Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

Autor: Montalban, X., Hauser, S. L., Kappos, L., Arnold, D. L., Bar‑or, A., Comi, G., de Seze, J., Giovannoni, G., Hartung, H. -P., Hemmer, B., Lublin, F., Rammohan, K. W., Selmaj, K., Traboulsee, A., Sauter, A., Masterman, D., Fontoura, P., Belachew, S., Garren, H., Mairon, N., Chin, P., Wolinsky, J. S., Uccelli, A, for the ORATORIO Clinical Investigators

Publikováno v: New England Journal of Medicine, 376(3), 209-220. MASSACHUSETTS MEDICAL SOCIETY
Scientia
New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2017, 376 (3), pp.209-220. ⟨10.1056/NEJMoa1606468⟩

Ocrelizumab; Placebo; Multiple sclerosis Ocrelizumab; Placebo; Esclerosi múltiple Ocrelizumab; Placebo; Esclerosis múltiple BACKGROUND: An evolving understanding of the immunopathogenesis of multiple sclerosis suggests that depleting B cells could

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ff017958f659651759d3a1762d862a
https://doi.org/10.1056/nejmoa1606468

3,4-DAA, an orally active synthetic tryptophan catabolite, treats established autoimmune neuroinflammation

Autor: Platten, M, Ho, P, Youssef, S, Garren, H, Fontoura, P, Sobel, R, Selley, M, Steinman, L

Publikováno v: Aktuelle Neurologie; 20240101, Issue: Preprints

Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8(+) T Cells in Type 1 Diabetes

Autor: Roep, B.O., Solvason, N., Gottlieb, P.A., Abreu, J.R.F., Harrison, L.C., Eisenbarth, G.S., Yu, L.P., Leviten, M., Hagopian, W.A., Buse, J.B., Herrath, M. von, Quan, J., King, R.S., Robinson, W.H., Utz, P.J., Garren, H., Steinman, L., BHT-3021 Investigators

Publikováno v: Science Translational Medicine, 5(191)

In type 1 diabetes (T1D), there is an intense inflammatory response that destroys the β cells in the pancreatic islets of Langerhans, the site where insulin is produced and released. A therapy for T1D that targets the specific autoimmune response in

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http://hdl.handle.net/1887/102545

P 1 Effect of ocrelizumab on magnetic resonance imaging markers of neurodegeneration in patients with relapsing multiple sclerosis – analysis of the phase III, double-blind, double-dummy, interferon beta-1a- controlled OPERA I and OPERA II studies

Autor: Ziemssen, T., Arnold, D.L., Bar-Or, A., Comi, G., Hartung, H.P., Hauser, S.L., Kappos, L., Lublin, F., Selmaj, K., Traboulsee, A., Masterman, D., Chin, P., Garren, H., Wolinsky, J.S.

Publikováno v: In Clinical Neurophysiology October 2017 128(10):e326-e326

2006 Rare Neuroimmunological Disorders Symposium; Sheraton Inner Harbor, Baltimore, MD, July 20-23, 2006

Autor: Kerr, DA, Antel, JP, Arnold, DL, Bach, JF, Balcer, LJ, Amit, BO, Bielekova, B, Brück, W, Calabresi, PA, Christensen, Tove, Conant, KE, Dalmau, J, Deshpande, DM, Dhib-Jalbut, S, Drummond, J, Franklin, R, Garren, H, Goverman, JM, Hauser, S, Jacobson, S, Kaplin, AI, Kim, YS, Krishnan, S, Lipton, SA, Lucchinetti, C, Martinez, T, Major, E, Nath, AA, Nayak, MM, Pavlov, V, Pelletier, D, Provost-Javier, K, Pucak, ML, Racke, MK, Ransohoff, RM, Rao, MS, Reich, D, Rosen, A, Rus, HG, Sandrock, AW, Schwartz, M, Sheikh, KA, Smith, S, Sur, S, Trapp, BD, Weinshenker, BG, Wingerchuk, DM, Yong, VW

Publikováno v: Kerr, DA, Antel, JP, Arnold, DL, Bach, JF, Balcer, LJ, Amit, BO, Bielekova, B, Brück, W, Calabresi, PA, Christensen, T, Conant, KE, Dalmau, J, Deshpande, DM, Dhib-Jalbut, S, Drummond, J, Franklin, R, Garren, H, Goverman, JM, Hauser, S, Jacobson, S, Kaplin, AI, Kim, YS, Krishnan, S, Lipton, SA, Lucchinetti, C, Martinez, T, Major, E, Nath, AA, Nayak, MM, Pavlov, V, Pelletier, D, Provost-Javier, K, Pucak, ML, Racke, MK, Ransohoff, RM, Rao, MS, Reich, D, Rosen, A, Rus, HG, Sandrock, AW, Schwartz, M, Sheikh, KA, Smith, S, Sur, S, Trapp, BD, Weinshenker, BG, Wingerchuk, DM & Yong, VW 2007, 2006 Rare Neuroimmunological Disorders Symposium; Sheraton Inner Harbor, Baltimore, MD, July 20-23, 2006 . in Journal of Neuroimmunology . vol. 189, pp. 1-6 .

On July 20-22nd 2006, the second International Rare Neuroimmunologic Disorders Symposium was held in Baltimore, Maryland. The purpose of this symposium was to bring together diverse groups interested in immune-mediated disorders of the nervous system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::b890271a5ee773d04d071511c43997f5
https://pure.au.dk/portal/da/publications/2006-rare-neuroimmunological-disorders-symposium-sheraton-inner-harbor-baltimore-md-july-2023-2006(20f109c0-77f6-11dc-bee9-02004c4f4f50).html