Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Garik V. Mkrtchyan"'
Autor:
Garik V. Mkrtchyan, Alexander Veviorskiy, Evgeny Izumchenko, Anastasia Shneyderman, Frank W. Pun, Ivan V. Ozerov, Alex Aliper, Alex Zhavoronkov, Morten Scheibye-Knudsen
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-9 (2022)
Abstract Multiple cancer types have limited targeted therapeutic options, in part due to incomplete understanding of the molecular processes underlying tumorigenesis and significant intra- and inter-tumor heterogeneity. Identification of novel molecu
Externí odkaz:
https://doaj.org/article/8d0e50351b0348ee9424beea95768a36
Autor:
Adelheid Weidinger, Nadja Milivojev, Arthur Hosmann, J. Catharina Duvigneau, Csaba Szabo, Gabor Törö, Laurin Rauter, Annette Vaglio-Garro, Garik V. Mkrtchyan, Lidia Trofimova, Rinat R. Sharipov, Alexander M. Surin, Irina A. Krasilnikova, Vsevolod G. Pinelis, Laszlo Tretter, Rudolf Moldzio, Hülya Bayır, Valerian E. Kagan, Victoria I. Bunik, Andrey V. Kozlov
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102669- (2023)
Brain injury is accompanied by neuroinflammation, accumulation of extracellular glutamate and mitochondrial dysfunction, all of which cause neuronal death. The aim of this study was to investigate the impact of these mechanisms on neuronal death.Pati
Externí odkaz:
https://doaj.org/article/427e252d29b84f7382a2fca0e3a2b261
The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals
Autor:
Anastasia V. Shindyapina, Tatiana V. Komarova, Ekaterina V. Sheshukova, Natalia M. Ershova, Vadim N. Tashlitsky, Alexander V. Kurkin, Ildar R. Yusupov, Garik V. Mkrtchyan, Murat Y. Shagidulin, Yuri L. Dorokhov
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
The healthy human body contains small amounts of metabolic formaldehyde (FA) that mainly results from methanol oxidation by pectin methylesterase, which is active in a vegetable diet and in the gastrointestinal microbiome. With age, the ability to ma
Externí odkaz:
https://doaj.org/article/273250f2cb5a40c69942aca8b084f5ec
Autor:
Indra Heckenbach, Garik V. Mkrtchyan, Michael Ben Ezra, Daniela Bakula, Jakob Sture Madsen, Malte Hasle Nielsen, Denise Oró, Brenna Osborne, Anthony J Covarrubias, M. Laura Idda, Myriam Gorospe, Laust Mortensen, Eric Verdin, Rudi Westendorp, Morten Scheibye-Knudsen
Publikováno v:
Heckenbach, I, Mkrtchyan, G V, Ezra, M B, Bakula, D, Madsen, J S, Nielsen, M H, Oró, D, Osborne, B, Covarrubias, A J, Idda, M L, Gorospe, M, Mortensen, L, Verdin, E, Westendorp, R & Scheibye-Knudsen, M 2022, ' Nuclear morphology is a deep learning biomarker of cellular senescence ', Nature Aging, vol. 2, no. 8, pp. 742-755 . https://doi.org/10.1038/s43587-022-00263-3
Cellular senescence is an important factor in aging and many age-related diseases, but understanding its role in health is challenging due to the lack of exclusive or universal markers. Using neural networks, we predict senescence from the nuclear mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5eda787a7c1be611f28987041f5a0c
https://curis.ku.dk/ws/files/319160606/s43587_022_00263_3.pdf
https://curis.ku.dk/ws/files/319160606/s43587_022_00263_3.pdf
Autor:
Indra Heckenbach, Michael Ben Ezra, Garik V. Mkrtchyan, Jakob Sture Madsen, Malte Hasle Nielsen, Denise Oro, Laust H. Mortensen, Eric Verdin, Rudi G.J. Westendorp, Morten Scheibye-Knudsen
Publikováno v:
SSRN Electronic Journal.