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pro vyhledávání: '"Garland R"'
Autor:
Susanna Nencetti, Doretta Cuffaro, Elisa Nuti, Lidia Ciccone, Armando Rossello, Marina Fabbi, Flavio Ballante, Gabriella Ortore, Grazia Carbotti, Francesco Campelli, Irene Banti, Rosaria Gangemi, Garland R. Marshall, Elisabetta Orlandini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 34-47 (2021)
Uveal melanoma (UM) represents an aggressive type of cancer and currently, there is no effective treatment for this metastatic disease. In the last years, histone deacetylase inhibitors (HDACIs) have been studied as a possible therapeutic treatment f
Externí odkaz:
https://doaj.org/article/dd29395ad7324c7e95f604e5f4b25f96
Autor:
Brice J. Albert, Austin Niu, Rashmi Ramani, Garland R. Marshall, Paul A. Wender, Robert M. Williams, Lee Ratner, Alexander B. Barnes, George B. Kyei
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Current antiretroviral therapy (ART) for HIV/AIDS slows disease progression by reducing viral loads and increasing CD4 counts. Yet ART is not curative due to the persistence of CD4+ T-cell proviral reservoirs that chronically resupply active
Externí odkaz:
https://doaj.org/article/51c1c2571b74471db5299a641c3986a0
Autor:
Eva S. Istvan, Jeremy P. Mallari, Victoria C. Corey, Neekesh V. Dharia, Garland R. Marshall, Elizabeth A. Winzeler, Daniel E. Goldberg
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Pepstatin is a known inhibitor of malarial proteases, but its activity varies between sources. Here, Istvanet al. identify a pepstatin ester as the active component of pepstatin preparations and show that this prodrug is activated by a Plasmodiumeste
Externí odkaz:
https://doaj.org/article/1d38f9612f4048a39eb045aecf7bcf36
Publikováno v:
Polibotánica, Vol 0, Iss 36, Pp 41-61 (2015)
Estudios previos sugieren que las selvas tropicales y paratropicales dominadas por angiospermas tuvieron una distribución importante en América del Norte durante el Cenozoico temprano (Paleoceno-Eoceno). Investigaciones recientes indican que floras
Externí odkaz:
https://doaj.org/article/294c3875f45b4ad591928b2ff48798a1
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123146 (2015)
Theoretical and experimental evidence for non-linear hydrogen bonds in protein helices is ubiquitous. In particular, amide three-centered hydrogen bonds are common features of helices in high-resolution crystal structures of proteins. These high-reso
Externí odkaz:
https://doaj.org/article/fab67cfb47104468b85d76e19086753d
Autor:
Qi Wang, Bruce A Rosa, Bakela Nare, Kerrie Powell, Sergio Valente, Dante Rotili, Antonello Mai, Garland R Marshall, Makedonka Mitreva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 9, p e0004026 (2015)
Due to an increasing problem of drug resistance among almost all parasites species ranging from protists to worms, there is an urgent need to explore new drug targets and their inhibitors to provide new and effective parasitic therapeutics. In this r
Externí odkaz:
https://doaj.org/article/a3ae8a6ca3e445bc8db3fa8fdcbf448b
Autor:
Centeno-González, Naylet Karen, Upchurch, Garland R., Jr., Zúñiga, Gerardo, Porras-Múzquiz, Héctor, Estrada-Ruiz, Emilio
Publikováno v:
In Cretaceous Research May 2024 157
Akademický článek
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The current sparse wavelength range coverage of exoplanet direct imaging observations, and the fact that models are defined using a finite wavelength range, lead both to uncertainties on effective temperature determination.We study these effects usin
Externí odkaz:
http://arxiv.org/abs/1910.00329
Autor:
Garland, R., Irwin, P. G. J.
Sophisticated atmospheric retrieval algorithms, such as Nested Sampling, explore large parameter spaces by iterating over millions of radiative transfer (RT) calculations. Probability distribution functions for retrieved parameters are highly sensiti
Externí odkaz:
http://arxiv.org/abs/1903.03997