Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Garrick K. Wilson"'
Autor:
Claire L. Brimacombe, Garrick K. Wilson, Stefan G. Hübscher, Jane A. McKeating, Michelle J. Farquhar
Publikováno v:
Viruses, Vol 6, Iss 3, Pp 1454-1472 (2014)
Tetraspanins are a family of small proteins that interact with themselves, host transmembrane and cytosolic proteins to form tetraspanin enriched microdomains (TEMs) that regulate important cellular functions. Several tetraspanin family members are l
Externí odkaz:
https://doaj.org/article/362654fd7eb84bb08aa1412d327b43ad
Autor:
Garrick K. Wilson, Zania Stamataki
Publikováno v:
International Journal of Hepatology, Vol 2012 (2012)
The study of a virus is made possible by the availability of culture systems in which the viral lifecycle can be realized. Such systems support robust virus entry, replication, assembly, and secretion of nascent virions. Furthermore, culture models p
Externí odkaz:
https://doaj.org/article/5af7bd86b8454f34842d7d8510a1d7d4
Autor:
Christopher J. Mee, Markus H. Heim, Patrick Pessaux, Erika Girardi, Sébastien Pfeffer, Christopher Davis, Simonetta Bandiera, Isabel Fofana, Ralf Bartenschlager, Lars Kaderali, Koen Vercauteren, Diego Calabrese, Laurent Mailly, Céline Leboeuf, Nicola F. Fletcher, Maura Dandri, Pascal Villa, Helen J. Harris, Tassilo Volz, Mirjam B. Zeisel, Fei Xiao, Michel Neunlist, Eric Robinet, Marc Lütgehetmann, Béatrice Chane-Woon-Ming, Philip Meuleman, Jane A. McKeating, Thomas F. Baumert, Maria Ericsson, Joachim Lupberger, Garrick K. Wilson, Francois H.T. Duong, Philippe Aubert, Christine Thumann
Publikováno v:
Nature biotechnology
Nature Biotechnology
Nature Biotechnology, 2015, 33 (5), pp.549-554. ⟨10.1038/nbt.3179⟩
Nature Biotechnology, Nature Publishing Group, 2015, 33 (5), pp.549-554. ⟨10.1038/nbt.3179⟩
Nature Biotechnology
Nature Biotechnology, 2015, 33 (5), pp.549-554. ⟨10.1038/nbt.3179⟩
Nature Biotechnology, Nature Publishing Group, 2015, 33 (5), pp.549-554. ⟨10.1038/nbt.3179⟩
Hepatitis C virus (HCV) infection is a leading cause of liver cirrhosis and cancer. Cell entry of HCV and other pathogens is mediated by tight junction (TJ) proteins, but successful therapeutic targeting of TJ proteins has not been reported yet. Usin
Autor:
David Greenald, Francesco Argenton, Margherita Peron, Eleanor Markham, Mathavan Sinnakaruppan, Jane A. McKeating, Garrick K. Wilson, Laura Matthews, Andrea Vettori, Fredericus J.M. van Eeden, Nicola Facchinello
Glucocorticoid (GC) and hypoxic transcriptional responses play a central role in tissue homeostasis and regulate the cellular response to stress and inflammation, highlighting the potential for cross-talk between these two signaling pathways. We pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7d2bc81da4adecb9117a596d26ae0c
http://hdl.handle.net/11577/3249028
http://hdl.handle.net/11577/3249028
Autor:
Catalin Lazar, Roy Bicknell, Sarah Durant, Richard D. Parker, Norica Branza-Nichita, David H. Adams, Ian A. Rowe, Sukhdeep Kaur Galsinh, Jane A. McKeating, Peter Balfe, Garrick K. Wilson
Publikováno v:
Hepatology. 59:375-384
Hepatitis C virus (HCV) is a major cause of global morbidity, causing chronic liver injury that can progress to cirrhosis and hepatocellular carcinoma. The liver is a large and complex organ containing multiple cell types, including hepatocytes, sinu
Autor:
Nicola F. Fletcher, Jane A. McKeating, Peter Balfe, Garrick K. Wilson, Luke W. Meredith, Helen J. Harris
Publikováno v:
Journal of Hepatology. 58:1074-1080
Background & Aims Hepatitis C virus (HCV) poses a global health problem, with over 170million chronically infected individuals at risk of developing progressive liver disease. The ability of a virus to spread within a host is a key determinant of its
Autor:
Peter Balfe, Patrice Dosset, Helen J. Harris, Michelle J. Farquhar, Garrick K. Wilson, Margaret Goodall, S. C. IJzendoorn, Jane A. McKeating, Caroline Clerté, Ke Hu, Pierre-Emmanuel Milhiet, Patrice Rassam
Publikováno v:
Cellular Microbiology; Vol 15
Cellular Microbiology
Cellular Microbiology, 15(3), 430-445. Wiley-Blackwell
Cellular Microbiology
Cellular Microbiology, 15(3), 430-445. Wiley-Blackwell
Many viruses target the polarized epithelial apex during host invasion. In contrast, hepatitis C virus (HCV) engages receptors at the basal surface of hepatocytes in the polarized liver parenchyma. Hepatocyte polarization limits HCV entry by undefine
Autor:
Michael J.O. Wakelam, Jane A. McKeating, Thomas F. Baumert, Simon A. Rudge, Maria Ciaccia, Laurent Mailly, Ke Hu, Margaret Ashcroft, Isla S. Humphreys, Stephanie Roessler, Bishnupriya Bhattacharya, Qifeng Zhang, Garrick K. Wilson, Michelle J. Farquhar, Gary M. Reynolds, Peter Balfe
Publikováno v:
Journal of Hepatology
Journal of Hepatology, Elsevier, 2017, 66 (5), pp.919-929. ⟨10.1016/j.jhep.2017.01.009⟩
Journal of Hepatology, Elsevier, 2017, 66 (5), pp.919-929. ⟨10.1016/j.jhep.2017.01.009⟩
BACKGROUND AND AIMS: Chronic hepatitis C is a global health problem with an estimated 170 million HCV infected individuals at risk of progressive liver disease and hepatocellular carcinoma (HCC). Autotaxin (ATX) is a phospholipase with diverse roles
Autor:
Daniel A, Patten, Garrick K, Wilson, Dalan, Bailey, Robert K, Shaw, Sirpa, Jalkanen, Marko, Salmi, Antal, Rot, Chris J, Weston, David H, Adams, Shishir, Shetty
Publikováno v:
Hepatology (Baltimore, Md.)
The recruitment of lymphocytes via the hepatic sinusoidal channels and positioning within liver tissue is a critical event in the development and persistence of chronic inflammatory liver diseases. The hepatic sinusoid is a unique vascular bed lined
Publikováno v:
Reviews in Medical Virology. 22:182-193
HCV is a blood-borne pathogen that affects approximately 3% of the global population and leads to progressive liver disease. Recent advances have identified an essential role for host cell molecules: tetraspanin CD81, scavenger receptor B1 and the ti