Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Gary A. Oltmans"'
Autor:
Gary A. Oltmans, Susan M. Drengler
Publikováno v:
Brain Research. 615:175-179
Loss of the inferior olive-climbing fiber input to the cerebellar cortex doubles the simple spike activity of the cerebellar Purkinje cell. There is a 3- to 4-fold increase in Purkinje cell messenger RNA for the 67 kDa form of glutamic acid decarboxy
Publikováno v:
The Journal of Neuroscience. 10:1874-1885
In the rat mutant dystonic (dt), glutamic acid decarboxylase (GAD) activity in the deep cerebellar nuclei (DCN) is elevated compared to normal littermates. The distribution of this increase within the DCN, and the effect upon GABA receptor density, w
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 16(5)
Loss of the inferior olive-climbing fiber input to the cerebellar cortex after treatment with the neurotoxin 3-acetylpyridine (3-AP) has been reported to double the simple spike activity of the cerebellar Purkinje cell and eliminates complex spike ac
Publikováno v:
Brain research bulletin. 29(3-4)
Immunocytochemistry was used to examine the distribution, size, and density of glutamic acid decarboxylase immunoreactive (GAD+) puncta in two animal models with movement disorders, the genetically dystonic (dt) rat and rats with 3-acetylpyridine (3A
Publikováno v:
Brain Research. 222:411-416
Despite significantly elevated hypothalamic norepinephrine levels, genetically obese mice ( ob/ob ) had more hypothalamic α-adrenergic receptors than their lean littermates. This receptor increase appeared to be specific to the α-receptors in the h
Publikováno v:
Hypertension. 7:333-339
Increased sympathetic outflow from the central nervous system to the periphery may contribute to the initiation of hypertension in spontaneously hypertensive rats (SHR). As this alteration in sympathetic activity may be mediated in part by alpha-adre
Publikováno v:
Brain Research. 96:390-394
Publikováno v:
Brain Research. 366:89-97
The genetically dystonic rat (dt) has elevated resting levels of cerebellar norepinephrine (NE) in comparison with phenotypically normal littermates. This difference is not secondary to cerebellar hypoplasia. Increased NE is observed as early as post
Publikováno v:
Neuropharmacology. 27:849-855
Administration of the beta-carboline alkaloid, harmaline, causes the neurons of the inferior olive to fire synchronously and to act as a pacemaker for the generation of tremor. Rats treated daily with harmaline showed a progressive loss of drug-induc
Publikováno v:
Journal of Comparative and Physiological Psychology. 90:144-155
The ventral noradrenergic bundle (VB) of the rate brain has been proposed as the substrate for the hyperphagia and obesity produced by ventromedial hypothalamic lesions. To determine the relationship between body weight and damage to the VB, the effe