RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, EGFR-mutated, metastatic non-small cell lung cancer: Europe/United States subset analysis

Autor: Ponce Aix, S, Novello, S, Garon, EB, Nakagawa, K, Nadal, E, Moro-Sibilot, D, Alonso Garcia, M, Fabre, E, Frimodt-Moller, B, Zimmermann, AH, Visseren-Grul, CM, Reck, M

Publikováno v: In Cancer Treatment and Research Communications 2021 27

Multicenter trial of EC145 in advanced, folate-receptor positive adenocarcinoma of the lung.

Autor: Edelman MJ, Harb WA, Pal SE, Boccia RV, Kraut MJ, Bonomi P, Conley BA, Rogers JS, Messmann RA, Garon EB

Publikováno v: Journal of Thoracic Oncology; 2012 Oct, Vol. 7 Issue 10, p1618-1621, 4p

Targeting MEK for the treatment of non-small-cell lung cancer.

Autor: Goldman JW, Garon EB, Goldman, Jonathan W, Garon, Edward B

Publikováno v: Journal of Thoracic Oncology; 2012 Supplement, Vol. 7, pS377-8, 1p

CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors.

Autor: Skoulidis F; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. fskoulidis@mdanderson.org., Araujo HA; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Do MT; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Qian Y; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Sun X; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Cobo AG; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Le JT; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Montesion M; Foundation Medicine, Cambridge, MA, USA., Palmer R; Pionyr Immunotherapeutics, South San Francisco, CA, USA., Jahchan N; Pionyr Immunotherapeutics, South San Francisco, CA, USA., Juan JM; D2G Oncology, Mountain View, CA, USA., Min C; Tango Therapeutics, Boston, MA, USA., Yu Y; Tango Therapeutics, Boston, MA, USA., Pan X; Tango Therapeutics, Boston, MA, USA., Arbour KC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vokes N; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Schmidt ST; Department of Genomic Medicine and the Institute for Data Science in Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Molkentine D; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Owen DH; Division of Medical Oncology, Ohio State University-James Comprehensive Cancer Center, Columbus, OH, USA., Memmott R; Division of Medical Oncology, Ohio State University-James Comprehensive Cancer Center, Columbus, OH, USA., Patil PD; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA., Marmarelis ME; Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Murray JC; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hellyer JA; Department of Genetics, Stanford University, Stanford, CA, USA., Gainor JF; Massachussetts General Hospital, Boston, MA, USA., Dimou A; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Bestvina CM; Department of Medicine, University of Chicago, Chicago, IL, USA., Shu CA; Columbia University, New York, NY, USA., Riess JW; University of California Davis Comprehensive Cancer Center, Sacramento, CA, USA., Blakely CM; University of California San Francisco, San Francisco, CA, USA., Pecot CV; UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA., Mezquita L; Department of Medical Oncology, Hospital Clinic de Barcelona, Barcelona, Spain., Tabbó F; Ospedale Michele e Pietro Ferrero, Cuneo, Italy., Scheffler M; Department of Internal Medicine, Center for Integrated Oncology, University Hospital Cologne, Cologne, Germany., Digumarthy S; Department of Radiology, Massachussetts General Hospital, Boston, MA, USA., Mooradian MJ; Massachussetts General Hospital, Boston, MA, USA., Sacher AG; Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Lau SCM; Department of Medical Oncology, NYU Langone Perlmutter Cancer Center, New York, NY, USA., Saltos AN; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Rotow J; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Johnson RP; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Liu C; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Stewart T; Division of Hematology-Oncology, University of California San Diego, La Jolla, CA, USA., Goldberg SB; Yale School of Medicine, New Haven, CT, USA., Killam J; North Shore University Hospital, Manhasset, NY, USA., Walther Z; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Schalper K; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Davies KD; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Woodcock MG; UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA., Anagnostou V; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Marrone KA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Forde PM; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Venkatraman D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Van Allen EM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Cummings AL; David Geffen School of Medicine at the University of California, Los Angeles, CA, USA., Goldman JW; David Geffen School of Medicine at the University of California, Los Angeles, CA, USA., Shaish H; Columbia University, New York, NY, USA., Kier M; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Katz S; Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Aggarwal C; Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Ni Y; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA., Azok JT; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA., Segal J; Department of Pathology, University of Chicago, Chicago, USA., Ritterhouse L; Foundation Medicine, Cambridge, MA, USA., Neal JW; Department of Genetics, Stanford University, Stanford, CA, USA., Lacroix L; Institut Gustave Roussy, Villejuif, France., Elamin YY; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Negrao MV; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Le X; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lam VK; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lewis WE; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kemp HN; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Carter B; Department of Thoracic Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Roth JA; Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Swisher S; Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lee R; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhou T; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Poteete A; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kong Y; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Takehara T; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Paula AG; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Parra Cuentas ER; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Behrens C; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wistuba II; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang J; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Blumenschein GR; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gay C; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Byers LA; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gibbons DL; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tsao A; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lee JJ; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Bivona TG; University of California San Francisco, San Francisco, CA, USA., Camidge DR; University of Colorado Cancer Center, Denver, CO, USA., Gray JE; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Lieghl N; Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Levy B; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Brahmer JR; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Garassino MC; Department of Medicine, University of Chicago, Chicago, IL, USA., Gandara DR; University of California Davis Comprehensive Cancer Center, Sacramento, CA, USA., Garon EB; David Geffen School of Medicine at the University of California, Los Angeles, CA, USA., Rizvi NA; Synthekine, Menlo Park, CA, USA., Scagliotti GV; University of Turin, Orbassano, Italy., Wolf J; Department of Internal Medicine, Center for Integrated Oncology, University Hospital Cologne, Cologne, Germany., Planchard D; Institut Gustave Roussy, Villejuif, France., Besse B; Institut Gustave Roussy, Villejuif, France., Herbst RS; Yale School of Medicine, New Haven, CT, USA., Wakelee HA; Department of Genetics, Stanford University, Stanford, CA, USA., Pennell NA; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA., Shaw AT; Novartis Institute for Biomedical Research, Cambridge, MA, USA., Jänne PA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Carbone DP; Division of Medical Oncology, Ohio State University-James Comprehensive Cancer Center, Columbus, OH, USA., Hellmann MD; AstraZeneca, Gaithersburg, MD, USA., Rudin CM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Albacker L; Foundation Medicine, Cambridge, MA, USA., Mann H; AstraZeneca, Cambridge, UK., Zhu Z; AstraZeneca, Cambridge, UK., Lai Z; AstraZeneca, Cambridge, UK., Stewart R; AstraZeneca, Cambridge, UK., Peters S; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland., Johnson ML; Sarah Cannon Research Institute, Tennessee Oncology, Nashville, TN, USA., Wong KK; Division of Hematology & Medical Oncology, NYU Langone Perlmutter Cancer Center, New York, NY, USA., Huang A; Tango Therapeutics, Boston, MA, USA., Winslow MM; D2G Oncology, Mountain View, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Rosen MJ; D2G Oncology, Mountain View, CA, USA., Winters IP; D2G Oncology, Mountain View, CA, USA., Papadimitrakopoulou VA; Pfizer, New York, NY, USA., Cascone T; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Jewsbury P; AstraZeneca, Cambridge, UK., Heymach JV; Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. jheymach@mdanderson.org.

