Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Garrett E. Berry"'
Autor:
Dasean Nardone-White, Aravind Asokan, Zachary C. Elmore, Jonathan Ark, Tyne O. Tyson, Giridhar Murlidharan, Heather A. Vincent, Garrett E. Berry, Victoria J. Madigan
Publikováno v:
Journal of Virology
Adeno-associated viruses (AAVs) have proven to be effective gene transfer vectors. However, our understanding of how the host cell environment influences AAV transduction is still evolving. In the present study, we investigated the role of ATP2C1, wh
Autor:
Giridhar Murlidharan, Garrett E. Berry, Ruth M. Castellanos Rivera, Blake H. Albright, Claire M. Storey, Victoria J. Madigan, Aravind Asokan
Publikováno v:
Molecular Therapy. 26:510-523
Effective gene delivery to the CNS by intravenously administered adeno-associated virus (AAV) vectors requires crossing the blood-brain barrier (BBB). To achieve therapeutic CNS transgene expression, high systemic vector doses are often required, whi
Autor:
Aravind Asokan, Garrett E. Berry
Publikováno v:
Current Opinion in Virology. 21:54-60
Recombinant adeno-associated viral vectors (rAAV) are regarded as promising vehicles for therapeutic gene delivery. Continued development and new strategies are essential to improve the potency of AAV vectors and reduce the effective dose needed for
Autor:
Garrett E. Berry, Longping V. Tse
The binding and internalization of adeno-associated virus (AAV) is an important determinant of viral infectivity and tropism. The ability to dissect these two tightly connected cellular processes would allow better understanding and provide insight o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26f3dd7b79d3581c154842098c4b94b
https://europepmc.org/articles/PMC5718205/
https://europepmc.org/articles/PMC5718205/
Autor:
Tony L. Goldberg, Patrick M. Muzzall, Jeffrey D. Brawn, Gabriel L. Hamer, Garrett E. Berry, Marilyn O. Ruiz, Edward D. Walker, Amanda C. Dolinski, Jeffrey C. Crafton, Tavis K. Anderson, Bethany L. Krebs, Alvin Makohon-Moore
Publikováno v:
International Journal for Parasitology: Parasites and Wildlife
Graphical abstract Highlights ► Co-circulating hematozoan parasites in avian amplification hosts for West Nile virus. ► Hematocrit centrifuge technique for microfilariae and trypanosomes. ► Phylogenetics describe community composition of filari
Autor:
Aravind Asokan, Garrett E. Berry
Publikováno v:
Journal of Biological Chemistry
Intracellular trafficking of viruses can be influenced by a variety of inter-connected cellular sorting and degradation pathways involving endo-lysosomal vesicles, the ubiquitin-proteasome system, and autophagy-based or endoplasmic reticulum-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e93a99f70112861e5d28d7dd2fd331e
Autor:
Stéphanie Laprise, Alice Y Chou, Aravind Asokan, Elodie Portales-Casamar, Wyeth W. Wasserman, Lisa J. Borretta, Vikramjit Chopra, Olga Kaspieva, George S. Yang, Dan Goldowitz, Cletus D'Souza, Elizabeth M. Simpson, Robert A. Holt, Magdalena I. Swanson-Newman, Michelle Zhou, Siu Ling Lam, Kaelan Wong, Andrea J. Korecki, Jack W. Hickmott, Simone C McInerny, Russell J. Bonaguro, Tess C Lengyell, Garrett E. Berry, Steven J.M. Jones, Charles N. de Leeuw
Publikováno v:
Molecular Brain
Background: Small promoters that recapitulate endogenous gene expression patterns are important for basic, preclinical, and now clinical research. Recently, there has been a promising revival of gene therapy for diseases with unmet therapeutic needs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cfa6eab0b5067556b82bc274888153
Autor:
Matthew Ordidge, Philip L. Forsline, Muraleedharan G. Nair, R. Michelutti, Nihad Alsmairat, Margie Luffman, Steven van Nocker, Randy Beaudry, Garrett E. Berry, James Najdowski
Publikováno v:
Euphytica. 185:281-293
Anthocyanins are flavonoid pigments imparting red, blue, or purple pigmentation to fruits, flowers and foliage. These compounds are powerful antioxidants in vitro, and are widely believed to contribute to human health. The fruit of the domestic apple
Autor:
Aravind Asokan, Garrett E. Berry
Publikováno v:
Molecular Therapy. 23
Vector dose-related toxicity has been highlighted as a potential safety concern in recent preclinical studies and clinical trials with recombinant AAV vectors. Thus, investigation of strategies to enhance AAV transduction may allow for administration
Autor:
Ruth M. Castellanos Rivera, Roland Cheung, Aravind Asokan, Sarah M. Brown, Andrew N. Troupes, Shen Shen, Tal Kafri, Garrett E. Berry
Publikováno v:
The Journal of biological chemistry. 290(3)
Adeno-associated viruses (AAVs) display a highly conserved NGR motif on the capsid surface. Earlier studies have established this tripeptide motif as being essential for integrin-mediated uptake of recombinant AAV serotype 2 (AAV2) in cultured cells.