Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Garth L, Abrahams"'
Autor:
Matthew W Barwick, Sidne Fanucci, Siso Mbanxa, Khanyisile Buthelezi, Michael D Jukes, Garth L Abrahams, Earl Prinsloo
Access to desktop additive manufacturing is growing and the argument could be made for 3D printers to be standard laboratory equipment. The power of the printers lies in the democratisation of scientific equipment. Traditional agarose gel electrophor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bf5c8b093948327bf3eb0f726f6e4c4
https://doi.org/10.1101/2023.03.22.533785
https://doi.org/10.1101/2023.03.22.533785
Autor:
Melissa D. Chengalroyen, Mandy K. Mason, Alessandro Borsellini, Raffaella Tassoni, Garth L. Abrahams, Sasha Lynch, Yong-Mo Ahn, Jon Ambler, Katherine Young, Brendan M. Crowley, David B. Olsen, Digby F. Warner, Clifton E. Barry III, Helena I. M. Boshoff, Meindert H. Lamers, Valerie Mizrahi
Publikováno v:
ACS Infectious Diseases, 8(3), 612-625. AMER CHEMICAL SOC
Natural products provide a rich source of potential antimicrobials for treating infectious diseases for which drug resistance has emerged. Foremost among these diseases is tuberculosis. Assessment of the antimycobacterial activity of nargenicin, a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fb2ed0c508f40ee8c1ebeb5a93f63a
https://hdl.handle.net/1887/3514350
https://hdl.handle.net/1887/3514350
Autor:
Melissa D, Chengalroyen, Mandy K, Mason, Alessandro, Borsellini, Raffaella, Tassoni, Garth L, Abrahams, Sasha, Lynch, Yong-Mo, Ahn, Jon, Ambler, Katherine, Young, Brendan M, Crowley, David B, Olsen, Digby F, Warner, Clifton E, Barry Iii, Helena I M, Boshoff, Meindert H, Lamers, Valerie, Mizrahi
Publikováno v:
ACS infectious diseases. 8(3)
Natural products provide a rich source of potential antimicrobials for treating infectious diseases for which drug resistance has emerged. Foremost among these diseases is tuberculosis. Assessment of the antimycobacterial activity of nargenicin, a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b64455ca74c05abd995614158f98e672
https://pubmed.ncbi.nlm.nih.gov/35143160
https://pubmed.ncbi.nlm.nih.gov/35143160
Autor:
Digby F. Warner, Melissa D. Chengalroyen, Sasha L. Lynch, Katherine Young, Mandy K. Mason, Brendan M. Crowley, Raffaella Tassoni, Valerie Mizrahi, David B. Olsen, Clifton E. Barry, Alessandro Borsellini, Garth L. Abrahams, Yong-Mo Ahn, Jon Ambler, Helena I. Boshoff, Meindert H Lamers
SUMMARYNatural products provide a rich source of potential antimicrobials for use in treating infectious diseases for which drug resistance has emerged. Foremost among these is tuberculosis. Assessment of the antimycobacterial activity of nargenicin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2413ae812a6154daa5b1ef262f9a95ec
https://doi.org/10.1101/2021.10.27.466036
https://doi.org/10.1101/2021.10.27.466036
Autor:
Bintou Ahmadou Ahidjo, Diane Kuhnert, Joanna L McKenzie, Edith E Machowski, Bhavna G Gordhan, Vickery Arcus, Garth L Abrahams, Valerie Mizrahi
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21738 (2011)
The chromosome of Mycobacterium tuberculosis (Mtb) encodes forty seven toxin-antitoxin modules belonging to the VapBC family. The role of these modules in the physiology of Mtb and the function(s) served by their expansion are unknown. We investigate
Externí odkaz:
https://doaj.org/article/095ee8d0035e4af4a73a7f473e4d4db6
Autor:
Digby F. Warner, Nackmoon Sung, Liana Tsenova, Neil G. Stoker, James C. Sacchettini, Valerie Mizrahi, Gilla Kaplan, Bavesh D. Kana, Bhavna G. Gordhan, Edith E. Machowski, Garth L. Abrahams
Publikováno v:
Journal of Bacteriology. 192:2220-2227
The environment encountered by Mycobacterium tuberculosis during infection is genotoxic. Most bacteria tolerate DNA damage by engaging specialized DNA polymerases that catalyze translesion synthesis (TLS) across sites of damage. M. tuberculosis posse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113996d57332c95f3209b6ae86d62818
https://doi.org/10.1128/jb.01135-09
https://doi.org/10.1128/jb.01135-09
Publikováno v:
Traffic. 7:950-965
Intracellular replication of Salmonella enterica requires the formation of a unique organelle termed Salmonella-containing vacuole (SCV). The type III secretion system (T3SS) encoded by Salmonella Pathogenicity Island 2 (SPI2-T3SS) has a crucial role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8989d78416fa28fb4f950d89b03419ff
https://doi.org/10.1111/j.1600-0854.2006.00454.x
https://doi.org/10.1111/j.1600-0854.2006.00454.x
Autor:
Garth L. Abrahams, Michael Hensel
Publikováno v:
Cellular Microbiology. 8:728-737
Summary Intracellular survival and replication within eukaryotic host cells is of central importance for the pathogenesis of infections caused by Salmonella enterica . Intracellular Salmonella translocates a set of effector proteins by means of a typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50d36192253a7cbbeb101c87553c652
https://doi.org/10.1111/j.1462-5822.2006.00706.x
https://doi.org/10.1111/j.1462-5822.2006.00706.x
Publikováno v:
Traffic. 7:716-730
During intracellular life, Salmonella enterica proliferate within a specialized membrane compartment, the Salmonella-containing vacuole (SCV), and interfere with the microtubule cytoskeleton and cellular transport. To characterize the interaction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8871dfe614fd6ea6cf9f0adad374e355
https://doi.org/10.1111/j.1600-0854.2006.00422.x
https://doi.org/10.1111/j.1600-0854.2006.00422.x
Publikováno v:
Anaerobe. 7:135-142
Bacteroides fragilis has two enzymes with glutamate dehydrogenase (GDH) activity, namely, a dual cofactor NAD(P)H-dependent GDHA, and an NADH-specific GDHB. The presence of two enzymes with the same function is unusual and may play a role in the abil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f2222caa3d930115cba75457db01e9
https://doi.org/10.1006/anae.2001.0381
https://doi.org/10.1006/anae.2001.0381