rigo
Externí odkaz:
https://doaj.org/article/fa66e20a7c3643bea5694f1810dcf9c5
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Several environmental factors can influence the development and establishment of the early-life microbiota. For example, exposure to different environmental factors from birth to childhood will shape the lung and gut microbiota and the development of
Externí odkaz:
https://doaj.org/article/24346f15367f4eb1954ecf430242a170
Autor:
Kristopher Opron, Lesa A. Begley, John R. Erb-Downward, Christine Freeman, Siddharth Madapoosi, Neil E. Alexis, Igor Barjaktarevic, R. Graham Barr, Eugene R. Bleecker, Russell P. Bowler, Stephanie A. Christenson, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Claire M. Doerschuk, Mark T. Dransfield, MeiLan K. Han, Nadia N. Hansel, Annette T. Hastie, Eric A. Hoffman, Robert J. Kaner, Jerry Krishnan, Wanda K. O’Neal, Victor E. Ortega, Robert Paine, Stephen P. Peters, J. Michael Wells, Prescott G. Woodruff, Fernando J. Martinez, Jeffrey L. Curtis, Gary B. Huffnagle, Yvonne J. Huang
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) is heterogeneous in development, progression, and phenotypes. Little is known about the lung microbiome, sampled by bronchoscopy, in milder COPD and its relationships to clinical features that ref
Externí odkaz:
https://doaj.org/article/10a254afe79640d29b0d02561b498bb0
Autor:
Kelsey G. Stark, Nicole R. Falkowski, Christopher A. Brown, Roderick A. McDonald, Gary B. Huffnagle
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
There is heterogeneity inherent in the immune responses of individual mice in murine models of food allergy, including anaphylaxis, similar to the clinical heterogeneity observed in humans with food allergies to a defined food. One major driver of th
Externí odkaz:
https://doaj.org/article/97e6975939734ef18a8ce8059ababf91
Autor:
Keerthikka Ravi, Nicole R. Falkowski, Brittan S. Scales, Volha D. Akulava, Leonid N. Valentovich, Gary B. Huffnagle
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The type III secretion system (T3SS) is a needle-like structure found in Gram-negative pathogens that directly delivers virulence factors like toxins and effector molecules into eukaryotic cells. The T3SS is classified into different familie
Externí odkaz:
https://doaj.org/article/2446573e4eda4225a3499b7275b5f58c
Autor:
Taeko K. Noah, Jee-Boong Lee, Christopher A. Brown, Amnah Yamani, Sunil Tomar, Varsha Ganesan, Rodney D. Newberry, Gary B. Huffnagle, Senad Divanovic, Simon P. Hogan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Food allergy is an emerging epidemic, and the underlying mechanisms are not well defined partly due to the lack of robust adjuvant free experimental models of dietary antigen sensitization. As housing mice at thermoneutrality (Tn) - the temperature o
Externí odkaz:
https://doaj.org/article/b6eaf79e8fe746ee896714493af590e0
Autor:
John R. Erb-Downward, Nicole R. Falkowski, Jennifer C. D’Souza, Lisa M. McCloskey, Roderick A. McDonald, Christopher A. Brown, Kerby Shedden, Robert P. Dickson, Christine M. Freeman, Kathleen A. Stringer, Betsy Foxman, Gary B. Huffnagle, Jeffrey L. Curtis, Sara D. Adar
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT The bacterial microbiome of human body sites, previously considered sterile, remains highly controversial because it can be challenging to isolate signal from noise when low-biomass samples are being analyzed. We tested the hypothesis that s
Externí odkaz:
https://doaj.org/article/ad2262303bef4b7eacca97265e84955c