Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Gary, Chicchi"'
Autor:
Andrew J, Kassick, Jinlong, Jiang, Jaime, Bunda, David, Wilson, Jianming, Bao, Huagang, Lu, Peter, Lin, Richard G, Ball, George A, Doss, Xinchun, Tong, Kwei-Lan C, Tsao, Hong, Wang, Gary, Chicchi, Bindhu, Karanam, Richard, Tschirret-Guth, Koppara, Samuel, Donald F, Hora, Sanjeev, Kumar, Maria, Madeira, Waisi, Eng, Richard, Hargreaves, Mona, Purcell, Liza, Gantert, Jacquelyn, Cook, Robert J, DeVita, Sander G, Mills
Publikováno v:
Journal of medicinal chemistry. 56(14)
Hydroisoindoline 2 has been previously identified as a potent, brain-penetrant NK1 receptor antagonist with a long duration of action and improved profile of CYP3A4 inhibition and induction compared to aprepitant. However, compound 2 is predicted, ba
Autor:
Dennis J. Underwood, Ralph Hirschmann, Edward R. Thornton, Rachel D. van Rijn, Gary Chicchi, Elizabeth T. Birzin, Amos B. Smith, Susan P. Rohrer, Cheryl T. Mcvaugh, Vidya K. Prasad
Publikováno v:
Journal of medicinal chemistry. 46(10)
In our continuing program exploring glucose-based peptidomimetics of somatostatin (SRIF-14), we sought to improve the water solubility of our glycosides. This led to insights into the nature of the ligand binding sites at the SRIF receptor. Replaceme