Výsledky vyhledávání - "Garreth Kestell"

CGRPα within the Trpv1-Cre population contributes to visceral nociception

Autor: David C. Morris, Jon E. T. Jakobsson, Garreth Kestell, Simon J. H. Brookes, Elín Ingibjörg Magnúsdóttir, Malin C. Lagerström, Bao Nan Chen, Nick J. Spencer

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 314:G188-G200

The role of calcitonin gene-related peptide (CGRP) in visceral and somatic nociception is incompletely understood. CGRPα is highly expressed in sensory neurons of dorsal root ganglia and particularly in neurons that also express the transient recept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695e04d7c16310be8626b6634ab0ab8d
https://doi.org/10.1152/ajpgi.00188.2017

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Primary afferent neurons containing calcitonin gene-related peptide but not substance P in forepaw skin, dorsal root ganglia, and spinal cord of mice

Autor: Rainer Viktor Haberberger, Ian L. Gibbins, Rebecca L. Anderson, Jennifer N. Clarke, Garreth Kestell

Publikováno v: Journal of Comparative Neurology. 523:2555-2569

In mice dorsal root ganglia (DRG), some neurons express calcitonin gene-related peptide (CGRP) without substance P (SP; CGRP(+) SP(-) ). The projections and functions of these neurons are unknown. Therefore, we combined in vitro axonal tracing with m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a73acc31907e751832ee9b7e0a899de3
https://doi.org/10.1002/cne.23804

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Sensory nerve fibers containing calcitonin gene-related peptide in gastrocnemius, latissimus dorsi and erector spinae muscles and thoracolumbar fascia in mice

Autor: Christine Barry, Rainer Viktor Haberberger, Garreth Kestell, Maeve Gillan, Ian L. Gibbins

Publikováno v: Neuroscience. 291:106-117

Chronic pain is a significant burden and much is attributed to back muscles. Back muscles and their associated fasciae make important and distinct contributions to back pain. Peptidergic nociceptors innervating these structures contribute to central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30c0c931dcb68b185832a395d1ce676
https://doi.org/10.1016/j.neuroscience.2015.01.062

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Identification of different functional types of spinal afferent neurons innervating the mouse large intestine using a novel CGRPα transgenic reporter mouse

Autor: Garreth Kestell, Simon J. H. Brookes, Timothy J. Hibberd, David Wattchow, Melinda Kyloh, Nick J. Spencer

Publikováno v: American journal of physiology. Gastrointestinal and liver physiology. 310(8)

Spinal afferent neurons detect noxious and physiological stimuli in visceral organs. Five functional classes of afferent terminals have been extensively characterized in the colorectum, primarily from axonal recordings. Little is known about the corr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe15e502725baadbb593df7a1410167
https://pubmed.ncbi.nlm.nih.gov/26822917

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