Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors

Autor: Baladi, Tom, Aziz, Jessy, Dufour, Florent, Abet, Valentina, Stoven, Véronique, Radvanyi, François, Poyer, Florent, Wu, Ting-Di, Guerquin-Kern, Jean-Luc, Bernard-Pierrot, Isabelle, Garrido, Sergio Marco, Piguel, Sandrine

Publikováno v: Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2018, 26 (20), pp.5510-5530

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::c32c016848e61cc33b3d11d9d10ef335
https://hal.archives-ouvertes.fr/hal-01986358

Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors.

Autor: Baladi T; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France; Université Paris Sud, Université Paris-Saclay, F-91405 Orsay, France., Aziz J; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France., Dufour F; Institut Curie, PSL Research University, CNRS, UMR 144, F-75248 Paris 05, France., Abet V; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France., Stoven V; Institut Curie, PSL Research University, INSERM U900, F-75248 Paris 05, France; Mines ParisTech, CBIO - Centre for Computational Biology, 35 rue Saint-Honoré, F-77300 Fontainebleau, France., Radvanyi F; Institut Curie, PSL Research University, CNRS, UMR 144, F-75248 Paris 05, France., Poyer F; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France., Wu TD; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France., Guerquin-Kern JL; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France., Bernard-Pierrot I; Institut Curie, PSL Research University, CNRS, UMR 144, F-75248 Paris 05, France., Garrido SM; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France., Piguel S; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France; Université Paris Sud, Université Paris-Saclay, F-91405 Orsay, France. Electronic address: sandrine.piguel@curie.fr.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Nov 01; Vol. 26 (20), pp. 5510-5530. Date of Electronic Publication: 2018 Sep 25.