Zobrazeno 1 - 10 of 119 pro vyhledávání: '"Gary, Kanel"'
1
Akademický článek
Niacin‐Induced Anicteric Microvesicular Steatotic Acute Liver Failure
Autor: Kenneth Leung, Michael Quezada, Zhengshan Chen, Gary Kanel, Neil Kaplowitz
Publikováno v: Hepatology Communications, Vol 2, Iss 11, Pp 1293-1298 (2018)
Niacin (vitamin B3) is available as a prescription medication and over‐the‐counter supplement. Although it is well known for its vasodilatory effect, it has also been associated with mild hepatotoxicity and, rarely, acute liver failure. We presen
Externí odkaz: https://doaj.org/article/f75d8c5f28d6476da42ed61756f8dfaf
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2
Akademický článek
Targeted Deletion of ER Chaperone GRP94 in the Liver Results in Injury, Repopulation of GRP94-Positive Hepatocytes, and Spontaneous Hepatocellular Carcinoma Development in Aged Mice
Autor: Wan-Ting Chen, Dat Ha, Gary Kanel, Amy S. Lee
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 8, Pp 617-626 (2014)
Hepatocellular carcinoma (HCC) often results from chronic liver injury and severe fibrosis or cirrhosis, but the underlying molecular pathogenesis is unclear. We previously reported that deletion of glucose regulated protein 94 (GRP94), a major endop
Externí odkaz: https://doaj.org/article/86122ee5d95141818acb090b3ef87574
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4
Hepatic mitochondrial SAB deletion or knockdown alleviates diet induced metabolic syndrome, steatohepatitis and hepatic fibrosis
Autor: Sanda Win, Neil Kaplowitz, Brad Wanken, Ying Wang, Robert W.M. Min, Meng Li, Gary Kanel, Filbert W.M. Aung, Ayako Suzuki, Yibu Chen, Tin Aung Than, Susan F. Murray, Mariam Aghajan, Jun Zhang
Publikováno v: Hepatology
BACKGROUND AND AIMS The hepatic mitogen-activated protein kinase (MAPK) cascade leading to c-Jun N-terminal kinase (JNK) activation has been implicated in the pathogenesis of nonalcoholic fatty liver (NAFL)/NASH. In acute hepatotoxicity, we previousl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83508583500ef97455ec6feb4fe5aab6
https://europepmc.org/articles/PMC8639630/
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5
IgG:IgM Ratios of Liver Plasma Cells Reveal Similar Phenotypes of Primary Biliary Cholangitis With and Without Features of Autoimmune Hepatitis
Autor: Jeffrey Kahn, Brian T. Lee, Yun Wang, Hyosun Han, Gary Kanel, Liyun Yuan, Neil Kaplowitz, Lily Dara, Alexander H Yang, John A. Donovan
Publikováno v: Clin Gastroenterol Hepatol
Within the spectrum of autoimmune liver diseases, there are patients who manifest features of more than one disease, which was previously identified as having overlap syndrome1,2 and is now referred to as variant syndromes. The most common variant sy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941b49b45db7b338e09357c933add594
https://doi.org/10.1016/j.cgh.2019.11.024
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6
Prediction of histologic alcoholic hepatitis based on clinical presentation limits the need for liver biopsy
Autor: Behnam Saberi, Nitzan Roth, Anthony S. Buzzanco, Neil Kaplowitz, Jared Macklin, Sugantha Govindarajan, Gary Kanel, John A. Donovan, Samuel W. French, Andrew Stolz
Publikováno v: Hepatology Communications
The clinical presentation of alcoholic hepatitis (AH) can be mimicked by other alcoholic liver diseases. The aim of this study was to identify clinical features that predict AH on liver biopsy. Biopsies from patients hospitalized for presumed severe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944943cf6ca62307afd4f1626af168dd
https://doi.org/10.1002/hep4.1119
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7
Hepatic angiosarcoma with clinical and histological features of Kasabach-Merritt syndrome
Autor: Tae Hun Kim, Leah Lin, Sanya Wadhwa, Gary Kanel, Takeshi Saito
Publikováno v: World Journal of Gastroenterology
Hepatic angiosarcoma is a mesenchymal tumor originating from liver sinusoidal endothelial cells. It is an extremely rare malignant neoplasm accounting for less than 1% of primary malignant liver tumors. The deregulated coagulopathy that can be seen i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b33229c65d5d68b1edd3d0b46264bf
http://europepmc.org/articles/PMC5385411
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