Customized nasal prosthesis in continuous positive airway pressure treatment, current trend in treating obstructive sleep apnea for better patient compliance

Autor: Nagam Raja Reddy, Nijamala Sasikala, K V. Guru Charan Karthik, Garikapati Krishna Priya

Publikováno v: Journal of Family Medicine and Primary Care, Vol 8, Iss 8, Pp 2728-2731 (2019)

Snoring is common disorder in India, which is caused due to obstructive sleep apnea. Nasal continuous positive airway pressure (CPAP) is an effective treatment for this condition. Prefabricated nasal masks lack intimate adaptation and cause air leaka

Externí odkaz: https://doaj.org/article/c423473b9e554919b3e2b3538fe113f1

Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug.

Autor: Patel N; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, India., Garikapati KR; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, India.; Academy of Scientific and Innovative Research (AcSIR), Training and Development Complex, CSIR Campus, Taramani, Chennai, India., Makani VKK; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, India., Nair AD; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, India., Vangara N; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, India., Bhadra U; Gene Silencing Group, Centre for Cellular and Molecular Biology, Hyderabad, Telangana State, India., Pal Bhadra M; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, India.

Publikováno v: PloS one [PLoS One] 2018 Feb 02; Vol. 13 (2), pp. e0190245. Date of Electronic Publication: 2018 Feb 02 (Print Publication: 2018).

Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2-c] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis.

Autor: Khan I; Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500007, India; Academy of Scientific and Innovative Research, New Delhi 110 025, India., Garikapati KR; Academy of Scientific and Innovative Research, New Delhi 110 025, India; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India., Shaik AB; Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500007, India., Makani VKK; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India., Rahim A; Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500007, India; Academy of Scientific and Innovative Research, New Delhi 110 025, India., Shareef MA; Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500007, India; Academy of Scientific and Innovative Research, New Delhi 110 025, India., Reddy VG; Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500007, India; Academy of Scientific and Innovative Research, New Delhi 110 025, India., Pal-Bhadra M; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India. Electronic address: manika@iict.res.in., Kamal A; Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500007, India; Academy of Scientific and Innovative Research, New Delhi 110 025, India. Electronic address: ahmedkamal@iict.res.in., Kumar CG; Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500007, India; Academy of Scientific and Innovative Research, New Delhi 110 025, India. Electronic address: cgkumar@iict.res.in.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2018 Jan 20; Vol. 144, pp. 104-115. Date of Electronic Publication: 2017 Dec 05.

miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin.

Autor: Patel N; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, 500007, India., Garikapati KR; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, 500007, India.; Academy of Scientific and Innovative Research (AcSIR), Training and Development Complex, CSIR Campus, CSIR Road, Taramani, Chennai, 600 113, India., Pandita RK; Department of Radiation Oncology, Weill Cornell Medical College, The Methodist Hospital Research Institute, Houston, TX, 77030, USA., Singh DK; Department of Radiation Oncology, Weill Cornell Medical College, The Methodist Hospital Research Institute, Houston, TX, 77030, USA., Pandita TK; Department of Radiation Oncology, Weill Cornell Medical College, The Methodist Hospital Research Institute, Houston, TX, 77030, USA., Bhadra U; Gene Silencing Group, Centre for Cellular and Molecular Biology, Hyderabad, Telangana State, 500007, India., Bhadra MP; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State, 500007, India. manikapb@gmail.com.

Publikováno v: Scientific reports [Sci Rep] 2017 Jun 27; Vol. 7 (1), pp. 4263. Date of Electronic Publication: 2017 Jun 27.

miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1.

Autor: Patel N; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State 500007, India., Garikapati KR; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State 500007, India., Ramaiah MJ; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State 500007, India; School of Chemical and Biotechnology, SASTRA University, Thanjavur, Tamilnadu 613401, India., Polavarapu KK; Department of Genetics, Osmania University, Hyderabad, Telangana State 500007, India., Bhadra U; Gene Silencing Group, Centre for Cellular and Molecular Biology, Hyderabad, Telangana State 500007, India., Bhadra MP; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, Telangana State 500007, India. Electronic address: manikapb@gmail.com.

Publikováno v: Life sciences [Life Sci] 2016 Nov 01; Vol. 164, pp. 60-70. Date of Electronic Publication: 2016 Sep 03.