BCR::ABL1kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib

Autor: Leyte-Vidal, Ariel, Garrido Ruiz, Diego, DeFilippis, RosaAnna, Leske, Inga B., Rea, Delphine, Phan, Stacey, Miller, Kaeli B., Hu, Feifei, Mase, Anjeli, Shan, Yibing, Hantschel, Oliver, Jacobson, Matthew P., Shah, Neil P.

Publikováno v: Blood; August 2024, Vol. 144 Issue: 6 p639-645, 7p

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Computational studies of pH sensing design principles in proteins

Autor: Garrido Ruiz, Diego

Publikováno v: Garrido Ruiz, Diego. (2017). Computational studies of pH sensing design principles in proteins. UC San Francisco: Biophysics. Retrieved from: http://www.escholarship.org/uc/item/0k0350df

Changes in pH are important regulatory signals for biological function, under physiological and pathological conditions. Recent advances in computer simulations strategies have made the exploration of the effects of charge titrations on protein funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ecc47392e0a48ded034319270b6ee43b
http://www.escholarship.org/uc/item/0k0350df

The synthesis and structural requirements for measuring glucocorticoid receptor expression in vivo with (±)-¹¹C-YJH08 PET.

Autor: Huang, Yangjie, Zhao, Ning, Wang, Yung-hua, Truillet, Charles, Wei, Junnian, Parker, Matthew F. L., Blecha, Joseph E., Drake, Christopher R., VanBrocklin, Henry F., Garrido-Ruiz, Diego, Jacobson, Matthew P., Aggarwal, Rahul, Behr, Spencer C., Flavell, Robert R., Wilson, David M., Seo, Youngho, Evans, Michael J.

Publikováno v: Journal of Nuclear Medicine; Oct2020, Vol. 61 Issue 10, p1-1, 57p

Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium.

Autor: Pikman Y; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Kimberly_stegmaier@dfci.harvard.edu Yana_pikman@dfci.harvard.edu.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts., Tasian SK; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Pediatrics and Abramson Cancer Center at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Sulis ML; Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, Columbia University Irving Medical Center, New York, New York.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Stevenson K; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts., Blonquist TM; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts., Apsel Winger B; Department of Pediatrics, Division of Hematology/Oncology, Benioff Children's Hospital and the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Cooper TM; Seattle Children's Hospital, Cancer and Blood Disorders Center, Seattle, Washington., Pauly M; Division of Hematology/Oncology, Emory University, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia., Maloney KW; Children's Hospital Colorado, University of Colorado Cancer Center, Aurora, Colorado., Burke MJ; Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, Wisconsin., Brown PA; Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland., Gossai N; Center for Cancer and Blood Disorders, Children's Minnesota, Minneapolis, Minnesota., McNeer JL; University of Chicago, Comer Children's Hospital, Chicago, Illinois., Shukla NN; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Cole PD; Children's Hospital at Montefiore, Bronx, New York.; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Kahn JM; Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, Columbia University Irving Medical Center, New York, New York., Chen J; Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, Columbia University Irving Medical Center, New York, New York.; Children's Cancer Institute, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, New Jersey., Barth MJ; Roswell Park Comprehensive Cancer Center, Buffalo, New York., Magee JA; Division of Pediatric Hematology/Oncology, Washington University/St. Louis Children's Hospital, St. Louis, Missouri., Gennarini L; Children's Hospital at Montefiore, Bronx, New York., Adhav AA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Clinton CM; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Ocasio-Martinez N; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gotti G; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Li Y; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Lin S; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Imamovic A; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts., Tognon CE; Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon., Patel T; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Faust HL; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Contreras CF; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Cremer A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; University Hospital Frankfurt, Department of Hematology/Oncology, Frankfurt/Main, Germany., Cortopassi WA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California., Garrido Ruiz D; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California., Jacobson MP; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California., Dharia NV; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts., Su A; INSERM UMR 944, IRSL, St Louis Hospital, Paris, France., Robichaud AL; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Saur Conway A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Tarlock K; Seattle Children's Hospital, Cancer and Blood Disorders Center, Seattle, Washington., Stieglitz E; Department of Pediatrics, Division of Hematology/Oncology, Benioff Children's Hospital and the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Place AE; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts., Puissant A; INSERM UMR 944, IRSL, St Louis Hospital, Paris, France., Hunger SP; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Pediatrics and Abramson Cancer Center at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Kim AS; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Lindeman NI; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Gore L; Children's Hospital Colorado, University of Colorado Cancer Center, Aurora, Colorado., Janeway KA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts., Silverman LB; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts., Tyner JW; Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon., Harris MH; Department of Pathology, Boston Children's Hospital, Boston, Massachusetts., Loh ML; Department of Pediatrics, Division of Hematology/Oncology, Benioff Children's Hospital and the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Kimberly_stegmaier@dfci.harvard.edu Yana_pikman@dfci.harvard.edu.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts.

Publikováno v: Cancer discovery [Cancer Discov] 2021 Jun; Vol. 11 (6), pp. 1424-1439. Date of Electronic Publication: 2021 Feb 09.