Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Gareth W, Roberts"'
Autor:
David Dallimore, Gareth W. Roberts, Leah McLaughlin, Gail Williams Wales Renal, James Chess, Jane Noyes
Background Despite home dialysis having many advantages, take-up by people with established renal failure is low in many countries. Previous studies highlight complex social, psychological, economic and health-system obstacles to patients choosing ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8573ba762d892dca79d7e1652ec3083
https://doi.org/10.21203/rs.3.rs-294000/v1
https://doi.org/10.21203/rs.3.rs-294000/v1
Autor:
Martin S Davey, Chan-Yu Lin, Gareth W Roberts, Sinéad Heuston, Amanda C Brown, James A Chess, Mark A Toleman, Cormac G M Gahan, Colin Hill, Tanya Parish, John D Williams, Simon J Davies, David W Johnson, Nicholas Topley, Bernhard Moser, Matthias Eberl
Publikováno v:
PLoS Pathogens, Vol 7, Iss 5, p e1002040 (2011)
Human blood Vγ9/Vδ2 T cells, monocytes and neutrophils share a responsiveness toward inflammatory chemokines and are rapidly recruited to sites of infection. Studying their interaction in vitro and relating these findings to in vivo observations in
Externí odkaz:
https://doaj.org/article/b9958d4c50344f4c8fc4043f37808ff3
Autor:
Matthias Eberl, Gareth W Roberts, Simone Meuter, John D Williams, Nicholas Topley, Bernhard Moser
Publikováno v:
PLoS Pathogens, Vol 5, Iss 2, p e1000308 (2009)
Vgamma9/Vdelta2 T cells are a minor subset of T cells in human blood and differ from other T cells by their immediate responsiveness to microbes. We previously demonstrated that the primary target for Vgamma9/Vdelta2 T cells is (E)-4-hydroxy-3-methyl
Externí odkaz:
https://doaj.org/article/520603519852445c9cba68695840ab82
Publikováno v:
Optical Measurement Systems for Industrial Inspection XI.
We describe a full field heterodyne interferometry system where the object beam is shifted by a high frequency with respect to the reference beam. The optical path difference between the object and reference beam is encoded in the phase of the envelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e733bbff4d865a6cbd61de9aa69007
https://doi.org/10.1117/12.2525827
https://doi.org/10.1117/12.2525827
Autor:
Anna Rita, Liuzzi, Ann, Kift-Morgan, Melisa, Lopez-Anton, Ida M, Friberg, Jingjing, Zhang, Amy C, Brook, Gareth W, Roberts, Kieron L, Donovan, Chantal S, Colmont, Mark A, Toleman, Timothy, Bowen, David W, Johnson, Nicholas, Topley, Bernhard, Moser, Donald J, Fraser, Matthias, Eberl
Publikováno v:
The Journal of Immunology Author Choice
The antimicrobial responsiveness and function of unconventional human T cells are poorly understood, with only limited access to relevant specimens from sites of infection. Peritonitis is a common and serious complication in individuals with end-stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0898f144ff48a7000d6d27a9bd708e3
https://pubmed.ncbi.nlm.nih.gov/27527598
https://pubmed.ncbi.nlm.nih.gov/27527598
We present a description of our method to process a set of autocollimator-based deflectometer 1-dimensional line-scans taken over a large optical surface and reconstruct them to a best-fit conic-section surface. The challenge with our task is that ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd40a230c682a5ffbf35774538ad738
Publikováno v:
Proc. SPIE 9628, Optical Systems Design 2015: Optical Fabrication, Testing, and Metrology V
The use of autocollimator-based profilometers of the Nanometer Optical measuring Machine (NOM) design has been reported for the evaluation of X-ray optics for some time. We report a related development in the use of a non-contact NOM profilometer for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9b0949947264cc093ca451ef84eb09
https://doi.org/10.1117/12.2191322
https://doi.org/10.1117/12.2191322
Autor:
Gareth W. Roberts, Tobias Hartmann, Nobuo Ida, Konrad Beyreuther, David Allsop, Sophie Bieger, Colin L. Masters, Pentti J. Tienari, Carlos G. Dotti, Babara Brühl, Klaus Unsicker
Publikováno v:
Nature Medicine. 3:1016-1020
The Alzheimer amyloid precursor protein (APP) is cleaved by several proteases, the most studied, but still unidentified ones, are those involved in the release of a fragment of APP, the amyloidogenic beta-protein A beta. Proteolysis by gamma-secretas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec32b3a2012a4ae38cd8d23ad9452397
https://doi.org/10.1038/nm0997-1016
https://doi.org/10.1038/nm0997-1016
Publikováno v:
Neurodegeneration. 5:251-258
Neurofibrillary pathology is seen in a wide variety of disorders such as Alzheimer's disease (AD), progressive supranuclear palsy and the Parkinsonism-dementia amyotrophic lateral sclerosis complex of Guam. To assess the pathological importance of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a7690c9bb8bcd82d91a79129d1f462
https://doi.org/10.1006/neur.1996.0033
https://doi.org/10.1006/neur.1996.0033
Autor:
Jordi Perez-Tur, Susanne Froelich, Guy Prihar, Richard Crook, Matt Baker, Karen Duff, Michelle Wragg, Frances Busfield, Corinne Lendon, Robert F. Clark, Penelope Roques, Rebecca A. Fuldner, Janet Johnston, Richard Cowburn, Charlotte Forsell, Karin Axelman, Lena Lilius, Henry Houlden, Eric Karran, Gareth W. Roberts, Martin Rossor, Mark D. Adams, John Hardy, Alison Goate, Lars Lannfelt, Michael Hutton
Publikováno v:
Scopus-Elsevier
A series of mutations has been reported in the presenilin-1 (PS-1) gene which cause early onset Alzheimer's disease (AD). The mutations reported to date have encoded missense mutations which alter residues conserved between PS-1 and the presenilin-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33eba3441bc9c60a7a66145acc75b9ba
https://doi.org/10.1097/00001756-199512000-00071
https://doi.org/10.1097/00001756-199512000-00071