Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gareth R.I. Barker"'
Autor:
Matthew T. Birnie, Matthew D.B. Claydon, Benjamin P. Flynn, Mitsuhiro Yoshimura, Yvonne M. Kershaw, Rebecca C.R. Demski-Allen, Gareth R.I. Barker, E. Clea Warburton, Zuner A. Bortolotto, Stafford L. Lightman, Becky L. Conway-Campbell
Neuropsychiatric disorders such as major depression and schizophrenia are highly prevalent and contribute substantially to disease burden worldwide. Despite this, progress understanding the pathophysiology has remained largely elusive, yet these diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d6aba9fffa08156304733ee8ebb3d98
https://doi.org/10.1101/2022.07.12.499774
https://doi.org/10.1101/2022.07.12.499774
Publikováno v:
Barker, G R, Wong, L F, Uney, J B & Warburton, E C 2020, ' CREB transcription in the medial prefrontal cortex regulates the formation of long-term associative recognition memory ', Learning and Memory, vol. 27, no. 2, pp. 45-51 . https://doi.org/10.1101/lm.050021.119
Learn Mem
Learn Mem
The medial prefrontal cortex (mPFC) is known to be critical for specific forms of long-term recognition memory, however the cellular mechanisms in the mPFC that underpin memory maintenance have not been well characterized. This study examined the imp
Autor:
Kyriacos A. Mitrophanous, Gareth R.I. Barker, G. Scott Ralph, Liang-Fong Wong, Paul J Banks, Hannah Scott, Zafar I. Bashir, James B. Uney, E. Clea Warburton
Publikováno v:
Barker, G, Banks, P, Scott, H, Wong, L-F, Bashir, Z, Uney, J, Warburton, C, Banks, P J & Scott Ralph, G 2017, ' Separate elements of episodic memory subserved by distinct hippocampal-prefrontal connections ', Nature Neuroscience, vol. 20, no. 2, pp. 242–250 . https://doi.org/10.1038/nn.4472
Episodic memory formation depends on information about a stimulus being integrated within a precise spatial and temporal context, a process dependent on the hippocampus and prefrontal cortex. Investigations of putative functional interactions between
Publikováno v:
Neurochemical Research
Scullion, S E, Barker, G R I, Warburton, E C, Randall, A D & Brown, J T 2019, ' Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy ', Neurochemical Research, vol. 44, no. 3, pp. 617-626 . https://doi.org/10.1007/s11064-018-2487-x
Scullion, S E, Barker, G R I, Warburton, E C, Randall, A D & Brown, J T 2019, ' Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy ', Neurochemical Research, vol. 44, no. 3, pp. 617-626 . https://doi.org/10.1007/s11064-018-2487-x
Neurodegenerative diseases affecting cognitive dysfunction, such as Alzheimer’s disease and fronto-temporal dementia, are often associated impairments in the visual recognition memory system. Recent evidence suggests that synaptic plasticity, in pa
Publikováno v:
Scott, H, Smith, A E, Barker, G R, Uney, J B & Warburton, E C 2017, ' Contrasting roles for DNA methyltransferases and histone deacetylases in single-item and associative recognition memory ', Neuroepigenetics, vol. 9 . https://doi.org/10.1016/j.nepig.2017.02.001
Scott, H, Smith, A E, Barker, G R, Uney, J B & Warburton, E C 2017, ' Contrasting roles for DNA methyltransferases and histone deacetylases in single-item and associative recognition memory ', Neuroepigenetics, vol. 9, pp. 1-9 . https://doi.org/10.1016/j.nepig.2017.02.001
Neuroepigenetics
Scott, H, Smith, A E, Barker, G R, Uney, J B & Warburton, E C 2017, ' Contrasting roles for DNA methyltransferases and histone deacetylases in single-item and associative recognition memory ', Neuroepigenetics, vol. 9, pp. 1-9 . https://doi.org/10.1016/j.nepig.2017.02.001
Neuroepigenetics
This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) [grant number BB/I00310X/1]. HS and AES were supported by Medical Research Council (MRC) Doctoral Training Grants Recognition memory enables us to judge whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ec1bbe0deeff2818130563bb506cb0
https://research-information.bris.ac.uk/en/publications/c90b8677-4a94-416e-b290-a24dcd57a9d1
https://research-information.bris.ac.uk/en/publications/c90b8677-4a94-416e-b290-a24dcd57a9d1
Publikováno v:
Hippocampus. 24:934-942
Atypical isoforms of protein kinase C (aPKCs; particularly protein kinase M zeta: PKMζ) have been hypothesized to be necessary and sufficient for the maintenance of long-term potentiation (LTP) and long term memory by maintaining postsynaptic AMPA r
Publikováno v:
Barker, G R I, Evuarherhe, O & Warburton, E C 2019, ' Remembering the order of serially presented objects : A matter of time? ', Brain and Neuroscience Advances, vol. 3 . https://doi.org/10.1177/2398212819883088
Brain and Neuroscience Advances
Brain and Neuroscience Advances
Remembering the sequence, in which stimuli are encountered or events have occurred, is a key process in episodic memory and can also facilitate recognition memory. Rodents, when presented with a sequence of objects, will explore the object encountere
Autor:
E. C. Warburton, Gareth R.I. Barker
Publikováno v:
Cerebral Cortex (New York, NY)
Object-in-place associative recognition memory depends on an interaction between the hippocampus (HPC), perirhinal (PRH), and medial prefrontal (mPFC) cortices, yet the contribution of glutamate receptor neurotransmission to these interactions is unk
Autor:
Costanza Burattini, Zafar I. Bashir, Gareth R.I. Barker, E. Clea Warburton, Francesco Tamagnini, Giorgio Aicardi
Publikováno v:
The Journal of Physiology
Synaptic plasticity in perirhinal cortex is essential for recognition memory. Nitric oxide and endocannabinoids (eCBs), which are produced in the postsynaptic cell and act on the presynaptic terminal, are implicated in mechanisms of long-term potenti
Autor:
Gareth R.I. Barker, E. C. Warburton, Emma S J Robinson, Sriharsha Kantamneni, Laura Ceolin, James A. Monn, Graham L. Collingridge, Lydia Hanna, Stephen M. Fitzjohn, Zuner A. Bortolotto, Laura Murray, David Lodge
Publikováno v:
The Journal of Neuroscience. 31:6721-6731
Group II metabotropic receptors (mGluRs) regulate central synaptic transmission by modulating neurotransmitter release. However, the lack of pharmacological tools differentiating between mGlu2 and mGlu3 receptors has hampered identification of the ro