Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Garret Hampton"'
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
PDF file 155K, Principal component analysis (PCA) of the ten biomarkers provides a biomarker profile for each cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9160c26f5bad4b3038a3fecf717ba525
https://doi.org/10.1158/1078-0432.22447095.v1
https://doi.org/10.1158/1078-0432.22447095.v1
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
PDF file 285K, Biomarker validation by Western blot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7ff0200ee6aff7a9a27cf061848187
https://doi.org/10.1158/1078-0432.22447098.v1
https://doi.org/10.1158/1078-0432.22447098.v1
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
PDF file 252K, In vivo pharmacodynamic IHC-based biomarker dose-response quantifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61770fe46df1bb0c1fae8efd035d7cc0
https://doi.org/10.1158/1078-0432.22447092
https://doi.org/10.1158/1078-0432.22447092
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
PDF file 64K, Unsupervised clustering of the core biomarker modulation in cell lines, xenograft tumors, and in tumors from three patients in the 100mg cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1845592352befd7edb5d09fb04872dba
https://doi.org/10.1158/1078-0432.22447086
https://doi.org/10.1158/1078-0432.22447086
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
PDF file 168K, Pearson and Spearman correlation with survival fraction for all cell lines together or individual cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5858aedb01bc8923a0ed9d194edb193
https://doi.org/10.1158/1078-0432.22447074.v1
https://doi.org/10.1158/1078-0432.22447074.v1
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
XLS file 37K, RPPA quantification of laser captured microscopy needle biopsies in patients from the 100mg cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70fcb93d2b650fce4f595eb5cdd1ab0
https://doi.org/10.1158/1078-0432.22447068
https://doi.org/10.1158/1078-0432.22447068
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
Purpose: The oncogenic PI3K/Akt/mTOR pathway is an attractive therapeutic target in cancer. However, it is unknown whether the pathway blockade required for tumor growth inhibition is clinically achievable. Therefore, we conducted pharmacodynamic stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a49a53c12f67131e7b506ce01be33c
https://doi.org/10.1158/1078-0432.c.6520965.v1
https://doi.org/10.1158/1078-0432.c.6520965.v1
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
PDF file 161K, Tumor PIK3CA and PTEN status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2a29a5aeeb780434d8c026d4f47401
https://doi.org/10.1158/1078-0432.22447071.v1
https://doi.org/10.1158/1078-0432.22447071.v1
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
XLS file 41K, RPPA biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ce8881aa418a8e57bd48c7f32e78e8
https://doi.org/10.1158/1078-0432.22447083
https://doi.org/10.1158/1078-0432.22447083
Autor:
José Baselga, Premal Patel, Josep Tabernero, Andrés Cervantes, Desamparados Roda, Cristina Saura, Mark R. Lackner, Vanitha Ramakrishnan, Garret Hampton, Matthew Wongchenko, Jenny Q. Wu, Marie-Claire Wagle, Yuanyuan Xiao, Michelle Nannini, Deepak Sampath, Marta Guzman, Olga Rodríguez, Sumati Murli, Maurizio Scaltriti, Ludmila Prudkin, Violeta Serra, Yibing Yan
PDF file 117K, Supplementary Materials and Methods -Supplementary Figure Legends -Supplementary Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a95f4f05e583b12068d32fe1cb3a12
https://doi.org/10.1158/1078-0432.22447101
https://doi.org/10.1158/1078-0432.22447101