Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Garry Lund"'
Autor:
Yutaka Takebe, Carrie J Saucedo, Garry Lund, Rie Uenishi, Saiki Hase, Takayo Tsuchiura, Norman Kneteman, Koreen Ramessar, D Lorne J Tyrrell, Masayuki Shirakura, Takaji Wakita, James B McMahon, Barry R O'Keefe
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64449 (2013)
Hepatitis C virus (HCV) infection is a significant public health problem with over 170,000,000 chronic carriers and infection rates increasing worldwide. Chronic HCV infection is one of the leading causes of hepatocellular carcinoma which was estimat
Externí odkaz:
https://doaj.org/article/c8a6cc18c5d049bf83106bd356cfc590
Autor:
Jamie T. Lewis, William R. Addison, Anwar Anwar-Mohamed, Donna N. Douglas, Christopher Hao Pu, Rakesh Bhat, Garry Lund, Michael Logan, Norman M. Kneteman, Richard Lehner
Publikováno v:
Journal of Biological Chemistry. 291:1974-1990
Cytopathic effects are currently believed to contribute to hepatitis C virus (HCV)-induced liver injury and are readily observed in Huh7.5 cells infected with the JFH-1 HCV strain, manifesting as apoptosis highly correlated with growth arrest. Reacti
Autor:
Garry Lund, Catherine Fauvelle, Sneha Rangarajan, Steven K. H. Foung, Frederick W. Holtsberg, Thomas F. Baumert, Zhen Yong Keck, Norman M. Kneteman, Patrick Lau, Thomas R. Fuerst, Justin R. Bailey, Brian G. Pierce, M. Javad Aman, Kelly L. Warfield, Roy A. Mariuzza, Yong Wang, Grant C. Liao
Publikováno v:
Hepatology
Hepatology, Wiley-Blackwell, 2016, 64 (6), ⟨10.1002/hep.28850⟩
Hepatology, Wiley-Blackwell, 2016, 64 (6), ⟨10.1002/hep.28850⟩
Direct acting antivirals (DAAs) have led to a high cure rate in treated patients with chronic hepatitis C virus (HCV) infection but this still leaves a large number of treatment failures secondary to the emergence of resistance-associated variants (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149f8554ed42a1c8085f03f0368bda92
https://hal.archives-ouvertes.fr/hal-02480063
https://hal.archives-ouvertes.fr/hal-02480063
Autor:
Sonal Asthana, Chelcey Dibben, Garry Lund, Lorne Tyrrell, Donna N. Douglas, Norman M. Kneteman, Jamie T. Lewis, Mahra Nourbakhsh
Publikováno v:
Liver Transplantation. 18:38-44
Cyclosporine A (CSA) has potent effects against hepatitis C virus (HCV) in vitro, but its clinical efficacy after liver transplantation (LT) is uncertain. We evaluated the impact of CSA and tacrolimus (TAC) with or without concomitant interferon (IFN
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 44(2)
1. Immunocompromised mice with humanized livers were developed in the mid-1990s to allow the study of human hepatotropic viruses, which normally replicate only in higher primates. The production of the uPA/SCID mouse was the vanguard of these models
Autor:
Norman M, Kneteman, Sonal, Asthana, Jamie, Lewis, Chelcey, Dibben, Donna, Douglas, Mahra, Nourbakhsh, Lorne J, Tyrrell, Garry, Lund
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 18(1)
Cyclosporine A (CSA) has potent effects against hepatitis C virus (HCV) in vitro, but its clinical efficacy after liver transplantation (LT) is uncertain. We evaluated the impact of CSA and tacrolimus (TAC) with or without concomitant interferon (IFN
Autor:
Rineke H G, Steenbergen, Michael A, Joyce, Garry, Lund, Jamie, Lewis, Ran, Chen, Nicola, Barsby, Donna, Douglas, Lin Fu, Zhu, D Lorne, Tyrrell, D Lorne J, Tyrrell, Norman M, Kneteman
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 299(4)
Although multiple determinants for hepatitis C virus (HCV) infection are known, it remains partly unclear what determines the human specificity of HCV infection. Presumably, the presence of appropriate entry receptors is essential, and this may expla
Autor:
Jamie T. Lewis, William R. Addison, David L.J. Tyrrell, Toshiyasu Kawahara, Thomas A. Churchill, Donna N. Douglas, Norman M. Kneteman, Garry Lund
Publikováno v:
Transplant international : official journal of the European Society for Organ Transplantation. 23(9)
The severe combined immunodeficiency/albumin linked-urokinase type plasminogen activator (SCID/Alb-uPA) human liver chimeric mouse model has added a new dimension to studies of liver based human diseases and has important potential for study of human
Autor:
David L.J. Tyrrell, Christian Toso, Garry Lund, Thomas A. Churchill, Jamie T. Lewis, Mahra Nourbakhsh, Donna N. Douglas, Toshiyasu Kawahara, Norman M. Kneteman
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Dise
Liver Transplantation, Vol. 16, No 8 (2010) pp. 974-982
Liver Transplantation, Vol. 16, No 8 (2010) pp. 974-982
Human hepatocyte transplantation is an alternative treatment for acute liver failure and liver diseases involving enzyme deficiencies. Although it has been successfully applied in selected recipients, both isolation and transplantation outcomes have
Autor:
Foster, John R.1 (AUTHOR), Lund, Garry2 (AUTHOR), Sapelnikova, Svetlana2 (AUTHOR) ssapelnikova@kmthepatech.com, Tyrrell, D. Lorne2,3 (AUTHOR), Kneteman, Norman M.2,3,4 (AUTHOR)
Publikováno v:
Xenobiotica. Feb2014, Vol. 44 Issue 2, p109-122. 14p.