Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Garima Dutta"'
Autor:
Sudhakar R. Subramaniam, Iddo Magen, Nicholas Bove, Chunni Zhu, Vincent Lemesre, Garima Dutta, Chris Jean Elias, Henry A. Lester, Marie-Francoise Chesselet
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 170-180 (2018)
In addition to dopaminergic and motor deficits, patients with Parkinson's disease (PD) suffer from non-motor symptoms, including early cognitive and social impairment, that do not respond well to dopaminergic therapy. Cholinergic deficits may contrib
Externí odkaz:
https://doaj.org/article/2c29d81a7fbc4aa49b48c0b5d29bffcf
Autor:
Eliezer Masliah, Amy Paulino, Karin Ledolter, Paula Desplats, Wolfgang Wrasidlo, Igor F. Tsigelny, Dieter Meier, Åge A. Skjevik, Margarita Trejo-Morales, Brian Spencer, Robert Konrat, Chunni Zhu, Garima Dutta, Simona Eleuteri, Marie-Françoise Chesselet, Tania Gonzalez-Ruelas, Cassia R. Overk, Edward Rockenstein, Thomas C. Schwarz, Diana L. Price, Douglas W. Bonhaus, Valentina L. Kouznetsova, Herbert Moessler, Stefan Winter
Publikováno v:
Brain : a journal of neurology, vol 139, iss Pt 12
Abnormal accumulation and propagation of the neuronal protein α-synuclein has been hypothesized to underlie the pathogenesis of Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. Here we report a de novo-developed compound (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e17d784387b62c9ca849ff394fe12f
https://escholarship.org/uc/item/3dk4t6f7
https://escholarship.org/uc/item/3dk4t6f7
Publikováno v:
Journal of Neurochemistry. 122:752-763
Factors released from injured dopaminergic (DA) neurons may trigger microglial activation and set in motion a vicious cycle of neuronal injury and inflammation that fuels progressive DA neurodegeneration in Parkinson's disease. In this study, using p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7b65521981d3fd5b7aeb13889ac6db5
https://doi.org/10.1111/j.1471-4159.2012.07826.x
https://doi.org/10.1111/j.1471-4159.2012.07826.x
Publikováno v:
Fundamental & Clinical Pharmacology. 22:453-464
Research in the last two decades has unveiled an important role for neuroinflammation in the degeneration of the nigrostriatal dopaminergic pathway that constitutes the pathological basis of the prevailing movement disorder, Parkinson's disease (PD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ed803f0f81b34b1b1459d16de26d54
https://doi.org/10.1111/j.1472-8206.2008.00616.x
https://doi.org/10.1111/j.1472-8206.2008.00616.x
Publikováno v:
Journal of Endocrinology. 198:419-427
Previous studies have demonstrated that modest, physiologically relevant increases in maternal cortisol in late gestation result in enlargement of the fetal heart. In this study, we investigated the role of mineralocorticoid receptor (MR) or glucocor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9113d4383ba0dbe4149d2c9c22fde78
https://doi.org/10.1677/joe-08-0022
https://doi.org/10.1677/joe-08-0022
Publikováno v:
Journal of neurochemistry. 122(4)
Factors released from injured dopaminergic (DA) neurons may trigger microglial activation and set in motion a vicious cycle of neuronal injury and inflammation that fuels progressive DA neurodegeneration in Parkinson's disease. In this study, using p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eaf32540bf2714c4f86a7f8abb6b51e9
https://pubmed.ncbi.nlm.nih.gov/22679891
https://pubmed.ncbi.nlm.nih.gov/22679891