Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Garry Boag"'
Autor:
Nerime Chinner, Adel F. M. Ibrahim, Irene M. Leigh, Amit K. Garg, Mark K. Saville, Charlotte M. Proby, Lydia A. Hepburn, Angela McHugh, Garry Boag, Kenneth Fernandes
Publikováno v:
The Journal of Investigative Dermatology
We performed a small interfering RNA screen to identify targets for cutaneous squamous cell carcinoma (cSCC) therapy in the ubiquitin/ubiquitin-like system. We provide evidence for selective anti-cSCC activity of knockdown of the E3 ubiquitin ligase
Autor:
Lydia A, Hepburn, Angela, McHugh, Kenneth, Fernandes, Garry, Boag, Charlotte M, Proby, Irene M, Leigh, Mark K, Saville
Publikováno v:
Oncotarget
We show that suppression of the spliceosome has potential for the treatment of cutaneous squamous cell carcinoma (cSCC). The small-molecule inhibitors of the spliceosome at the most advanced stage of development target the splicing factor SF3B1/SF3b1