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pro vyhledávání: '"Garrett A Enten"'
Autor:
McWayne Weche, Anthony J DeSantis, Michelle Y McGee, Garrett A Enten, Xianlong Gao, Matthias Majetschak
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284472 (2023)
Systemic concentrations of chemokine CCL2, an agonist at chemokine receptors CCR2/3/5, have been associated with hemodynamic instability after traumatic-hemorrhagic shock. We reported previously that the CCR2 antagonist INCB3284 prevents cardiovascul
Externí odkaz:
https://doaj.org/article/07d89c8c650f447ba74b500f85856555
Autor:
Anthony J. DeSantis, MD, McWayne Weche, MD, Garrett A. Enten, MS, Xianlong Gao, MD, PhD, Matthias Majetschak, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 5, p e0701 (2022)
OBJECTIVES:. Clinical correlations suggest that systemic chemokine (C-C motif) ligand (CCL) 2 release may contribute to blood pressure regulation and the development of hemodynamic instability during the early inflammatory response to traumatic-hemor
Externí odkaz:
https://doaj.org/article/112e5460702a4fdf96f1b6d272f7f10b
Autor:
Xianlong Gao, Anthony J. DeSantis, Garrett A. Enten, McWayne Weche, Jorge E. Marcet, Matthias Majetschak
Publikováno v:
FEBS Letters. 596:2706-2716
Autor:
Xianlong, Gao, Anthony J, DeSantis, Garrett A, Enten, McWayne, Weche, Jorge E, Marcet, Matthias, Majetschak
Publikováno v:
FEBS lettersReferences. 596(20)
Previously, we reported that chemokine (C-C motif) receptor 2 (CCR2) heteromerizes with α
Publikováno v:
Pharmacological Research. 190:106730
Autor:
Garrett A, Enten, Xianlong, Gao, Hannah R, Strzelinski, McWayne, Weche, Stephen B, Liggett, Matthias, Majetschak
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(20)
It is known that catecholamines regulate innate immune functions. The underlying mechanisms, however, are not well understood. Here we show that at least 20 members of the human chemokine receptor (CR) family heteromerize with one or more members of
Autor:
Garrett A. Enten, Xianlong Gao, Hannah R. Strzelinski, McWayne Weche, Stephen B. Liggett, Matthias Majetschak
Publikováno v:
Proceedings of the National Academy of Sciences. 119
SignificanceHere we show that most chemokine receptors (CRs) form heteromeric complexes with α1-adrenergic receptors (ARs) in recombinant systems and that such heteromers are detectable in human monocytes and in the human monocytic leukemia cell lin
Autor:
Xianlong, Gao, You-Hong, Cheng, Garrett A, Enten, Anthony J, DeSantis, Vadim, Gaponenko, Matthias, Majetschak
Publikováno v:
J Biol Chem
The chemokine receptor CXCR4, a G protein–coupled receptor (GPCR) capable of heteromerizing with other GPCRs, is involved in many processes, including immune responses, hematopoiesis, and organogenesis. Evidence suggests that CXCR4 activation reduc
Autor:
Xianlong, Gao, Garrett A, Enten, Anthony J, DeSantis, Brian F, Volkman, Vadim, Gaponenko, Matthias, Majetschak
Publikováno v:
Biochem Biophys Res Commun
Recently, we reported that chemokine (C-X-C motif) receptor 4 (CXCR4) heteromerizes with α(1)-adrenergic receptors (AR) on the cell surface of vascular smooth muscle cells, through which the receptors cross-talk. Direct biophysical evidence for CXCR