Predictors of the placebo analgesia response in randomized controlled trials of chronic pain

Autor: Scott Marshall, Märta Segerdahl, Donald D. Price, Nanna B. Finnerup, Bernd Lange, Lene Vase, Charlie Liss, Jan Vollert, Troels S. Jensen, Gary Atkinson, Xiaopeng Miao, Robert Nemeth, Christoph Maier

Publikováno v: Vase, L, Vollert, J, Finnerup, N B, Miao, X, Atkinson, G, Marshall, S, Nemeth, R, Lange, B, Liss, C, Price, D D, Maier, C, Jensen, T S & Segerdahl, M 2015, ' Predictors of the placebo analgesia response in randomized controlled trials of chronic pain: a meta-analysis of the individual data from nine industrially sponsored trials ', Pain, vol. 156, no. 9, pp. 1795-802 . https://doi.org/10.1097/j.pain.0000000000000217

A large number of analgesics have failed to prove superiority over placebo in randomized controlled trials (RCTs), and as this has been related to increasing placebo responses, there is currently an interest in specifying predictors of the placebo re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936d6eb4a08bd9302c34a730abd85cb9
https://doi.org/10.1097/j.pain.0000000000000217

Screening for Cancer-Related Neuropathic Pain in the Oncology Outpatient Setting in the United Kingdom

Autor: Chantal van Litsenburg, Susan Davidson, Gary Atkinson, Alison Birtle

Publikováno v: The Open Pain Journal. 6:208-216

This article reports the outcomes of a sub-analysis of United Kingdom (UK) data collected during a noninterventional, cross-sectional study conducted in five European countries. The primary aim was to estimate the prevalence of cancer-related neuropa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2808197905de30c0b08c00c65e848e8d
https://doi.org/10.2174/1876386301306010208

Multiplicity: discussion points from the Statisticians in the Pharmaceutical Industry multiplicity expert group

Autor: Gary Atkinson, James H. Roger, Eddie Channon, Chrissie Fletcher, Jeff Maca, Abdel Douiri, Alan Phillips, Thomas Jaki, Paul Terrill, David Morgan

Publikováno v: Pharmaceutical Statistics. 12:255-259

In May 2012, the Committee of Health and Medicinal Products issued a concept paper on the need to review the points to consider document on multiplicity issues in clinical trials. In preparation for the release of the updated guidance document, Stati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f068db61ca37cfa9b1abbe0abd289169
https://doi.org/10.1002/pst.1584

Wireless Sensors for Space Applications

Autor: William WILSON, Gary ATKINSON

Publikováno v: Sensors & Transducers, Vol 13, Iss Special Issue, Pp 1-9 (2011)

From ground tests to operations on orbit and on the Moon, many space applications could benefit from small, passive, wireless sensors. Eliminating wires in spacecraft could reduce launch costs through the reduction of mass and lead to reduced fabrica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::4a9d06d4906aa9f25235f79be38cd2bf
http://www.sensorsportal.com/HTML/DIGEST/december_2011/P_SI_162.pdf

The role of the minimum clinically important difference and its impact on designing a trial

Autor: Gary Atkinson, Christy Chuang-Stein, Ian Hirsch, Simon Kirby

Publikováno v: Pharmaceutical Statistics. 10:250-256

The minimum clinically important difference (MCID) between treatments is recognized as a key concept in the design and interpretation of results from a clinical trial. Yet even assuming such a difference can be derived, it is not necessarily clear ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2a56894cabec0eb164dd307137dd30
https://doi.org/10.1002/pst.459