Publikováno v: Nature [Nature] 2024 Nov; Vol. 635 (8038), pp. 462-471. Date of Electronic Publication: 2024 Oct 09.

Durvalumab With or Without Tremelimumab in Combination With Chemotherapy in First-Line Metastatic NSCLC: Five-Year Overall Survival Outcomes From the Phase 3 POSEIDON Trial.

Autor: Peters S; Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland. Electronic address: solange.peters@chuv.ch., Cho BC; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea., Luft AV; Leningrad Regional Clinical Hospital, St Petersburg, Russia., Alatorre-Alexander J; Health Pharma Professional Research, Mexico City, Mexico., Geater SL; Prince of Songkla University, Songkhla, Thailand., Laktionov K; Federal State Budgetary Institution 'N.N. Blokhin National Medical Research Center of Oncology' of the Ministry of Health of the Russian Federation (N.N. Blokhin NMRCO), Moscow, Russia., Trukhin D; Odessa National Medical University, Odessa, Ukraine., Kim SW; Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Ursol GM; Acinus, Kropyvnytskyi, Ukraine., Hussein M; Florida Cancer Specialists - Sarah Cannon Research Institute, Leesburg, Florida., Lim FL; Queen Mary University of London, London, United Kingdom., Yang CT; Chang Gung Memorial Hospital, Taoyuan City, Taiwan., Araujo LH; Instituto Nacional de Cancer-INCA, Rio de Janeiro, Brazil., Saito H; Kanagawa Cancer Center, Yokohama, Japan., Reinmuth N; Asklepios Lung Clinic, member of the German Centre for Lung Research (DZL), Munich-Gauting, Germany., Lowery C; AstraZeneca, Gaithersburg, Maryland., Mann H; AstraZeneca, Cambridge, United Kingdom., Stewart R; AstraZeneca, Cambridge, United Kingdom., Jiang H; AstraZeneca, Gaithersburg, Maryland., Garon EB; David Geffen School of Medicine at UCLA, Los Angeles, California., Mok T; Chinese University of Hong Kong, Hong Kong, People's Republic of China., Johnson ML; Sarah Cannon Research Institute, Tennessee Oncology, PLLC, Nashville, Tennessee.

Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2024 Sep 05. Date of Electronic Publication: 2024 Sep 05.