Through-Space, Lone-Pair Promoted Aromatic Substitution: A Relay Mechanism Can Beat Out Direct Activation.

Autor: Kazim M; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.; Current address: Chemical Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA., Feng Z; Department of Chemistry, University of California, 1 Shields Ave, Davis, CA 95616, USA., Vemulapalli S; Department of Chemistry, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON L2S 3A1, Canada., Siegler MA; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA., Chopra A; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA., Minh Nguyen P; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA., Gargiulo Holl M; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA., Guan L; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA., Dudding T; Department of Chemistry, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON L2S 3A1, Canada., Tantillo DJ; Department of Chemistry, University of California, 1 Shields Ave, Davis, CA 95616, USA., Lectka T; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Sep 15; Vol. 29 (52), pp. e202301550. Date of Electronic Publication: 2023 Aug 13.