Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Garth Powis"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115024- (2023)
The pleckstrin homology [PH] domain is a structural fold found in more than 250 proteins making it the 11th most common domain in the human proteome. 25% of family members have more than one PH domain and some PH domains are split by one, or several
Externí odkaz:
https://doaj.org/article/7afab2546f8f43c7ba4c671b79b61540
Autor:
Petrus R. de Jong, Koji Taniguchi, Alexandra R. Harris, Samuel Bertin, Naoki Takahashi, Jen Duong, Alejandro D. Campos, Garth Powis, Maripat Corr, Michael Karin, Eyal Raz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
It is unclear how the extracellular signal-regulated kinases 1 and 2 (ERK1/2) pathways interact with other signals in intestinal epithelial cells. Here, the authors show that upon loss of Erk1/2, or pharmacological inhibition of MEK1/2, the ERK5 path
Externí odkaz:
https://doaj.org/article/1be108f4d4194c2ab206271625dab19f
Autor:
Bénédicte F. Jordan, Matthew Runquist, Natarajan Raghunand, Amanda Baker, Ryan Williams, Lynn Kirkpatrick, Garth Powis, Robert J. Gillies
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 5, Pp 475-485 (2005)
PX-478 is a new agent known to inhibit the hypoxiaresponsive transcription factor, HIF-1α, in experimental tumors. The current study was undertaken in preparation for clinical trials to determine which noninvasive imaging endpoint(s) is sensitive to
Externí odkaz:
https://doaj.org/article/ce2dc6f636d54797bd4d11db1eac85ae
Autor:
Yanan Yang, Kentaro Iwanaga, Maria Gabriela Raso, Marie Wislez, Amy E Hanna, Eric D Wieder, Jeffrey J Molldrem, Ignacio I Wistuba, Garth Powis, Francesco J Demayo, Carla F Kim, Jonathan M Kurie
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2220 (2008)
Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related death in Western countries. Developing more effective NSCLC therapeutics will require the elucidation of the genetic and biochemical bases for this disease. Bronchioalveola
Externí odkaz:
https://doaj.org/article/ad338a79447140c2bcaefdfcc4ee8781
Autor:
Garth Powis, Hyun Cheol Chung, Seung Woo Park, Kyu Hyun Park, Xianglan Zhang, You Keun Shin, Tae Soo Kim, Eun Jeong Yu, Sun Young Rha, Hei-Cheul Jeung, Jeong Min Kim
Supplementary Figure 5: The specificity of RAV-18 to ADAM-9 protease activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78187b16c2f0a22283dfceb1ad231bf8
https://doi.org/10.1158/1535-7163.22502650.v1
https://doi.org/10.1158/1535-7163.22502650.v1
Autor:
Garth Powis, Hyun Cheol Chung, Seung Woo Park, Kyu Hyun Park, Xianglan Zhang, You Keun Shin, Tae Soo Kim, Eun Jeong Yu, Sun Young Rha, Hei-Cheul Jeung, Jeong Min Kim
Supplementary Figure 4: In vivo treatment of RAV-18.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e28b321a57add563d75fb02a01ed4a
https://doi.org/10.1158/1535-7163.22502665
https://doi.org/10.1158/1535-7163.22502665
Autor:
Garth Powis, Hyun Cheol Chung, Seung Woo Park, Kyu Hyun Park, Xianglan Zhang, You Keun Shin, Tae Soo Kim, Eun Jeong Yu, Sun Young Rha, Hei-Cheul Jeung, Jeong Min Kim
Advanced gastric cancer is one of the most aggressive gastrointestinal malignancies, and ADAM (A disintegrin and metalloproteinase)-9 is a cell-surface membrane glycoprotein with oncogenic properties that is overexpressed in several cancers. Herein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f671bec8251cd7b9d829ff93ec38fa
https://doi.org/10.1158/1535-7163.c.6537142
https://doi.org/10.1158/1535-7163.c.6537142
Autor:
Scott Kopetz, Garth Powis, Michael J. Overman, Jeffrey Morris, Bradley M. Broom, Mingshan Cheng, Susan Airhart, Feng Tian, Christopher Bristow, Bahar Salimian Rizi, Alexey V. Sorokin, Ji Wu, Shanequa Manuel, Maria P. Morelli, Andreas Varkaris, David G. Menter, Zhi-Qin Jiang, Kanwal Raghav, Anastasia Katsiampoura
Association between surgical specimen size and rate of PDX establishment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1a3561b3894370a65e992a0deea967
https://doi.org/10.1158/1535-7163.22503978.v1
https://doi.org/10.1158/1535-7163.22503978.v1
Autor:
Garth Powis, Hyun Cheol Chung, Seung Woo Park, Kyu Hyun Park, Xianglan Zhang, You Keun Shin, Tae Soo Kim, Eun Jeong Yu, Sun Young Rha, Hei-Cheul Jeung, Jeong Min Kim
Supplementary Figure 1: Transcription level of ADAM9 in gastric cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139e6bd2548d3e4315c1603e60b8a917
https://doi.org/10.1158/1535-7163.22502674
https://doi.org/10.1158/1535-7163.22502674
Autor:
Garth Powis, Hyun Cheol Chung, Seung Woo Park, Kyu Hyun Park, Xianglan Zhang, You Keun Shin, Tae Soo Kim, Eun Jeong Yu, Sun Young Rha, Hei-Cheul Jeung, Jeong Min Kim
Supplementary Figure 2: Efficiency of siRNA transfection against ADAM-9, -10 and -17 in 3 gastric cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cb27244f4f8aa7009d1c8e60e8eaae
https://doi.org/10.1158/1535-7163.22502671.v1
https://doi.org/10.1158/1535-7163.22502671.v1