Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Garreth L, Morgans"'
Autor:
Robin Klintworth, Garreth L. Morgans, Stefania M. Scalzullo, Charles B. de Koning, Willem A. L. van Otterlo, Joseph P. Michael
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2543-2552 (2021)
A wide range of N-(ethoxycarbonylmethyl)enaminones, prepared by the Eschenmoser sulfide contraction between N-(ethoxycarbonylmethyl)pyrrolidine-2-thione and various bromomethyl aryl and heteroaryl ketones, underwent cyclization in the presence of sil
Externí odkaz:
https://doaj.org/article/558c40a85b1b44bb94abcce7bcfdbec2
Publikováno v:
Arkivoc. 2020:4-23
Autor:
Charles B. de Koning, Joseph P. Michael, Garreth L. Morgans, Robin Klintworth, Willem A. L. van Otterlo, Stefania M. Scalzullo
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2543-2552 (2021)
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2543-2552 (2021)
A wide range of N-(ethoxycarbonylmethyl)enaminones, prepared by the Eschenmoser sulfide contraction between N-(ethoxycarbonylmethyl)pyrrolidine-2-thione and various bromomethyl aryl and heteroaryl ketones, underwent cyclization in the presence of sil
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 12, Pp o3281-o3281 (2012)
The title compound, C21H21NO, is a vinylogous amide (enaminone) produced by reaction of 1-(2-phenylprop-2-en-1-yl)pyrrolidine-2-thione with phenacyl bromide. In the molecule, the phenyl rings are twisted from the mean plane of the pyrrolidine ring by
Externí odkaz:
https://doaj.org/article/23094131dcf84243acf05f23a1375a38
Publikováno v:
European Journal of Organic Chemistry. 2018:1902-1909
Autor:
Joseph P. Michael, Garreth L. Morgans, Willem A. L. van Otterlo, Ivan R. Green, Blessing A. Aderibigbe, Tanya Mabank, Mari Janse van Rensburg, Manuel A. Fernandes
Publikováno v:
Tetrahedron. 73:4671-4683
A set of benzo-fused dienes with a 1,9-relationship and containing a variety of nitrogen and oxygen heteroatoms was readily synthesized. These dienes were then treated with the Grubbs second generation catalyst with the aim of synthesizing the 9-memb
Autor:
Biljana Marjanovic-Painter, Molahlehi S. Sonopo, Susan Winks, Kobus Venter, Garreth L. Morgans, Jan Rijn Zeevaart
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 59:264-269
This paper describes a five-step synthesis of a carbon-14-labelled pyrazole compound (11). A total of 2.96 MBq of 11 was obtained with the specific activity of 2242.4 MBq/mmol. The radiochemical purity was >99%, and the overall radiochemical yield wa
Autor:
Digby F. Warner, Krupa Naran, Nina Lawrence, Helena I. Boshoff, Renier van der Westhuyzen, Atica Moosa, Richard Gordon, Clifton E. Barry, Kelly Chibale, Tzu-Shean Feng, Leslie J. Street, C. John Harris, Garreth L. Morgans, Richard K. Gessner, Candice Soares de Melo
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:7240-7250
Whole-cell high-throughput screening of a diverse SoftFocus library against Mycobacterium tuberculosis (Mtb) generated a novel aminopyrazolo[1,5-a]pyrimidine hit series. The synthesis and structure activity relationship studies identified compounds w
Autor:
Vincent J. Smith, Willem A. L. van Otterlo, Manuel A. Fernandes, Leandi van der Westhuizen, Garreth L. Morgans, Abu Taher, Lee G. Madeley, Setshaba D. Khanye, Blessing A. Aderibigbe, Ivan R. Green, Joseph P. Michael
Publikováno v:
Tetrahedron. 69:2038-2047
A set of eight-membered benzannelated heterocycles containing two heteroatoms (O,O, NR,NR and O,NR where R=protecting group) was synthesized by ring-closing metathesis from the corresponding ortho-bis-allyl precursors. In this manner, 7-methoxy-2,5-d
Autor:
Joseph P. Michael, Manuel A. Fernandes, Garreth L. Morgans, Willem A. L. van Otterlo, Charles B. de Koning, Dharmendra B. Yadav
Publikováno v:
Tetrahedron Letters. 53:2384-2387
Application of sub-stoichiometric amounts of Grubbs’ second generation catalyst to the substrate N-allyl-N-[2-(allylsulfanyl)phenyl]-4-methylbenzenesulfonamide afforded the ring-closed compound 6-[(4-methylphenyl)sulfonyl]-5,6-dihydro-2H-1,6-benzot