Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Garth M. Bray"'
Autor:
Deanna L. Huggett, Garth M. Bray
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 43:5-14
The National Population Health Study of Neurological Conditions, a partnership between Neurological Health Charities Canada and the Government of Canada, was the largest study of neurological diseases, disorders, and injuries ever conducted in Canada
Publikováno v:
Annals of the New York Academy of Sciences. 883:427-438
Publikováno v:
Proceedings of the National Academy of Sciences. 95:3978-3983
In this study, we demonstrate that: ( i ) injection of an adenovirus (Ad) vector containing the brain-derived neurotrophic factor (BDNF) gene (Ad.BDNF) into the vitreous chamber of adult rats results in selective transgene expression by Müller cells
Publikováno v:
Journal of Neurocytology. 27:187-196
Regenerated retinal ganglion cell (RGC) axons can re-form functional synapses with target neurons in the superior colliculus (SC). Because preterminal axon branching determines the size, shape and density of innervation fields, we investigated the br
Publikováno v:
The Journal of Neuroscience. 16:5344-5350
Distal to a peripheral nerve transection, myelin degradation and Schwann cell (SC) proliferation are accompanied by a marked upregulation of brain-derived neurotrophic factor (BDNF) and a decrease of ciliary neurotrophic factor (CNTF) in non-neuronal
Publikováno v:
The Journal of Neuroscience. 16:3887-3894
To investigate the influences of growth factors on axonal regeneration in the mammalian CNS, we used intracellular tracers to quantitate the effects of brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-4/5, or NT-3 on individual retinal gan
Publikováno v:
Biochemistry and Cell Biology. 73:599-604
After injury in the central nervous system of adult mammals, many of the axons that remain attached to their intact cell bodies degenerate and decrease in calibre. To understand this process better, we have investigated the relationship between axona
Publikováno v:
Proceedings of the National Academy of Sciences. 91:1632-1636
Optic nerve transection in adult rats results in the death of approximately 50% of the axotomized retinal ganglion cells (RGCs) by 1 week and nearly 90% by 2 weeks after injury. The capacity of brain-derived neurotrophic factor (BDNF) to prevent this
Publikováno v:
The Journal of Neuroscience. 14:590-598
The capacity of regenerating axons for long-term growth and synaptic plasticity was investigated in the visual system of adult hamsters. Four to six and 8–10 months after the eye and the superior colliculus (SC) were linked by a peripheral nerve (P